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> Protein (NX_Q8WXA3)
Protein (NX_Q8WXA3)
Protein
Gene SymbolRUFY2 to neXtProt (NX_Q8WXA3)
DescriptionRUN and FYVE domain-containing protein 2
Chromosome10
Location10q21.3 (70100864 ~ 70167051) to Ensembl
Sequene Features : Isoforms 5, Variants 75, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .metal ion binding .nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 75 3
2014-09-19protein level
5 53 3
2014-05-27protein level
5 53 3
2014-02-25protein level
4 52 3
2013-12-09protein level
4 38 3
2013-11-01protein level
4 38 3
2013-09-12protein level
4 38 3
2013-08-17protein level
4 38 3
2013-07-15protein level
4 25 3
2013-06-11protein level
4 25 3
2013-02-12protein level
4 7 3
2012-12-20protein level
4 6 3
2012-10-30protein level
4 11 3
2012-10-07protein level
4 11 1
2012-08-24protein level
4 7 1
2012-07-28protein level
4 7 1
2012-06-08protein level
4 1 1
2012-05-07protein level
4 1 1
2012-04-10protein level
4 1 1
2012-01-13protein level
4 1 1
2011-12-20protein level
4 1 1
2011-11-11protein level
4 1 0
2011-08-23protein level
4 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q8WXA3-1
2 29 2 75007.6688
NX_Q8WXA3-2
0 29 2 69965.9598
NX_Q8WXA3-3
2 29 2 74034.0244
NX_Q8WXA3-4
1 21 2 46106.6196
NX_Q8WXA3-5
0 19 2 43692.5456
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
bladder33
blood8
bone83
bone marrow41
brain34
connective tissue33
embryonic tissue9
esophagus99
eye19
heart33
intestine21
kidney18
liver4
lung5
lymph node33
mammary gland6
mouth60
muscle47
nerve128
ovary9
pancreas28
placenta24
skin14
testis20
thymus37
thyroid42
trachea38
uterus17
vascular58
Health State
TissuesTPM*
normal27
bladder carcinoma56
breast (mammary gland) tumor10
chondrosarcoma72
colorectal tumor8
esophageal tumor115
germ cell tumor11
head and neck tumor22
kidney tumor29
non-neoplasia10
ovarian tumor39
pancreatic tumor9
primitive neuroectodermal tumor of the CNS31
skin tumor7
soft tissue/muscle tissue tumor31
uterine tumor33
Developmental Stage
TissuesTPM*
adult24
fetus28
infant85
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.5
adrenal gland8.4
appendix6.2
bone marrow3.6
cerebral cortex24.2
colon6.2
duodenum4.7
esophagus7.8
gallbladder8.6
heart muscle4.5
kidney6.3
liver2.2
lung8.3
lymph node6.2
ovary12.7
pancreas3.5
placenta6.3
prostate10
salivary gland4.6
skin8.8
small intestine5.7
spleen6.7
stomach6.5
testis7
thyroid gland10.2
urinary bladder8.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610328, gene) Run and fyve domains-containing protein 2; RUFY2OMIM


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