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> Protein (NX_Q8WTR7)
Protein (NX_Q8WTR7)
Protein
Gene SymbolZNF473 to neXtProt (NX_Q8WTR7)
DescriptionZinc finger protein 473
Chromosome19
Location19q13.33 (50528971 ~ 50556671) to Ensembl
Sequene Features : Isoforms 1, Variants 118, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mRNA 3'-end processing
.gene expression
.histone mRNA metabolic process
  + 4 more...
.metal ion binding
.DNA binding
.Cajal body
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 118 0
2014-09-19protein level
1 95 0
2014-05-27protein level
1 95 0
2014-02-25protein level
1 94 0
2013-12-09protein level
1 76 0
2013-11-01protein level
1 74 0
2013-09-12protein level
1 74 0
2013-08-17protein level
1 74 0
2013-07-15protein level
1 50 0
2013-06-11protein level
1 50 0
2013-02-12protein level
1 35 0
2012-12-20protein level
1 35 0
2012-10-30protein level
1 41 0
2012-10-07protein level
1 41 0
2012-08-24protein level
1 38 0
2012-07-28protein level
1 38 0
2012-06-08protein level
1 42 0
2012-05-07protein level
1 32 0
2012-04-10protein level
1 32 0
2012-01-13protein level
1 15 0
2011-12-20protein level
1 15 0
2011-11-11protein level
1 15 0
2011-08-23protein level
1 15 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8WTR7-1
39 0 4 100117.799
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-751409,EBI-1210440 ZSCAN12  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
2 EBI-751409,EBI-10177272 ZNF250  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
3 EBI-751409,EBI-750020 CLK2  
  .protein autophosphorylation
.negative regulation of gluconeogenesis
.regulation of RNA splicing
  + 3 more...
.ATP binding
.protein tyrosine kinase activity
.protein serine/threonine/tyrosine kinase activity
.protein serine/threonine kinase activity
.nuclear speck
.nucleoplasm
.nucleus
4 EBI-751409,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
5 EBI-751409,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
6 EBI-751409,EBI-10240849 ZNF792  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
7 EBI-751409,EBI-1051531 DHX57  
  .RNA processing .metal ion binding
.poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity
.mitochondrion
.nucleus
8 EBI-751409,EBI-8637627 AEN  
  .nucleic acid phosphodiester bond hydrolysis
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.response to ionizing radiation
.exonuclease activity
.nucleic acid binding
.nuclear membrane
.nucleolus
.nucleoplasm
.nucleus
9 EBI-751409,EBI-5666657 GPATCH2L  
  .N/A .N/A .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
blood8
bone marrow41
brain14
connective tissue6
embryonic tissue18
eye47
heart11
intestine12
kidney28
liver19
lung20
mammary gland39
mouth15
muscle37
nerve64
ovary9
pancreas4
placenta17
prostate15
skin42
spleen18
testis124
thymus12
thyroid21
trachea19
uterus25
Health State
TissuesTPM*
normal23
breast (mammary gland) tumor64
colorectal tumor17
gastrointestinal tumor16
germ cell tumor60
glioma46
head and neck tumor7
kidney tumor14
liver tumor31
lung tumor19
lymphoma55
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS15
prostate cancer28
retinoblastoma129
skin tumor63
soft tissue/muscle tissue tumor7
uterine tumor55
Developmental Stage
TissuesTPM*
adult23
blastocyst32
fetus46
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.4
adrenal gland2.7
appendix3.1
bone marrow2.9
cerebral cortex3.2
colon3.3
duodenum2.3
esophagus3.4
gallbladder3.8
heart muscle2.1
kidney3.2
liver2.1
lung5.7
lymph node4
ovary4.9
pancreas2.2
placenta3.1
prostate8.2
salivary gland2.1
skin3.3
small intestine2.5
spleen6
stomach2.8
testis39.7
thyroid gland5.3
urinary bladder3.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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