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> Protein (NX_Q8WUF5)
Protein (NX_Q8WUF5)
Protein
Gene SymbolPPP1R13L to neXtProt (NX_Q8WUF5)
DescriptionRelA-associated inhibitor
Chromosome19
Location19q13.32 (45882892 ~ 45909607) to Ensembl
Sequene Features : Isoforms 1, Variants 81, PTMs 30 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cardiac muscle contraction
.multicellular organismal homeostasis
.hair cycle
  + 8 more...
.identical protein binding
.transcription factor binding
.transcription corepressor activity
.intercellular bridge
.cell junction
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 81 30
2014-09-19protein level
1 57 30
2014-05-27protein level
1 57 30
2014-02-25protein level
1 57 26
2013-12-09protein level
1 43 26
2013-11-01protein level
1 40 25
2013-09-12protein level
1 40 25
2013-08-17protein level
1 40 25
2013-07-15protein level
1 26 25
2013-06-11protein level
1 26 25
2013-02-12protein level
1 7 22
2012-12-20protein level
1 9 22
2012-10-30protein level
1 10 22
2012-10-07protein level
1 10 22
2012-08-24protein level
1 7 22
2012-07-28protein level
2 7 22
2012-06-08protein level
2 9 22
2012-05-07protein level
2 9 22
2012-04-10protein level
2 9 22
2012-01-13protein level
2 9 22
2011-12-20protein level
2 9 22
2011-11-11protein level
2 9 19
2011-08-23protein level
2 9 19
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8WUF5-1
38 0 0 89035.4915
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5550163,EBI-366083 TP53  
  .positive regulation of intrinsic apoptotic signaling pathway
.positive regulation of reactive oxygen species metabolic process
.negative regulation of reactive oxygen species metabolic process
  + 99 more...
.protein phosphatase 2A binding
.chaperone binding
.protein N-terminus binding
  + 27 more...
.protein complex
.PML body
.nuclear matrix
  + 11 more...
2 EBI-5550163,EBI-357253 PPP1CA  
  .positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
.cell division
.branching morphogenesis of an epithelial tube
  + 15 more...
.metal ion binding
.ribonucleoprotein complex binding
.phosphatase activity
.protein serine/threonine phosphatase activity
.PTW/PP1 phosphatase complex
.MLL5-L complex
.extracellular exosome
  + 10 more...
3 EBI-5550163,EBI-447295 EP300  
  .negative regulation of protein stabilization
.regulation of cellular response to heat
.regulation of tubulin deacetylation
  + 40 more...
.pre-mRNA intronic binding
.androgen receptor binding
.nuclear hormone receptor binding
  + 17 more...
.cytoplasm
.transcription factor complex
.nucleoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
bone55
brain2
connective tissue33
embryonic tissue46
eye47
heart55
intestine47
kidney9
liver9
lung17
mammary gland79
mouth15
nerve64
pancreas32
pharynx24
placenta35
prostate5
skin47
spleen56
stomach94
testis6
thyroid21
trachea19
uterus73
Health State
TissuesTPM*
normal17
bladder carcinoma56
breast (mammary gland) tumor42
chondrosarcoma24
colorectal tumor53
gastrointestinal tumor75
germ cell tumor30
glioma18
head and neck tumor14
liver tumor10
lung tumor9
non-neoplasia31
pancreatic tumor38
retinoblastoma43
skin tumor47
soft tissue/muscle tissue tumor15
uterine tumor166
Developmental Stage
TissuesTPM*
adult33
embryoid body14
blastocyst65
fetus19
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.5
adrenal gland10.2
appendix3.5
cerebral cortex2.1
colon8.4
duodenum7.2
esophagus43.2
gallbladder7.5
heart muscle39.2
kidney8.5
liver3.3
lung23.5
lymph node3.1
ovary4.8
pancreas11.3
placenta35.1
prostate18.9
salivary gland20.9
skin167.1
small intestine6.6
spleen6.2
stomach10.7
testis2.7
thyroid gland7.9
urinary bladder19.1
Tissues
TissuesExpression level
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexHigh
cervix, uterineLow
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Low
epididymisHigh
fallopian tubeMedium
gallbladderLow
heart muscleMedium
hippocampusHigh
kidneyLow
lateral ventricleMedium
liverMedium
lungHigh
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasHigh
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
seminal vesicleLow
skin 1Medium
skin 2High
small intestineMedium
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandHigh
tonsilMedium
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607463, gene) Protein phosphatase 1, regulatory subunit 13-like; PPP1R13LOMIM


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