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> Protein (NX_Q8WUD1)
Protein (NX_Q8WUD1)
Protein
Gene SymbolRAB2B to neXtProt (NX_Q8WUD1)
DescriptionRas-related protein Rab-2B
Chromosome14
Location14q11.2 (21927179 ~ 21945132) to Ensembl
Sequene Features : Isoforms 2, Variants 22, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of exocytosis
.Rab protein signal transduction
.vesicle-mediated transport
  + 2 more...
.GTP binding
.GTPase activity
.extracellular exosome
.plasma membrane
.endoplasmic reticulum membrane
.Golgi membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 22 2
2014-09-19protein level
2 17 2
2014-05-27protein level
1 17 3
2014-02-25protein level
1 17 3
2013-12-09protein level
1 12 3
2013-11-01protein level
1 10 2
2013-09-12protein level
1 10 2
2013-08-17protein level
1 10 2
2013-07-15protein level
1 6 2
2013-06-11protein level
1 6 2
2013-02-12protein level
1 3 2
2012-12-20protein level
1 3 2
2012-10-30protein level
1 5 2
2012-10-07protein level
1 5 2
2012-08-24protein level
1 3 2
2012-07-28protein level
1 3 2
2012-06-08protein level
1 4 2
2012-05-07protein level
1 4 2
2012-04-10protein level
1 4 2
2012-01-13protein level
1 4 2
2011-12-20protein level
1 4 2
2011-11-11protein level
1 4 2
2011-08-23protein level
1 4 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8WUD1-1
1 6 7 24199.0768
NX_Q8WUD1-2
0 6 3 16656.1345
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5542466,EBI-1046751 ICA1  
  .neurotransmitter transport .N/A .synaptic vesicle membrane
.secretory granule membrane
.transport vesicle membrane
  + 4 more...
2 EBI-5542466,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
3 EBI-5542466,EBI-10173507 ADAMTSL4  
  .cellular protein metabolic process
.post-translational protein modification
.positive regulation of apoptotic process
  + 4 more...
.metalloendopeptidase activity
.protease binding
.endoplasmic reticulum lumen
.interstitial matrix
4 EBI-5542466,EBI-2686288 FAM114A1  
  .N/A .N/A .cytoplasm
5 EBI-5542466,EBI-752049 FAM71C  
  .N/A .N/A .N/A
6 EBI-5542466,EBI-2548012 BLZF1  
  .Golgi to plasma membrane protein transport
.cell proliferation
.Golgi organization
  + 3 more...
.ubiquitin protein ligase binding
.enzyme binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.Golgi lumen
.cytoplasm
.nucleoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
bladder33
blood24
bone41
brain36
cervix20
connective tissue20
embryonic tissue42
eye33
heart55
intestine34
kidney9
larynx42
liver24
lung35
lymph node33
mammary gland46
muscle18
nerve64
ovary29
pancreas42
pharynx49
pituitary gland60
placenta28
prostate47
skin28
testis27
thymus25
thyroid21
trachea19
uterus17
vascular19
Health State
TissuesTPM*
normal34
breast (mammary gland) tumor10
chondrosarcoma72
colorectal tumor53
gastrointestinal tumor8
germ cell tumor30
glioma27
head and neck tumor22
kidney tumor14
leukemia42
liver tumor10
lung tumor19
lymphoma13
non-neoplasia41
ovarian tumor39
pancreatic tumor28
primitive neuroectodermal tumor of the CNS7
prostate cancer67
skin tumor23
soft tissue/muscle tissue tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult42
embryoid body57
fetus26
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12
adrenal gland15
appendix11.5
bone marrow15.3
cerebral cortex13.7
colon10.8
duodenum9.6
esophagus10.1
gallbladder14.2
heart muscle10.9
kidney11.5
liver6.8
lung14.6
lymph node12.5
ovary16.4
pancreas4.3
placenta13.4
prostate15.7
salivary gland7.1
skin12.3
small intestine8.7
spleen11.4
stomach10.6
testis14.4
thyroid gland14.9
urinary bladder15.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607466, gene) Ras-associated protein rab2b; RAB2BOMIM


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