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> Protein (NX_Q8WVZ9)
Protein (NX_Q8WVZ9)
Protein
Gene SymbolKBTBD7 to neXtProt (NX_Q8WVZ9)
DescriptionKelch repeat and BTB domain-containing protein 7
Chromosome13
Location13q14.11 (41763969 ~ 41768702) to Ensembl
Sequene Features : Isoforms 1, Variants 69, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 69 8
2014-09-19protein level
1 55 8
2014-05-27protein level
1 55 10
2014-02-25protein level
1 56 10
2013-12-09protein level
1 44 10
2013-11-01protein level
1 42 10
2013-09-12protein level
1 42 10
2013-08-17protein level
1 42 10
2013-07-15protein level
1 24 2
2013-06-11protein level
1 24 2
2013-02-12protein level
1 10 0
2012-12-20protein level
1 12 0
2012-10-30protein level
1 13 0
2012-10-07protein level
1 13 0
2012-08-24protein level
1 5 0
2012-07-28protein level
1 5 0
2012-06-08protein level
1 8 0
2012-05-07protein level
1 8 0
2012-04-10protein level
1 8 0
2012-01-13protein level
1 4 0
2011-12-20protein level
1 4 0
2011-11-11protein level
1 4 0
2011-08-23protein level
1 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8WVZ9-1
20 0 14 77113.635
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-473695,EBI-712001 GABARAP  
  .membrane fusion
.nucleophagy
.extrinsic apoptotic signaling pathway via death domain receptors
  + 5 more...
.GABA receptor binding
.beta-tubulin binding
.microtubule binding
.perinuclear region of cytoplasm
.cell body
.cytoplasmic vesicle
  + 13 more...
2 EBI-473695,EBI-720116 GABARAPL2  
  .negative regulation of proteasomal protein catabolic process
.membrane fusion
.nucleophagy
  + 7 more...
.ATPase binding
.GABA receptor binding
.beta-tubulin binding
  + 2 more...
.cytoplasmic vesicle
.extrinsic component of membrane
.cytosol
  + 7 more...
3 EBI-473695,EBI-713786 PHC2  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 2 more...
.identical protein binding
.zinc ion binding
.DNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 2 more...
4 EBI-473695,EBI-2603996 MAP1LC3C  
  .membrane fusion
.nucleophagy
.cellular response to nitrogen starvation
  + 2 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 6 more...
5 EBI-473695,EBI-373144 MAP1LC3B  
  .regulation of mitochondrion degradation
.membrane fusion
.nucleophagy
  + 3 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 9 more...
6 EBI-473695,EBI-746969 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood8
bone marrow20
brain54
connective tissue6
embryonic tissue14
heart22
kidney4
liver19
lung29
mammary gland13
mouth90
pancreas18
placenta35
prostate5
spleen18
testis27
thymus37
thyroid21
trachea19
uterus12
vascular19
Health State
TissuesTPM*
normal27
breast (mammary gland) tumor21
gastrointestinal tumor8
germ cell tumor15
head and neck tumor44
liver tumor31
non-neoplasia10
pancreatic tumor9
primitive neuroectodermal tumor of the CNS31
prostate cancer9
uterine tumor11
Developmental Stage
TissuesTPM*
adult12
blastocyst16
fetus59
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.7
adrenal gland4.4
appendix3.2
bone marrow2.8
cerebral cortex6.8
colon3.5
duodenum3.7
esophagus2.6
gallbladder2.5
heart muscle3.8
kidney5.3
liver3.6
lung3.2
lymph node4.3
ovary5.9
pancreas2.1
placenta4.2
prostate5.8
salivary gland4.2
skin3
small intestine2.9
spleen4
stomach4.4
testis4.2
thyroid gland6.6
urinary bladder4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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