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> Protein (NX_Q93008)
Protein (NX_Q93008)
Protein
Gene SymbolUSP9X to neXtProt (NX_Q93008)
DescriptionProbable ubiquitin carboxyl-terminal hydrolase FAF-X
ChromosomeX
LocationXp11.4 (40944888 ~ 41095832) to Ensembl
Sequene Features : Isoforms 2, Variants 190, PTMs 17 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of proteasomal protein catabolic process
.cell division
.axon extension
  + 16 more...
.co-SMAD binding
.cysteine-type peptidase activity
.ubiquitin-specific protease activity
.cysteine-type endopeptidase activity
.apical part of cell
.growth cone
.membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 190 17
2014-09-19protein level
2 134 17
2014-05-27protein level
2 134 30
2014-02-25protein level
2 131 30
2013-12-09protein level
2 117 30
2013-11-01protein level
2 117 10
2013-09-12protein level
2 117 11
2013-08-17protein level
2 117 11
2013-07-15protein level
2 59 10
2013-06-11protein level
2 59 10
2013-02-12protein level
2 14 16
2012-12-20protein level
2 14 16
2012-10-30protein level
2 21 16
2012-10-07protein level
2 21 8
2012-08-24protein level
2 19 8
2012-07-28protein level
2 19 8
2012-06-08protein level
2 17 8
2012-05-07protein level
2 17 8
2012-04-10protein level
2 17 8
2012-01-13protein level
2 19 8
2011-12-20protein level
2 19 8
2011-11-11protein level
2 19 7
2011-08-23protein level
2 19 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q93008-1
1 71 43 290276.8685
NX_Q93008-3
3 71 43 292092.8033
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-302524,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
2 EBI-302524,EBI-347263 SMAD4  
  .nephrogenic mesenchyme morphogenesis
.metanephric mesenchyme morphogenesis
.response to transforming growth factor beta
  + 49 more...
.R-SMAD binding
.I-SMAD binding
.metal ion binding
  + 9 more...
.SMAD protein complex
.activin responsive factor complex
.cytosol
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
ascites276
bladder167
blood24
bone153
bone marrow123
brain82
cervix185
connective tissue73
ear124
embryonic tissue192
eye110
heart134
intestine116
kidney118
liver77
lung331
lymph22
lymph node122
mammary gland119
mouth151
muscle112
nerve128
ovary68
pancreas65
parathyroid48
pharynx73
pituitary gland242
placenta158
prostate52
salivary gland49
skin90
spleen56
stomach104
testis153
thymus75
thyroid85
trachea77
uterus116
vascular58
Health State
TissuesTPM*
normal138
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor75
cervical tumor260
chondrosarcoma132
colorectal tumor204
gastrointestinal tumor143
germ cell tumor182
glioma27
head and neck tumor119
kidney tumor130
leukemia63
liver tumor135
lung tumor77
lymphoma41
non-neoplasia72
ovarian tumor91
pancreatic tumor76
primitive neuroectodermal tumor of the CNS47
prostate cancer19
retinoblastoma21
skin tumor55
soft tissue/muscle tissue tumor119
uterine tumor133
Developmental Stage
TissuesTPM*
adult156
embryoid body114
blastocyst341
fetus179
infant42
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.4
adrenal gland19.4
appendix21.5
bone marrow16.5
cerebral cortex20.1
colon21.3
duodenum15.9
esophagus16.9
gallbladder19.1
heart muscle15.3
kidney21.8
liver24.9
lung14
lymph node20.3
ovary17.4
pancreas10.1
placenta26.9
prostate13.1
salivary gland11.1
skin14.9
small intestine16.8
spleen15.1
stomach17.3
testis25.2
thyroid gland26
urinary bladder19.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300072, gene) Ubiquitin-specific protease 9, x chromosome; USP9XOMIM


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