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> Protein (NX_Q8WWL2)
Protein (NX_Q8WWL2)
Protein
Gene SymbolSPIRE2 to neXtProt (NX_Q8WWL2)
DescriptionProtein spire homolog 2
Chromosome16
Location16q24.3 (89884587 ~ 89937727) to Ensembl
Sequene Features : Isoforms 4, Variants 81, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.formin-nucleated actin cable assembly
.establishment of meiotic spindle localization
.intracellular transport
  + 6 more...
.N/A .perinuclear region of cytoplasm
.cleavage furrow
.cytoplasmic vesicle membrane
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 81 3
2014-09-19protein level
4 69 3
2014-05-27protein level
4 69 3
2014-02-25protein level
4 69 3
2013-12-09protein level
4 54 3
2013-11-01protein level
4 51 3
2013-09-12protein level
4 51 3
2013-08-17protein level
4 51 3
2013-07-15protein level
4 39 3
2013-06-11protein level
4 39 3
2013-02-12protein level
4 18 8
2012-12-20protein level
4 18 8
2012-10-30protein level
4 19 8
2012-10-07protein level
4 19 2
2012-08-24protein level
4 19 2
2012-07-28protein level
4 18 2
2012-06-08protein level
4 23 2
2012-05-07protein level
4 21 2
2012-04-10protein level
4 21 2
2012-01-13protein level
4 4 2
2011-12-20protein level
4 13 2
2011-11-11protein level
4 13 2
2011-08-23protein level
4 13 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8WWL2-1
0 31 0 79620.0014
NX_Q8WWL2-2
1 28 0 74286.2354
NX_Q8WWL2-3
3 26 0 74584.5834
NX_Q8WWL2-4
2 22 0 65332.9634
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain11
cervix41
embryonic tissue18
eye9
intestine21
kidney4
liver14
lung5
mammary gland26
pancreas23
placenta38
skin9
stomach20
testis2
thyroid21
uterus8
Health State
TissuesTPM*
normal13
breast (mammary gland) tumor21
cervical tumor57
colorectal tumor26
glioma27
kidney tumor14
non-neoplasia10
pancreatic tumor47
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult12
blastocyst48
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.4
adrenal gland2.9
appendix2.4
cerebral cortex6.5
colon16.4
duodenum11.2
esophagus1.7
gallbladder3.6
kidney2.6
liver1.8
lung4.1
ovary1.4
placenta14.8
prostate4.8
salivary gland2.1
skin2.2
small intestine17.3
spleen1.2
stomach22.5
testis8
thyroid gland5.4
urinary bladder5.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609217, gene) Spire, drosophila, homolog of, 2; SPIRE2OMIM


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