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> Protein (NX_Q8TDQ7)
Protein (NX_Q8TDQ7)
Protein
Gene SymbolGNPDA2 to neXtProt (NX_Q8TDQ7)
DescriptionGlucosamine-6-phosphate isomerase 2
Chromosome4
Location4p12 (44684217 ~ 44728612) to Ensembl
Sequene Features : Isoforms 5, Variants 32, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N-acetylglucosamine metabolic process
.carbohydrate metabolic process
.hydrolase activity
.glucosamine-6-phosphate deaminase activity
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 32 2
2014-09-19protein level
5 25 2
2014-05-27protein level
5 25 3
2014-02-25protein level
5 25 3
2013-12-09protein level
5 21 3
2013-11-01protein level
5 20 1
2013-09-12protein level
5 20 1
2013-08-17protein level
5 20 1
2013-07-15protein level
3 8 0
2013-06-11protein level
3 8 0
2013-02-12protein level
3 3 0
2012-12-20protein level
3 3 0
2012-10-30protein level
3 5 0
2012-10-07protein level
3 5 0
2012-08-24protein level
3 4 0
2012-07-28protein level
3 4 0
2012-06-08protein level
3 5 0
2012-05-07protein level
3 5 0
2012-04-10protein level
3 5 0
2012-01-13protein level
3 3 0
2011-12-20protein level
3 3 0
2011-11-11protein level
3 3 0
2011-08-23protein level
3 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TDQ7-1
0 10 5 31064.5226
NX_Q8TDQ7-2
1 10 4 30935.4803
NX_Q8TDQ7-3
0 8 5 29154.5374
NX_Q8TDQ7-4
1 8 3 22897.3196
NX_Q8TDQ7-5
1 10 3 27073.5534
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10275006,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
2 EBI-10275006,EBI-2798672 AMDHD2  
  .N-acetylneuraminate catabolic process
.N-acetylglucosamine metabolic process
.carbohydrate metabolic process
.metal ion binding
.N-acetylglucosamine-6-phosphate deacetylase activity
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
ascites25
bladder66
blood8
bone41
bone marrow20
brain40
cervix20
connective tissue26
embryonic tissue4
eye23
heart22
intestine4
kidney28
liver19
lung5
lymph node33
mammary gland6
muscle37
nerve64
ovary19
pancreas32
placenta3
prostate15
skin28
stomach20
testis20
uterus21
vascular58
Health State
TissuesTPM*
normal20
adrenal tumor79
chondrosarcoma48
gastrointestinal tumor8
germ cell tumor7
glioma9
kidney tumor43
leukemia10
liver tumor20
lymphoma13
non-neoplasia20
ovarian tumor13
pancreatic tumor28
prostate cancer19
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult7
embryoid body14
blastocyst16
fetus10
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue11.5
adrenal gland14.7
appendix10.1
bone marrow5.3
cerebral cortex15.4
colon9
duodenum7.4
esophagus10.6
gallbladder12.5
heart muscle13.7
kidney12.8
liver2.3
lung10.4
lymph node12.6
ovary23.1
pancreas4
placenta5.6
prostate15.2
salivary gland7.4
skin8.5
small intestine8.4
spleen11.4
stomach7.9
testis12.3
thyroid gland18.6
urinary bladder15.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613222, gene) Glucosamine-6-phosphate deaminase 2; GNPDA2OMIM


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