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> Protein (NX_Q8WVK2)
Protein (NX_Q8WVK2)
Protein
Gene SymbolSNRNP27 to neXtProt (NX_Q8WVK2)
DescriptionU4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
Chromosome2
Location2p13.3 (70120692 ~ 70132707) to Ensembl
Sequene Features : Isoforms 1, Variants 21, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.RNA splicing
.mRNA processing
.nucleic acid binding .precatalytic spliceosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 21 6
2014-09-19protein level
1 15 6
2014-05-27protein level
1 15 6
2014-02-25protein level
1 15 6
2013-12-09protein level
1 14 6
2013-11-01protein level
1 14 6
2013-09-12protein level
1 14 6
2013-08-17protein level
1 14 6
2013-07-15protein level
1 10 6
2013-06-11protein level
1 10 6
2013-02-12protein level
1 4 8
2012-12-20protein level
1 4 8
2012-10-30protein level
1 4 8
2012-10-07protein level
1 4 10
2012-08-24protein level
1 4 10
2012-07-28protein level
1 4 10
2012-06-08protein level
1 4 10
2012-05-07protein level
1 3 10
2012-04-10protein level
1 3 10
2012-01-13protein level
1 2 10
2011-12-20protein level
1 2 10
2011-11-11protein level
1 2 8
2011-08-23protein level
1 2 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8WVK2-1
6 0 0 18848.816
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2512550,EBI-593303 SRPK2  
  .regulation of mRNA splicing, via spliceosome
.positive regulation of cell cycle
.innate immune response
  + 12 more...
.14-3-3 protein binding
.poly(A) RNA binding
.ATP binding
  + 2 more...
.cytoplasm
.nucleolus
.nucleoplasm
.nucleus
2 EBI-2512550,EBI-2555370 CHERP  
  .positive regulation of NFAT protein import into nucleus
.release of sequestered calcium ion into cytosol
.negative regulation of cell proliferation
  + 3 more...
.poly(A) RNA binding
.ion channel binding
.perinuclear region of cytoplasm
.sarcoplasmic reticulum membrane
.membrane
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
bladder133
blood32
bone55
bone marrow205
brain64
cervix41
connective tissue20
ear62
embryonic tissue61
eye90
heart33
intestine21
kidney80
larynx85
liver43
lung59
lymph22
lymph node44
mammary gland13
muscle56
ovary39
pancreas28
pharynx73
pituitary gland121
placenta52
prostate36
salivary gland542
skin109
spleen37
stomach31
testis48
thymus12
uterus38
vascular19
Health State
TissuesTPM*
normal44
bladder carcinoma113
breast (mammary gland) tumor21
chondrosarcoma60
colorectal tumor8
gastrointestinal tumor42
germ cell tumor98
glioma177
head and neck tumor29
kidney tumor87
leukemia137
liver tumor52
lung tumor9
lymphoma27
non-neoplasia10
ovarian tumor26
pancreatic tumor9
primitive neuroectodermal tumor of the CNS23
prostate cancer28
retinoblastoma64
skin tumor127
soft tissue/muscle tissue tumor23
uterine tumor44
Developmental Stage
TissuesTPM*
adult37
embryoid body71
blastocyst16
fetus23
infant42
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue32.8
adrenal gland41
appendix31.8
bone marrow32.7
cerebral cortex40.1
colon25.1
duodenum24.9
esophagus26.7
gallbladder28.4
heart muscle38
kidney27.1
liver18
lung27.8
lymph node42.9
ovary26.3
pancreas11.9
placenta35.3
prostate34.4
salivary gland20.5
skin19.8
small intestine26.8
spleen29.5
stomach25.2
testis25.4
thyroid gland32.5
urinary bladder30.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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