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> Protein (NX_Q8TER5)
Protein (NX_Q8TER5)
Protein
Gene SymbolARHGEF40 to neXtProt (NX_Q8TER5)
DescriptionRho guanine nucleotide exchange factor 40
Chromosome14
Location14q11.2 (21538429 ~ 21558399) to Ensembl
Sequene Features : Isoforms 4, Variants 155, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .Rho guanyl-nucleotide exchange factor activity .cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 155 9
2014-09-19protein level
4 118 9
2014-05-27protein level
4 118 9
2014-02-25protein level
4 118 9
2013-12-09protein level
4 92 9
2013-11-01protein level
4 87 7
2013-09-12protein level
4 87 7
2013-08-17protein level
4 87 7
2013-07-15protein level
4 60 7
2013-06-11protein level
4 60 7
2013-02-12protein level
4 41 18
2012-12-20protein level
4 40 18
2012-10-30protein level
4 52 18
2012-10-07protein level
4 52 5
2012-08-24protein level
4 52 5
2012-07-28protein level
4 52 5
2012-06-08protein level
4 5 5
2012-05-07protein level
4 5 5
2012-04-10protein level
4 5 5
2012-01-13protein level
4 5 5
2011-12-20protein level
4 7 5
2011-11-11protein level
4 7 5
2011-08-23protein level
4 7 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TER5-1
0 69 0 164554.8713
NX_Q8TER5-2
0 42 0 88702.6804
NX_Q8TER5-3
4 64 0 162698.2071
NX_Q8TER5-4
1 66 0 159598.3663
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10275150,EBI-741724 SPERT  
  .N/A .N/A .cytoplasmic membrane-bounded vesicle
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bone83
brain28
connective tissue40
embryonic tissue84
eye47
heart44
intestine60
kidney47
liver43
lung20
mammary gland13
muscle18
nerve64
ovary88
pancreas70
placenta84
prostate10
skin37
spleen37
testis18
thyroid85
trachea19
uterus38
Health State
TissuesTPM*
normal38
adrenal tumor79
chondrosarcoma84
colorectal tumor88
germ cell tumor30
glioma111
head and neck tumor22
kidney tumor72
liver tumor31
lung tumor29
ovarian tumor39
pancreatic tumor57
primitive neuroectodermal tumor of the CNS39
prostate cancer19
retinoblastoma21
skin tumor63
soft tissue/muscle tissue tumor23
uterine tumor66
Developmental Stage
TissuesTPM*
adult43
embryoid body42
blastocyst162
fetus46
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue31.7
adrenal gland49.3
appendix15.9
bone marrow5.4
cerebral cortex15.4
colon15.2
duodenum7.7
esophagus5.1
gallbladder27.3
heart muscle10.4
kidney10.9
liver14.1
lung18
lymph node4.5
ovary30.5
pancreas14.1
placenta11.8
prostate12.3
salivary gland28.9
skin8.7
small intestine9.2
spleen52.6
stomach10.3
testis8.9
thyroid gland17.6
urinary bladder11.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610018, gene) Solo geneOMIM


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