Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q92729)
Protein (NX_Q92729)
Protein
Gene SymbolPTPRU to neXtProt (NX_Q92729)
DescriptionReceptor-type tyrosine-protein phosphatase U
Chromosome1
Location1p35.3 (29563028 ~ 29653325) to Ensembl
Sequene Features : Isoforms 4, Variants 198, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.canonical Wnt signaling pathway
.response to glucocorticoid
.peptidyl-tyrosine dephosphorylation
  + 10 more...
.beta-catenin binding
.transmembrane receptor protein tyrosine phosphatase activity
.protein tyrosine phosphatase activity
.cell-cell junction
.integral component of plasma membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 198 7
2014-09-19protein level
4 151 7
2014-05-27protein level
4 151 7
2014-02-25protein level
4 148 7
2013-12-09protein level
4 114 7
2013-11-01protein level
4 110 7
2013-09-12protein level
4 110 7
2013-08-17protein level
4 110 7
2013-07-15protein level
4 85 7
2013-06-11protein level
4 85 7
2013-02-12protein level
4 42 24
2012-12-20protein level
4 41 24
2012-10-30protein level
4 46 24
2012-10-07protein level
4 46 6
2012-08-24protein level
4 41 6
2012-07-28protein level
4 41 6
2012-06-08protein level
4 52 6
2012-05-07protein level
4 39 6
2012-04-10protein level
4 39 6
2012-01-13protein level
4 28 6
2011-12-20protein level
4 28 6
2011-11-11protein level
4 28 6
2011-08-23protein level
4 28 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q92729-1
1 62 0 162319.5839
NX_Q92729-2
0 63 0 161004.025
NX_Q92729-3
0 63 0 160691.8351
NX_Q92729-4
1 61 0 161544.3364
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-7052301,EBI-1379503 KIT  
  .melanocyte adhesion
.melanocyte migration
.cellular response to thyroid hormone stimulus
  + 69 more...
.metal ion binding
.protein homodimerization activity
.cytokine binding
  + 5 more...
.mast cell granule
.integral component of membrane
.cytoplasmic side of plasma membrane
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
bone41
bone marrow41
brain15
cervix41
connective tissue13
embryonic tissue79
eye90
intestine8
kidney18
liver9
lung38
mammary gland6
mouth15
muscle47
ovary39
pancreas28
placenta21
prostate15
salivary gland49
skin9
stomach20
testis22
uterus34
Health State
TissuesTPM*
normal25
cervical tumor57
chondrosarcoma60
colorectal tumor17
gastrointestinal tumor33
germ cell tumor49
head and neck tumor14
kidney tumor43
lung tumor48
non-neoplasia10
ovarian tumor13
pancreatic tumor47
primitive neuroectodermal tumor of the CNS39
retinoblastoma86
uterine tumor66
Developmental Stage
TissuesTPM*
adult23
embryoid body114
blastocyst113
fetus19
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.5
adrenal gland4.8
appendix3.5
cerebral cortex5.8
colon3.3
duodenum1.7
esophagus4.6
gallbladder10.9
heart muscle4.3
kidney4.3
liver2.2
lung16.3
lymph node1.3
ovary12.8
pancreas7.2
placenta19.7
prostate11.2
salivary gland9.9
skin8.2
small intestine1.1
spleen4.6
stomach3.2
testis8
thyroid gland4.4
urinary bladder18.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602454, gene) Protein-tyrosine phosphatase, receptor-type, u; PTPRUOMIM
2papillary thyroidCGP


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2020 (C) Yonsei Proteome Research Center