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> Protein (NX_Q92908)
Protein (NX_Q92908)
Protein
Gene SymbolGATA6 to neXtProt (NX_Q92908)
DescriptionTranscription factor GATA-6
Chromosome18
Location18q11.2 (19749404 ~ 19782491) to Ensembl
Sequene Features : Isoforms 2, Variants 57, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to BMP stimulus
.cellular response to hypoxia
.cellular response to gonadotropin stimulus
  + 33 more...
.transcription regulatory region DNA binding
.protein kinase binding
.zinc ion binding
  + 6 more...
.transcription factor complex
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 57 1
2014-09-19protein level
2 38 1
2014-05-27protein level
2 38 1
2014-02-25protein level
2 38 1
2013-12-09protein level
2 34 1
2013-11-01protein level
2 33 1
2013-09-12protein level
2 33 1
2013-08-17protein level
2 33 1
2013-07-15protein level
2 27 1
2013-06-11protein level
2 27 1
2013-02-12protein level
2 20 6
2012-12-20protein level
2 20 6
2012-10-30protein level
2 20 6
2012-10-07protein level
2 20 3
2012-08-24protein level
2 20 3
2012-07-28protein level
2 20 3
2012-06-08protein level
2 21 3
2012-05-07protein level
2 17 3
2012-04-10protein level
2 7 3
2012-01-13protein level
2 6 3
2011-12-20protein level
2 6 3
2011-11-11protein level
2 6 3
2011-08-23protein level
2 6 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q92908-1
6 13 2 59994.8123
NX_Q92908-2
1 13 2 45357.8154
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
ascites25
cervix61
connective tissue20
embryonic tissue46
heart33
intestine38
kidney4
liver34
lung32
ovary88
pancreas9
skin4
spleen18
stomach41
testis34
vascular19
Health State
TissuesTPM*
normal12
chondrosarcoma36
colorectal tumor8
gastrointestinal tumor25
germ cell tumor7
leukemia10
liver tumor52
non-neoplasia10
ovarian tumor91
primitive neuroectodermal tumor of the CNS15
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult2
embryoid body14
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4
adrenal gland36
appendix2.3
colon11.4
duodenum18
gallbladder11.7
heart muscle26.5
kidney1.3
liver5.4
lung10.7
lymph node1.9
ovary31.4
pancreas8.7
placenta4.8
prostate3
small intestine16.5
spleen10.3
stomach40.2
testis4.1
thyroid gland2.1
urinary bladder6.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#187500, phenotype) Tetralogy of fallot; TOFOMIM
2(#217095, phenotype) Conotruncal heart malformations; CTHMOMIM
3(#600001, phenotype) Pancreatic agenesis and congenital heart defects; PACHDOMIM
4(*601656, gene) Gata-binding protein 6; GATA6OMIM
5(#614474, phenotype) Atrioventricular septal defect 5; AVSD5OMIM
6(#614475, phenotype) Atrial septal defect 9; ASD9OMIM


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