|
| Protein |
|
| Gene Symbol | ZNF473 to neXtProt (NX_Q8WTR7) |
| Description | Zinc finger protein 473 |
| Chromosome | 19 |
| Location | 19q13.33 (50528971 ~ 50556671) to Ensembl |
|
|
Sequene Features : Isoforms 1, Variants 118, PTMs 0 to neXtProt Sequence Features
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|
Gene
Ontologies |
| GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
.mRNA 3'-end processing
.gene expression
.histone mRNA metabolic process
+ 4 more... |
.metal ion binding
.DNA binding |
.Cajal body
.nucleoplasm |
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| |
|
| Proteomic Evidences |
|
| |
|
| Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
|
| 2015-01-01 | | protein level | | | | | | | 1 |
| 118 |
| 0 |
|
| 2014-09-19 | | protein level | | | | | | | 1 |
| 95 |
| 0 |
|
| 2014-05-27 | | protein level | | | | | | | 1 |
| 95 |
| 0 |
|
| 2014-02-25 | | protein level | | | | | | | 1 |
| 94 |
| 0 |
|
| 2013-12-09 | | protein level | | | | | | | 1 |
| 76 |
| 0 |
|
| 2013-11-01 | | protein level | | | | | | | 1 |
| 74 |
| 0 |
|
| 2013-09-12 | | protein level | | | | | | | 1 |
| 74 |
| 0 |
|
| 2013-08-17 | | protein level | | | | | | | 1 |
| 74 |
| 0 |
|
| 2013-07-15 | | protein level | | | | | | | 1 |
| 50 |
| 0 |
|
| 2013-06-11 | | protein level | | | | | | | 1 |
| 50 |
| 0 |
|
| 2013-02-12 | | protein level | | | | | | | 1 |
| 35 |
| 0 |
|
| 2012-12-20 | | protein level | | | | | | | 1 |
| 35 |
| 0 |
|
| 2012-10-30 | | protein level | | | | | | | 1 |
| 41 |
| 0 |
|
| 2012-10-07 | | protein level | | | | | | | 1 |
| 41 |
| 0 |
|
| 2012-08-24 | | protein level | | | | | | | 1 |
| 38 |
| 0 |
|
| 2012-07-28 | | protein level | | | | | | | 1 |
| 38 |
| 0 |
|
| 2012-06-08 | | protein level | | | | | | | 1 |
| 42 |
| 0 |
|
| 2012-05-07 | | protein level | | | | | | | 1 |
| 32 |
| 0 |
|
| 2012-04-10 | | protein level | | | | | | | 1 |
| 32 |
| 0 |
|
| 2012-01-13 | | protein level | | | | | | | 1 |
| 15 |
| 0 |
|
| 2011-12-20 | | protein level | | | | | | | 1 |
| 15 |
| 0 |
|
| 2011-11-11 | | protein level | | | | | | | 1 |
| 15 |
| 0 |
|
| 2011-08-23 | | protein level | | | | | | | 1 |
| 15 |
| 0 |
|
|
| |
|
| Protein Isoforms |
|
| |
| |
|
| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
|
|
| |
|
| Interacting Partners |
|
| |
|
| No. |
Exp. ref. |
Symbol |
|
PE |
Pr |
Ab |
Di |
|
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
| 1 |
EBI-751409,EBI-1210440 |
ZSCAN12 |
|
| | | | |
.transcription, DNA-templated |
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding |
.nucleus |
|
| 2 |
EBI-751409,EBI-10177272 |
ZNF250 |
|
| | | | |
.regulation of transcription, DNA-templated
.transcription, DNA-templated |
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding |
.nucleus |
|
| 3 |
EBI-751409,EBI-750020 |
CLK2 |
|
| | | | |
.protein autophosphorylation
.negative regulation of gluconeogenesis
.regulation of RNA splicing
+ 3 more... |
.ATP binding
.protein tyrosine kinase activity
.protein serine/threonine/tyrosine kinase activity
.protein serine/threonine kinase activity |
.nuclear speck
.nucleoplasm
.nucleus |
|
| 4 |
EBI-751409,EBI-10171774 |
KRTAP10-8 |
|
| | | | |
.N/A |
.N/A |
.keratin filament |
|
| 5 |
EBI-751409,EBI-10172052 |
KRTAP10-9 |
|
| | | | |
.N/A |
.N/A |
.keratin filament |
|
| 6 |
EBI-751409,EBI-10240849 |
ZNF792 |
|
| | | | |
.regulation of transcription, DNA-templated
.transcription, DNA-templated |
.metal ion binding
.DNA binding |
.nucleus |
|
| 7 |
EBI-751409,EBI-1051531 |
DHX57 |
|
| | | | |
.RNA processing |
.metal ion binding
.poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity |
.mitochondrion
.nucleus |
|
| 8 |
EBI-751409,EBI-8637627 |
AEN |
|
| | | | |
.nucleic acid phosphodiester bond hydrolysis
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.response to ionizing radiation |
.exonuclease activity
.nucleic acid binding |
.nuclear membrane
.nucleolus
.nucleoplasm
.nucleus |
|
| 9 |
EBI-751409,EBI-5666657 |
GPATCH2L |
|
| | | | |
.N/A |
.N/A |
.N/A |
|
|
| |
|
| EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
|
| |
|
| Body Sites | |
| Tissues | TPM* | |
|
| ascites | 50 | |
| blood | 8 | |
| bone marrow | 41 | |
| brain | 14 | |
| connective tissue | 6 | |
| embryonic tissue | 18 | |
| eye | 47 | |
| heart | 11 | |
| intestine | 12 | |
| kidney | 28 | |
| liver | 19 | |
| lung | 20 | |
| mammary gland | 39 | |
| mouth | 15 | |
| muscle | 37 | |
| nerve | 64 | |
| ovary | 9 | |
| pancreas | 4 | |
| placenta | 17 | |
| prostate | 15 | |
| skin | 42 | |
| spleen | 18 | |
| testis | 124 | |
| thymus | 12 | |
| thyroid | 21 | |
| trachea | 19 | |
| uterus | 25 | |
|
| Health State | |
| Tissues | TPM* | |
|
| normal | 23 | |
| breast (mammary gland) tumor | 64 | |
| colorectal tumor | 17 | |
| gastrointestinal tumor | 16 | |
| germ cell tumor | 60 | |
| glioma | 46 | |
| head and neck tumor | 7 | |
| kidney tumor | 14 | |
| liver tumor | 31 | |
| lung tumor | 19 | |
| lymphoma | 55 | |
| ovarian tumor | 13 | |
| pancreatic tumor | 9 | |
| primitive neuroectodermal tumor of the CNS | 15 | |
| prostate cancer | 28 | |
| retinoblastoma | 129 | |
| skin tumor | 63 | |
| soft tissue/muscle tissue tumor | 7 | |
| uterine tumor | 55 | |
|
| Developmental Stage | |
| Tissues | TPM* | |
|
| adult | 23 | |
| blastocyst | 32 | |
| fetus | 46 | |
| juvenile | 17 | |
|
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
| |
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| Expression level of Protein (ref. Human Protein Atlas) |
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| RNA-Seq. | |
| Tissues | FPKM | |
|
| adipose tissue | 3.4 | |
| adrenal gland | 2.7 | |
| appendix | 3.1 | |
| bone marrow | 2.9 | |
| cerebral cortex | 3.2 | |
| colon | 3.3 | |
| duodenum | 2.3 | |
| esophagus | 3.4 | |
| gallbladder | 3.8 | |
| heart muscle | 2.1 | |
| kidney | 3.2 | |
| liver | 2.1 | |
| lung | 5.7 | |
| lymph node | 4 | |
| ovary | 4.9 | |
| pancreas | 2.2 | |
| placenta | 3.1 | |
| prostate | 8.2 | |
| salivary gland | 2.1 | |
| skin | 3.3 | |
| small intestine | 2.5 | |
| spleen | 6 | |
| stomach | 2.8 | |
| testis | 39.7 | |
| thyroid gland | 5.3 | |
| urinary bladder | 3.4 | |
|
| Cancer | |
| Tumor | Number of patients and Staining levels | |
| breast cancer | |
| carcinoid | |
| cervical cancer | |
| colorectal cancer | |
| endometrial cancer | |
| glioma | |
| head and neck cancer | |
| liver cancer | |
| lung cancer | |
| lymphoma | |
| melanoma | |
| ovarian cancer | |
| pancreatic cancer | |
| prostate cancer | |
| renal cancer | |
| skin cancer | |
| stomach cancer | |
| testis cancer | |
| thyroid cancer | |
| urothelial cancer | |
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| RNA-seq colour codes |
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|
Highly expressed RNAs (FPKM >50) | |
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Moderately expressed RNAs (50> FPKM >10) | |
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Lower expressed RNAs (10> FPKM >1) | |
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The lowest expressed RNAs (FPKM value of 0 or 1) |
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| Staining level colour codes |
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Highly expressed protein | |
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Moderately expressed protein | |
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Lower expressed protein | |
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Not Detected |
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> Protein (NX_Q8WTR7)