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> Protein (NX_Q92539)
Protein (NX_Q92539)
Protein
Gene SymbolLPIN2 to neXtProt (NX_Q92539)
DescriptionPhosphatidate phosphatase LPIN2
Chromosome18
Location18p11.31 (2916992 ~ 3013313) to Ensembl
Sequene Features : Isoforms 1, Variants 102, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.glycerophospholipid biosynthetic process
.positive regulation of transcription from RNA polymerase II promoter
.small molecule metabolic process
  + 9 more...
.phosphatidate phosphatase activity
.transcription coactivator activity
.cytosol
.endoplasmic reticulum membrane
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 102 6
2014-09-19protein level
1 82 6
2014-05-27protein level
1 82 6
2014-02-25protein level
1 81 6
2013-12-09protein level
1 61 6
2013-11-01protein level
1 60 6
2013-09-12protein level
1 60 6
2013-08-17protein level
1 60 6
2013-07-15protein level
1 42 6
2013-06-11protein level
1 42 6
2013-02-12protein level
1 23 5
2012-12-20protein level
1 22 5
2012-10-30protein level
1 27 5
2012-10-07protein level
1 27 5
2012-08-24protein level
1 20 5
2012-07-28protein level
1 20 5
2012-06-08protein level
1 20 5
2012-05-07protein level
1 20 5
2012-04-10protein level
1 20 5
2012-01-13protein level
1 8 5
2011-12-20protein level
1 8 5
2011-11-11protein level
1 8 5
2011-08-23protein level
1 8 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q92539-1
38 0 2 99336.9267
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
blood81
bone83
bone marrow20
brain68
connective tissue53
ear62
embryonic tissue14
eye86
heart122
intestine73
kidney99
liver146
lung53
lymph node111
muscle84
nerve128
ovary39
pancreas28
pharynx24
pituitary gland121
placenta42
prostate63
skin4
testis36
thymus37
thyroid64
uterus56
vascular58
Health State
TissuesTPM*
normal74
chondrosarcoma120
colorectal tumor35
gastrointestinal tumor16
germ cell tumor49
glioma139
head and neck tumor22
kidney tumor29
leukemia31
liver tumor83
lung tumor19
non-neoplasia93
ovarian tumor52
pancreatic tumor57
primitive neuroectodermal tumor of the CNS7
prostate cancer28
retinoblastoma21
soft tissue/muscle tissue tumor39
uterine tumor66
Developmental Stage
TissuesTPM*
adult67
embryoid body14
blastocyst32
fetus127
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.3
adrenal gland9.9
appendix20.8
bone marrow11.8
cerebral cortex18.5
colon16.2
duodenum57.4
esophagus10.8
gallbladder30
heart muscle6
kidney30.3
liver89.6
lung22
lymph node24.4
ovary14.8
pancreas8.5
placenta19.1
prostate9.5
salivary gland5.6
skin3
small intestine36.1
spleen18.6
stomach26.2
testis30.3
thyroid gland15.4
urinary bladder13.6
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumHigh
endometrium 1Medium
endometrium 2High
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleLow
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverHigh
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaLow
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Low
skin 2Low
small intestineHigh
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1High
stomach 2High
testisHigh
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605519, gene) Lipin 2; LPIN2OMIM
2(#609628, phenotype) Majeed syndromeOMIM


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