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> Protein (NX_Q92567)
Protein (NX_Q92567)
Protein
Gene SymbolFAM168A to neXtProt (NX_Q92567)
DescriptionProtein FAM168A
Chromosome11
Location11q13.4 (73111532 ~ 73309234) to Ensembl
Sequene Features : Isoforms 3, Variants 15, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 15 2
2014-09-19protein level
3 12 2
2014-05-27protein level
3 12 2
2014-02-25protein level
3 12 1
2013-12-09protein level
3 9 1
2013-11-01protein level
3 9 1
2013-09-12protein level
3 9 1
2013-08-17protein level
3 9 1
2013-07-15protein level
3 5 0
2013-06-11protein level
3 5 0
2013-02-12protein level
3 0 6
2012-12-20protein level
3 0 6
2012-10-30protein level
3 0 6
2012-10-07protein level
3 0 2
2012-08-24protein level
3 0 2
2012-07-28protein level
3 0 2
2012-06-08protein level
3 0 2
2012-05-07protein level
3 2 2
2012-04-10protein level
3 2 2
2012-01-13protein level
3 2 2
2011-12-20protein level
3 2 2
2011-11-11protein level
3 2 2
2011-08-23protein level
3 2 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q92567-1
1 8 0 26167.4731
NX_Q92567-2
0 9 0 25044.9625
NX_Q92567-3
1 4 0 13776.4797
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-7957930,EBI-2559305 VPS37C  
  .intracellular transport of virus
.membrane organization
.viral protein processing
  + 5 more...
.calcium-dependent protein binding .extracellular exosome
.late endosome membrane
.endosome membrane
.ESCRT I complex
2 EBI-7957930,EBI-744674 SS18L1  
  .positive regulation of dendrite morphogenesis
.positive regulation of transcription, DNA-templated
.chromatin modification
  + 2 more...
.N/A .nBAF complex
.nuclear body
.nucleus
  + 3 more...
3 EBI-7957930,EBI-7875264 DAB1  
  .lateral motor column neuron migration
.Golgi localization
.negative regulation of axonogenesis
  + 15 more...
.N/A .perinuclear region of cytoplasm
.apical part of cell
.neuronal cell body
  + 5 more...
4 EBI-7957930,EBI-10172814 PRR20C  
  .N/A .N/A .N/A
5 EBI-7957930,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
6 EBI-7957930,EBI-1050671 UBE2V1  
  .protein K63-linked ubiquitination
.nucleotide-binding oligomerization domain containing signaling pathway
.positive regulation of NF-kappaB transcription factor activity
  + 22 more...
.ubiquitin protein ligase activity
.ubiquitin protein ligase binding
.ubiquitin-like protein transferase activity
.extracellular exosome
.protein complex
.UBC13-UEV1A complex
  + 5 more...
7 EBI-7957930,EBI-357849 TNIP1  
  .modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
.negative regulation of ERK1 and ERK2 cascade
.positive regulation of inflammatory response
  + 9 more...
.mitogen-activated protein kinase binding .cytoplasm
.nucleus
.intracellular
8 EBI-7957930,EBI-724310 DAZAP2  
  .N/A .WW domain binding .cytoplasm
.nucleus
9 EBI-7957930,EBI-744603 SF1  
  .negative regulation of nucleic acid-templated transcription
.regulation of steroid biosynthetic process
.negative regulation of smooth muscle cell proliferation
  + 7 more...
.poly(A) RNA binding
.zinc ion binding
.RNA binding
.transcription corepressor activity
.ribosome
.spliceosomal complex
.nucleoplasm
.nucleus
10 EBI-7957930,EBI-946029 C1orf94  
  .N/A .N/A .N/A
11 EBI-7957930,EBI-740376 DTX2  
  .protein ubiquitination
.Notch signaling pathway
.ligase activity
.zinc ion binding
.nuclear membrane
.cytoplasm
.nucleoplasm
12 EBI-7957930,EBI-529518 TAX1BP1  
  .innate immune response
.negative regulation of apoptotic process
.negative regulation of type I interferon production
  + 2 more...
.metal ion binding
.kinase binding
.extracellular exosome
.cytosol
13 EBI-7957930,EBI-1380492 UBASH3B  
  .negative regulation of platelet aggregation
.regulation of release of sequestered calcium ion into cytosol
.negative regulation of protein kinase activity
.protein tyrosine phosphatase activity .cytoplasm
.nucleus
14 EBI-7957930,EBI-2822515 SMAP2  
  .N/A .zinc ion binding
.GTPase activator activity
.cytoplasm
.nucleoplasm
15 EBI-7957930,EBI-740322 RBPMS  
  .positive regulation of SMAD protein import into nucleus
.positive regulation of pathway-restricted SMAD protein phosphorylation
.RNA processing
  + 2 more...
.poly(A) RNA binding
.poly(A) binding
.transcription coactivator activity
.nucleotide binding
.cytoplasm
.nucleoplasm
16 EBI-7957930,EBI-750730 OTULIN  
  .protein linear deubiquitination
.nucleotide-binding oligomerization domain containing 2 signaling pathway
.canonical Wnt signaling pathway
  + 4 more...
.cysteine-type peptidase activity
.ubiquitin-specific protease activity
.LUBAC complex
.cytoplasm
17 EBI-7957930,EBI-746259 OTUB2  
  .protein K48-linked deubiquitination
.protein K63-linked deubiquitination
.protein K11-linked deubiquitination
.protein deubiquitination
.ubiquitin-specific protease activity .nucleus
18 EBI-7957930,EBI-2515597 NAF1  
  .ribosome biogenesis
.rRNA processing
.pseudouridine synthesis
.poly(A) RNA binding
.RNA binding
.cytoplasm
.small nucleolar ribonucleoprotein complex
.nucleus
19 EBI-7957930,EBI-739890 KLHL42  
  .cell division
.proteasome-mediated ubiquitin-dependent protein catabolic process
.regulation of microtubule-based process
  + 2 more...
.N/A .Cul3-RING ubiquitin ligase complex
.spindle
.cytoplasm
20 EBI-7957930,EBI-10326419 R3HDM2  
  .N/A .poly(A) RNA binding .nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder33
blood16
bone83
brain70
cervix123
connective tissue40
ear62
embryonic tissue61
eye76
heart44
intestine43
kidney33
larynx85
liver29
lung20
lymph67
lymph node66
mammary gland13
mouth15
muscle28
nerve64
ovary118
pancreas14
pituitary gland60
placenta31
prostate10
skin23
spleen56
stomach20
testis22
thymus12
thyroid64
trachea57
uterus43
vascular19
Health State
TissuesTPM*
normal44
bladder carcinoma56
breast (mammary gland) tumor21
cervical tumor173
chondrosarcoma72
colorectal tumor44
gastrointestinal tumor25
germ cell tumor18
glioma177
head and neck tumor44
kidney tumor29
leukemia31
liver tumor41
lymphoma41
non-neoplasia20
ovarian tumor170
pancreatic tumor9
primitive neuroectodermal tumor of the CNS23
prostate cancer9
retinoblastoma43
skin tumor31
soft tissue/muscle tissue tumor47
uterine tumor22
Developmental Stage
TissuesTPM*
adult44
embryoid body114
blastocyst32
neonate32
fetus41
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue13.9
adrenal gland11.7
appendix12
bone marrow7.8
cerebral cortex57.3
colon10
duodenum8.1
esophagus11.1
gallbladder17.5
heart muscle11.1
kidney13.7
liver4.5
lung11
lymph node9.4
ovary18.7
pancreas5.8
placenta10.5
prostate13.1
salivary gland10.9
skin8.5
small intestine10.7
spleen10
stomach9
testis9
thyroid gland17
urinary bladder13.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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