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> Protein (NX_Q92636)
Protein (NX_Q92636)
Protein
Gene SymbolNSMAF to neXtProt (NX_Q92636)
DescriptionProtein FAN
Chromosome8
Location8q12.1 (59496063 ~ 59572403) to Ensembl
Sequene Features : Isoforms 2, Variants 106, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of apoptotic process
.intracellular signal transduction
.endosomal transport
  + 2 more...
.sphingomyelin phosphodiesterase activator activity
.phospholipid binding
.receptor signaling protein activity
.extrinsic component of membrane
.endomembrane system
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 106 2
2014-09-19protein level
2 81 2
2014-05-27protein level
2 81 3
2014-02-25protein level
2 80 3
2013-12-09protein level
2 63 3
2013-11-01protein level
2 63 3
2013-09-12protein level
2 63 3
2013-08-17protein level
2 63 3
2013-07-15protein level
2 45 2
2013-06-11protein level
2 45 2
2013-02-12protein level
2 23 0
2012-12-20protein level
2 22 0
2012-10-30protein level
2 31 0
2012-10-07protein level
2 31 0
2012-08-24protein level
2 23 0
2012-07-28protein level
2 23 0
2012-06-08protein level
2 24 0
2012-05-07protein level
2 24 0
2012-04-10protein level
2 24 0
2012-01-13protein level
2 10 0
2011-12-20protein level
2 10 0
2011-11-11protein level
2 10 0
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q92636-1
2 38 0 104305.6267
NX_Q92636-2
1 38 0 107245.0556
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2947053,EBI-712001 GABARAP  
  .membrane fusion
.nucleophagy
.extrinsic apoptotic signaling pathway via death domain receptors
  + 5 more...
.GABA receptor binding
.beta-tubulin binding
.microtubule binding
.perinuclear region of cytoplasm
.cell body
.cytoplasmic vesicle
  + 13 more...
2 EBI-2947053,EBI-748201 VASP  
  .protein homotetramerization
.T cell receptor signaling pathway
.cell junction assembly
  + 4 more...
.profilin binding .extracellular exosome
.filopodium membrane
.lamellipodium membrane
  + 6 more...
3 EBI-2947053,EBI-353944 ACTB  
  .platelet aggregation
.membrane organization
.'de novo' posttranslational protein folding
  + 17 more...
.nitric-oxide synthase binding
.identical protein binding
.Tat protein binding
  + 3 more...
.blood microparticle
.MLL5-L complex
.extracellular exosome
  + 16 more...
4 EBI-2947053,EBI-746969 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland30
bladder100
blood98
bone41
bone marrow41
brain35
cervix103
connective tissue13
ear62
embryonic tissue61
eye43
heart33
intestine34
kidney37
liver38
lung59
lymph node77
mammary gland33
mouth15
muscle28
nerve64
pancreas42
pharynx24
placenta95
prostate36
skin9
stomach10
testis25
thymus37
thyroid21
trachea77
uterus90
vascular38
Health State
TissuesTPM*
normal44
adrenal tumor79
bladder carcinoma170
breast (mammary gland) tumor21
cervical tumor28
chondrosarcoma36
colorectal tumor35
gastrointestinal tumor8
germ cell tumor60
glioma102
head and neck tumor22
kidney tumor29
leukemia84
liver tumor52
lung tumor9
lymphoma27
non-neoplasia62
pancreatic tumor38
primitive neuroectodermal tumor of the CNS31
prostate cancer28
retinoblastoma43
skin tumor15
soft tissue/muscle tissue tumor63
uterine tumor88
Developmental Stage
TissuesTPM*
adult54
embryoid body71
blastocyst32
neonate32
fetus55
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.7
adrenal gland16.5
appendix28.4
bone marrow10.6
cerebral cortex10.4
colon17.4
duodenum14.6
esophagus15.8
gallbladder17.1
heart muscle11.2
kidney9.6
liver5.1
lung16.7
lymph node29.7
ovary16.7
pancreas9.2
placenta15.7
prostate17.5
salivary gland10.5
skin26.4
small intestine14.6
spleen24.7
stomach15.7
testis9.3
thyroid gland19.3
urinary bladder22
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603043, gene) Neutral sphingomyelinase activation-associated factor; NSMAFOMIM


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