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> Protein (NX_Q92832)
Protein (NX_Q92832)
Protein
Gene SymbolNELL1 to neXtProt (NX_Q92832)
DescriptionProtein kinase C-binding protein NELL1
Chromosome11
Location11p15.1 (20691117 ~ 21597227) to Ensembl
Sequene Features : Isoforms 2, Variants 221, PTMs 30 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of cyclin catabolic process
.positive regulation of osteoblast differentiation
.negative regulation of osteoblast proliferation
  + 4 more...
.calcium ion binding .perinuclear region of cytoplasm
.cytoplasm
.nuclear envelope
.extracellular region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 221 30
2014-09-19protein level
2 169 30
2014-05-27protein level
2 169 30
2014-02-25protein level
2 169 30
2013-12-09protein level
2 145 30
2013-11-01protein level
2 133 30
2013-09-12protein level
2 133 30
2013-08-17protein level
2 133 30
2013-07-15protein level
2 90 30
2013-06-11protein level
2 90 30
2013-02-12protein level
2 41 56
2012-12-20protein level
2 40 56
2012-10-30protein level
2 43 56
2012-10-07protein level
2 43 30
2012-08-24transcript level
2 42 30
2012-07-28transcript level
2 42 30
2012-06-08transcript level
2 47 30
2012-05-07transcript level
2 31 30
2012-04-10transcript level
2 31 30
2012-01-13transcript level
2 18 30
2011-12-20transcript level
2 18 30
2011-11-11transcript level
2 18 30
2011-08-23transcript level
2 18 30
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q92832-1
3 36 0 89573.6977
NX_Q92832-2
1 36 0 84319.5647
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-947754,EBI-723802 ATRAID  
  .negative regulation of cyclin catabolic process
.positive regulation of osteoblast differentiation
.negative regulation of osteoblast proliferation
  + 3 more...
.N/A .perinuclear region of cytoplasm
.integral component of membrane
.plasma membrane
.nuclear envelope
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
brain81
connective tissue6
kidney33
lung8
muscle56
pituitary gland60
prostate10
skin14
testis16
thymus12
trachea19
uterus8
Health State
TissuesTPM*
normal30
germ cell tumor3
kidney tumor43
lung tumor9
non-neoplasia20
primitive neuroectodermal tumor of the CNS23
prostate cancer9
skin tumor23
soft tissue/muscle tissue tumor31
uterine tumor11
Developmental Stage
TissuesTPM*
adult6
fetus91
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
cerebral cortex17
duodenum1.2
esophagus2.6
gallbladder1.3
kidney18.1
prostate4.3
stomach1.3
testis3.4
urinary bladder1.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602319, gene) Nel-like 1; NELL1OMIM


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