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> Protein (NX_Q8TEB7)
Protein (NX_Q8TEB7)
Protein
Gene SymbolRNF128 to neXtProt (NX_Q8TEB7)
DescriptionE3 ubiquitin-protein ligase RNF128
ChromosomeX
LocationXq22.3 (105937024 ~ 106040223) to Ensembl
Sequene Features : Isoforms 2, Variants 69, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of cytokine biosynthetic process .ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.perinuclear region of cytoplasm
.integral component of membrane
.cytoskeleton
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 69 3
2014-09-19protein level
2 45 3
2014-05-27protein level
2 45 3
2014-02-25protein level
2 45 3
2013-12-09protein level
2 36 3
2013-11-01protein level
2 35 3
2013-09-12protein level
2 35 3
2013-08-17protein level
2 35 3
2013-07-15protein level
2 21 3
2013-06-11protein level
2 21 3
2013-02-12protein level
2 10 3
2012-12-20protein level
2 8 3
2012-10-30protein level
2 12 3
2012-10-07protein level
2 12 3
2012-08-24protein level
2 11 3
2012-07-28protein level
2 11 3
2012-06-08protein level
2 17 3
2012-05-07protein level
2 17 3
2012-04-10protein level
2 17 3
2012-01-13protein level
2 10 3
2011-12-20protein level
2 10 3
2011-11-11protein level
2 10 3
2011-08-23protein level
2 10 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TEB7-1
8 7 0 46491.2761
NX_Q8TEB7-2
6 7 0 44589.1151
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2341619,EBI-742887 CEP76  
  .regulation of centriole replication
.organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .protein complex
.cytosol
.centriole
.centrosome
2 EBI-2341619,EBI-743771 APPBP2  
  .intracellular transport
.metabolic process
.intracellular protein transport
.microtubule motor activity .cytoplasmic vesicle membrane
.microtubule associated complex
.microtubule
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland121
bladder33
bone marrow20
brain55
ear62
embryonic tissue4
intestine25
kidney66
liver53
lung2
mammary gland13
muscle9
pancreas60
pituitary gland121
placenta35
salivary gland98
skin4
stomach20
thyroid21
uterus8
vascular38
Health State
TissuesTPM*
normal17
adrenal tumor237
bladder carcinoma113
colorectal tumor53
gastrointestinal tumor16
germ cell tumor3
glioma18
head and neck tumor7
kidney tumor116
liver tumor62
non-neoplasia10
pancreatic tumor47
skin tumor7
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult14
blastocyst16
fetus12
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland36
appendix2
cerebral cortex3.3
colon23.5
duodenum58.5
esophagus5
gallbladder37.6
kidney27.2
liver60.9
lung16.4
ovary2
pancreas7.7
placenta11
prostate2.5
salivary gland21
skin6.1
small intestine57.2
stomach38.7
thyroid gland27.7
urinary bladder32.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300439, gene) Ring finger protein 128; RNF128OMIM


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