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> Protein (NX_Q8TEP8)
Protein (NX_Q8TEP8)
Protein
Gene SymbolCEP192 to neXtProt (NX_Q8TEP8)
DescriptionCentrosomal protein of 192 kDa
Chromosome18
Location18p11.21 (12991361 ~ 13125051) to Ensembl
Sequene Features : Isoforms 3, Variants 276, PTMs 12 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.centrosome duplication
.spindle assembly
.negative regulation of phosphatase activity
  + 3 more...
.phosphatase binding .cytosol
.centriole
.centrosome
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 276 12
2014-09-19protein level
3 225 12
2014-05-27protein level
2 193 12
2014-02-25protein level
2 192 12
2013-12-09protein level
2 177 12
2013-11-01protein level
2 174 12
2013-09-12protein level
2 174 11
2013-08-17protein level
2 174 11
2013-07-15protein level
2 125 9
2013-06-11protein level
2 125 9
2013-02-12protein level
2 79 9
2012-12-20protein level
2 90 9
2012-10-30protein level
2 91 9
2012-10-07protein level
2 91 6
2012-08-24protein level
2 89 6
2012-07-28protein level
2 89 6
2012-06-08protein level
2 13 6
2012-05-07protein level
2 13 6
2012-04-10protein level
2 13 6
2012-01-13protein level
2 13 6
2011-12-20protein level
2 13 6
2011-11-11protein level
2 13 3
2011-08-23protein level
2 13 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TEP8-1
0 86 0 213012.6319
NX_Q8TEP8-2
0 56 0 153485.9338
NX_Q8TEP8-3
27 85 0 278936.9768
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2339778,EBI-357253 PPP1CA  
  .positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
.cell division
.branching morphogenesis of an epithelial tube
  + 15 more...
.metal ion binding
.ribonucleoprotein complex binding
.phosphatase activity
.protein serine/threonine phosphatase activity
.PTW/PP1 phosphatase complex
.MLL5-L complex
.extracellular exosome
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites50
blood32
bone marrow20
brain18
cervix20
connective tissue26
ear62
embryonic tissue28
eye9
heart22
intestine12
kidney42
liver9
lung20
lymph node89
mammary gland13
mouth15
muscle28
ovary29
pancreas18
parathyroid48
pituitary gland60
placenta17
prostate31
skin4
stomach62
testis22
thymus75
thyroid85
trachea57
uterus21
Health State
TissuesTPM*
normal30
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma12
colorectal tumor8
gastrointestinal tumor50
germ cell tumor18
head and neck tumor37
kidney tumor29
leukemia42
lung tumor9
non-neoplasia20
ovarian tumor26
pancreatic tumor19
primitive neuroectodermal tumor of the CNS15
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor44
Developmental Stage
TissuesTPM*
adult29
embryoid body14
blastocyst32
fetus44
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.4
adrenal gland5.3
appendix9.1
bone marrow15.8
cerebral cortex6
colon8.9
duodenum7.3
esophagus6.6
gallbladder12.8
heart muscle5.7
kidney5.9
liver2.6
lung8.8
lymph node15.3
ovary14.3
pancreas3.8
placenta6.5
prostate9.7
salivary gland6.7
skin9.1
small intestine8.8
spleen8.9
stomach8
testis14.4
thyroid gland9.8
urinary bladder11.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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