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> Protein (NX_Q8WU79)
Protein (NX_Q8WU79)
Protein
Gene SymbolSMAP2 to neXtProt (NX_Q8WU79)
DescriptionStromal membrane-associated protein 2
Chromosome1
Location1p34.2 (40810522 ~ 40888998) to Ensembl
Sequene Features : Isoforms 3, Variants 44, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .zinc ion binding
.GTPase activator activity
.cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 44 4
2014-09-19protein level
3 36 4
2014-05-27protein level
3 36 4
2014-02-25protein level
3 36 4
2013-12-09protein level
3 26 4
2013-11-01protein level
3 23 4
2013-09-12protein level
3 23 4
2013-08-17protein level
3 23 4
2013-07-15protein level
3 17 3
2013-06-11protein level
3 17 3
2013-02-12protein level
3 7 9
2012-12-20protein level
3 7 9
2012-10-30protein level
3 12 9
2012-10-07protein level
3 12 3
2012-08-24protein level
3 12 3
2012-07-28protein level
3 12 3
2012-06-08protein level
3 14 3
2012-05-07protein level
2 9 3
2012-04-10protein level
2 9 3
2012-01-13protein level
2 4 3
2011-12-20protein level
2 4 3
2011-11-11protein level
2 4 3
2011-08-23protein level
2 4 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8WU79-1
2 10 2 46754.6539
NX_Q8WU79-2
0 10 2 43461.0975
NX_Q8WU79-3
1 9 0 37672.1398
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2822515,EBI-7875264 DAB1  
  .lateral motor column neuron migration
.Golgi localization
.negative regulation of axonogenesis
  + 15 more...
.N/A .perinuclear region of cytoplasm
.apical part of cell
.neuronal cell body
  + 5 more...
2 EBI-2822515,EBI-724310 DAZAP2  
  .N/A .WW domain binding .cytoplasm
.nucleus
3 EBI-2822515,EBI-946029 C1orf94  
  .N/A .N/A .N/A
4 EBI-2822515,EBI-7957930 FAM168A  
  .N/A .N/A .N/A
5 EBI-2822515,EBI-716006 MAGED1  
  .positive regulation of apoptotic signaling pathway
.extrinsic apoptotic signaling pathway in absence of ligand
.extrinsic apoptotic signaling pathway
  + 15 more...
.transcription coactivator activity .protein complex
.plasma membrane
.cytoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder66
blood286
bone27
brain62
cervix20
connective tissue40
embryonic tissue14
eye28
heart11
intestine38
kidney18
larynx85
liver24
lung59
lymph22
lymph node33
mammary gland52
mouth30
muscle37
nerve128
ovary19
pancreas9
parathyroid97
pharynx24
pituitary gland60
placenta24
prostate42
skin14
spleen187
stomach10
testis48
thymus200
thyroid64
tonsil352
trachea77
umbilical cord145
uterus12
Health State
TissuesTPM*
normal55
breast (mammary gland) tumor64
cervical tumor28
chondrosarcoma72
colorectal tumor35
gastrointestinal tumor16
germ cell tumor18
glioma46
head and neck tumor52
kidney tumor14
leukemia116
liver tumor41
lung tumor77
lymphoma69
non-neoplasia41
pancreatic tumor9
primitive neuroectodermal tumor of the CNS47
prostate cancer67
retinoblastoma21
skin tumor23
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult55
blastocyst16
neonate96
fetus44
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue53.2
adrenal gland23.4
appendix133.2
bone marrow46.5
cerebral cortex52.9
colon31.9
duodenum15.7
esophagus27.5
gallbladder50.6
heart muscle13
kidney9.8
liver28.4
lung27.1
lymph node189.3
ovary16.7
pancreas11.5
placenta28
prostate15.6
salivary gland12.3
skin17.2
small intestine30.3
spleen125.4
stomach38.9
testis18.1
thyroid gland15.8
urinary bladder46.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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