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> Protein (NX_Q8WWB3)
Protein (NX_Q8WWB3)
Protein
Gene SymbolDYDC1 to neXtProt (NX_Q8WWB3)
DescriptionDPY30 domain-containing protein 1
Chromosome10
Location10q23.1 (82095861 ~ 82116511) to Ensembl
Sequene Features : Isoforms 2, Variants 26, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 26 0
2014-09-19protein level
1 16 0
2014-05-27protein level
1 16 0
2014-02-25protein level
1 16 0
2013-12-09protein level
1 14 0
2013-11-01protein level
1 13 0
2013-09-12protein level
1 13 0
2013-08-17protein level
1 13 0
2013-07-15protein level
1 9 0
2013-06-11protein level
1 9 0
2013-02-12protein level
1 6 0
2012-12-20protein level
1 5 0
2012-10-30protein level
1 8 0
2012-10-07protein level
1 8 0
2012-08-24protein level
1 6 0
2012-07-28protein level
1 6 0
2012-06-08protein level
1 6 0
2012-05-07protein level
1 6 0
2012-04-10protein level
1 6 0
2012-01-13protein level
1 1 0
2011-12-20protein level
1 1 0
2011-11-11protein level
1 1 0
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8WWB3-1
1 10 0 20879.4814
NX_Q8WWB3-2
1 10 0 21780.8231
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-740680,EBI-346930 PIK3R2  
  .regulation of small GTPase mediated signal transduction
.leukocyte migration
.T cell receptor signaling pathway
  + 25 more...
.protein heterodimerization activity
.1-phosphatidylinositol-3-kinase regulator activity
.receptor tyrosine kinase binding
.protein phosphatase binding
.phosphatidylinositol 3-kinase complex
.cytosol
.nucleus
2 EBI-740680,EBI-707554 TXNDC9  
  .cell redox homeostasis .N/A .midbody
.centrosome
.cytoplasm
.nucleus
3 EBI-740680,EBI-1757866 MOS  
  .negative regulation of metaphase/anaphase transition of meiotic cell cycle
.establishment of meiotic spindle orientation
.protein autophosphorylation
  + 6 more...
.ATP binding
.MAP kinase kinase kinase activity
.protein serine/threonine kinase activity
.cytoplasm
4 EBI-740680,EBI-395261 CCNC  
  .positive regulation of transcription from RNA polymerase II promoter
.gene expression
.Notch signaling pathway
  + 4 more...
.N/A .mediator complex
.nucleoplasm
5 EBI-740680,EBI-740667 NME5  
  .negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
.cilium assembly
.ventricular system development
  + 7 more...
.ATP binding
.nucleoside diphosphate kinase activity
.sperm flagellum
.intracellular
6 EBI-740680,EBI-10181988 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
7 EBI-740680,EBI-3439227 ZGPAT  
  .negative regulation of transcription, DNA-templated
.negative regulation of epidermal growth factor-activated receptor activity
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.nucleus
8 EBI-740680,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
9 EBI-740680,EBI-740781 TCHP  
  .negative regulation of cell growth
.apoptotic process
.N/A .apical cortex
.keratin filament
.plasma membrane
  + 3 more...
10 EBI-740680,EBI-749118 WAC  
  .histone H2B conserved C-terminal lysine ubiquitination
.positive regulation of transcription, DNA-templated
.G1 DNA damage checkpoint
  + 5 more...
.chromatin binding
.RNA polymerase II core binding
.nuclear speck
.spliceosomal complex
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain2
testis29
Health State
TissuesTPM*
normal2
Developmental Stage
TissuesTPM*
adult1
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
lung1.3
testis88.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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