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> Protein (NX_Q8TF40)
Protein (NX_Q8TF40)
Protein
Gene SymbolFNIP1 to neXtProt (NX_Q8TF40)
DescriptionFolliculin-interacting protein 1
Chromosome5
Location5q31.1 (130977407 ~ 131132710) to Ensembl
Sequene Features : Isoforms 3, Variants 132, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of pro-B cell differentiation
.positive regulation of GTPase activity
.negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
  + 9 more...
.guanyl-nucleotide exchange factor activity .cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 132 7
2014-09-19protein level
3 113 7
2014-05-27protein level
3 112 7
2014-02-25protein level
3 106 7
2013-12-09protein level
3 96 7
2013-11-01protein level
3 92 7
2013-09-12protein level
3 92 7
2013-08-17protein level
3 92 7
2013-07-15protein level
3 49 6
2013-06-11protein level
3 49 6
2013-02-12protein level
3 32 8
2012-12-20protein level
3 31 8
2012-10-30protein level
3 33 8
2012-10-07protein level
3 33 4
2012-08-24protein level
3 22 4
2012-07-28protein level
3 22 4
2012-06-08protein level
3 22 4
2012-05-07protein level
3 22 4
2012-04-10protein level
3 22 4
2012-01-13protein level
3 16 4
2011-12-20protein level
3 16 4
2011-11-11protein level
3 16 4
2011-08-23protein level
3 16 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8TF40-1
0 57 1 130471.5712
NX_Q8TF40-2
1 27 0 56765.0776
NX_Q8TF40-3
1 54 1 127361.977
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2946919,EBI-712001 GABARAP  
  .membrane fusion
.nucleophagy
.extrinsic apoptotic signaling pathway via death domain receptors
  + 5 more...
.GABA receptor binding
.beta-tubulin binding
.microtubule binding
.perinuclear region of cytoplasm
.cell body
.cytoplasmic vesicle
  + 13 more...
2 EBI-2946919,EBI-746969 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
bladder33
blood16
bone41
bone marrow61
brain14
connective tissue6
embryonic tissue18
eye4
heart11
intestine17
kidney18
liver68
lung17
lymph22
lymph node77
mouth15
ovary9
pancreas37
parathyroid48
placenta10
prostate21
skin33
stomach31
testis25
thymus12
thyroid21
trachea19
uterus4
vascular58
Health State
TissuesTPM*
normal26
chondrosarcoma48
colorectal tumor26
gastrointestinal tumor33
germ cell tumor15
head and neck tumor14
leukemia31
lung tumor9
lymphoma13
non-neoplasia51
prostate cancer19
skin tumor23
Developmental Stage
TissuesTPM*
adult19
blastocyst65
neonate32
fetus48
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.1
adrenal gland9.4
appendix7.4
bone marrow9.2
cerebral cortex9.7
colon8.2
duodenum8.4
esophagus7.2
gallbladder9.6
heart muscle8.2
kidney8.1
liver7.6
lung6.7
lymph node6.4
ovary13.4
pancreas3.5
placenta8.4
prostate9.4
salivary gland3.6
skin5.8
small intestine7
spleen6.8
stomach8.9
testis16.7
thyroid gland12.6
urinary bladder8.3
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*610594, gene) Folliculin-interacting protein 1; FNIP1OMIM


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