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> Protein (NX_Q93062)
Protein (NX_Q93062)
Protein
Gene SymbolRBPMS to neXtProt (NX_Q93062)
DescriptionRNA-binding protein with multiple splicing
Chromosome8
Location8p12 (30241944 ~ 30429778) to Ensembl
Sequene Features : Isoforms 5, Variants 24, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of SMAD protein import into nucleus
.positive regulation of pathway-restricted SMAD protein phosphorylation
.RNA processing
  + 2 more...
.poly(A) RNA binding
.poly(A) binding
.transcription coactivator activity
.nucleotide binding
.cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 24 3
2014-09-19protein level
5 16 3
2014-05-27protein level
5 16 3
2014-02-25protein level
5 15 3
2013-12-09protein level
5 13 3
2013-11-01protein level
5 13 3
2013-09-12protein level
5 13 2
2013-08-17protein level
5 13 2
2013-07-15protein level
5 16 2
2013-06-11protein level
5 16 2
2013-02-12protein level
5 6 10
2012-12-20protein level
5 6 10
2012-10-30protein level
5 8 10
2012-10-07protein level
5 8 2
2012-08-24protein level
5 7 2
2012-07-28protein level
5 7 2
2012-06-08protein level
5 0 2
2012-05-07protein level
5 0 2
2012-04-10protein level
5 0 2
2012-01-13protein level
5 0 2
2011-12-20protein level
5 0 2
2011-11-11protein level
5 0 2
2011-08-23protein level
5 0 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q93062-1
1 6 2 21788.1738
NX_Q93062-2
2 5 2 22401.5332
NX_Q93062-3
2 5 2 24261.4233
NX_Q93062-4
1 5 2 15784.1768
NX_Q93062-5
0 6 2 17011.7669
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-740322,EBI-10171684 C14orf182  
  .N/A .N/A .N/A
2 EBI-740322,EBI-10171734 KRTAP23-1  
  .N/A .N/A .intermediate filament
3 EBI-740322,EBI-10173222 DCDC2B  
  .intracellular signal transduction .N/A .N/A
4 EBI-740322,EBI-2559305 VPS37C  
  .intracellular transport of virus
.membrane organization
.viral protein processing
  + 5 more...
.calcium-dependent protein binding .extracellular exosome
.late endosome membrane
.endosome membrane
.ESCRT I complex
5 EBI-740322,EBI-10179231 SIRPB1  
  .innate immune response
.cell surface receptor signaling pathway
.signal transduction
.N/A .extracellular exosome
.integral component of plasma membrane
.plasma membrane
6 EBI-740322,EBI-711810 BHLHE40  
  .negative regulation of transcription, DNA-templated
.negative regulation of sequence-specific DNA binding transcription factor activity
.entrainment of circadian clock by photoperiod
  + 4 more...
.E-box binding
.protein heterodimerization activity
.MRF binding
  + 10 more...
.Golgi apparatus
.nucleolus
.nucleoplasm
.nucleus
7 EBI-740322,EBI-719542 DPYSL4  
  .neuron death
.axon guidance
.nervous system development
.hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds .cytosol
8 EBI-740322,EBI-530034 PHF1  
  .positive regulation of histone H3-K27 methylation
.negative regulation of histone H3-K27 methylation
.negative regulation of gene expression, epigenetic
  + 5 more...
.methylated histone binding
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.site of double-strand break
.microtubule organizing center
.cytoplasm
  + 2 more...
9 EBI-740322,EBI-10188645 GCM2  
  .cellular response to organic substance
.parathyroid gland development
.negative regulation of apoptotic process
  + 6 more...
.metal ion binding
.sequence-specific DNA binding
.DNA binding
.nucleus
10 EBI-740322,EBI-1052725 TUSC2  
  .regulation of reactive oxygen species metabolic process
.chemokine (C-C motif) ligand 5 production
.neutrophil mediated killing of gram-negative bacterium
  + 12 more...
.N/A .mitochondrion
11 EBI-740322,EBI-739806 CCNK  
  .positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues
.negative regulation of cell cycle arrest
.cell division
  + 8 more...
.protein kinase binding
.RNA polymerase II carboxy-terminal domain kinase activity
.cyclin-dependent protein serine/threonine kinase activity
.nucleus
.cyclin K-CDK13 complex
.cyclin K-CDK12 complex
12 EBI-740322,EBI-2367123 RHOBTB3  
  .retrograde transport, endosome to Golgi
.metabolic process
.small GTPase mediated signal transduction
.Rab GTPase binding
.ATPase activity
.GTP binding
.ATP binding
.extracellular exosome
.Golgi apparatus
13 EBI-740322,EBI-10191303 VENTX  
  .multicellular organismal development
.regulation of transcription, DNA-templated
.sequence-specific DNA binding .nucleus
14 EBI-740322,EBI-2824328 TBX6  
  .positive regulation of transcription from RNA polymerase II promoter
.somite rostral/caudal axis specification
.signal transduction involved in regulation of gene expression
  + 7 more...
.sequence-specific DNA binding transcription factor activity
.DNA binding
.RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
  + 2 more...
.nucleus
15 EBI-740322,EBI-743414 EFEMP2  
  .extracellular matrix organization .calcium ion binding
.extracellular matrix structural constituent
.extracellular exosome
.vesicle
.basement membrane
.extracellular region
16 EBI-740322,EBI-7178764 IGF2  
  .positive regulation of glycogen (starch) synthase activity
.positive regulation of steroid hormone biosynthetic process
.cellular response to mechanical stimulus
  + 34 more...
.protein serine/threonine kinase activator activity
.receptor activator activity
.growth factor activity
  + 2 more...
.extracellular exosome
.platelet alpha granule lumen
.plasma membrane
  + 2 more...
17 EBI-740322,EBI-7043337 CRYBA1  
  .visual perception
.lens development in camera-type eye
.structural constituent of eye lens .cytoplasm
.nucleus
18 EBI-740322,EBI-2602175 CSN3  
  .transmembrane transport
.protein stabilization
.lactation
.N/A .extracellular space
.extracellular region
19 EBI-740322,EBI-10196507 -  
  .N/A .insulin-like growth factor binding .N/A
20 EBI-740322,EBI-372475 SNRPB  
  .activation of mitophagy in response to mitochondrial depolarization
.ncRNA metabolic process
.mRNA 3'-end processing
  + 9 more...
.histone pre-mRNA DCP binding
.poly(A) RNA binding
.histone pre-mRNA 3'end processing complex
.catalytic step 2 spliceosome
.U2-type prespliceosome
  + 14 more...
21 EBI-740322,EBI-740446 OTX1  
  .diencephalon morphogenesis
.positive regulation of transcription from RNA polymerase II promoter
.inner ear morphogenesis
  + 3 more...
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.nucleus
22 EBI-740322,EBI-2256865 TIE1  
  .plasma membrane fusion
.response to retinoic acid
.negative regulation of cell migration
  + 7 more...
.ATP binding
.transmembrane receptor protein tyrosine kinase activity
.integral component of plasma membrane
23 EBI-740322,EBI-740785 HOXA1  
  .cochlea morphogenesis
.cochlea development
.cellular response to retinoic acid
  + 24 more...
.sequence-specific DNA binding .nucleus
24 EBI-740322,EBI-3905829 CCNG1  
  .cell division
.negative regulation of apoptotic process
.cell growth
  + 6 more...
.N/A .perinuclear region of cytoplasm
.neuronal cell body
.dendrite
.nucleus
25 EBI-740322,EBI-930964 ATXN1  
  .regulation of excitatory postsynaptic membrane potential
.nuclear export
.lung alveolus development
  + 9 more...
.protein self-association
.identical protein binding
.poly(G) binding
  + 4 more...
.intracellular membrane-bounded organelle
.nuclear inclusion body
.nuclear matrix
  + 3 more...
26 EBI-740322,EBI-1383852 PRKAA2  
  .regulation of energy homeostasis
.membrane organization
.fatty acid homeostasis
  + 31 more...
.[acetyl-CoA carboxylase] kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
.metal ion binding
  + 7 more...
.AMP-activated protein kinase complex
.cytosol
.cytoplasm
.nucleoplasm
27 EBI-740322,EBI-10176379 KRTAP12-2  
  .N/A .N/A .keratin filament
28 EBI-740322,EBI-2798728 LMO4  
  .regulation of cell activation
.thymus development
.positive regulation of transcription from RNA polymerase II promoter
  + 8 more...
.zinc ion binding
.transcription factor binding
.sequence-specific DNA binding transcription factor activity
.enhancer sequence-specific DNA binding
.transcription factor complex
29 EBI-740322,EBI-748265 PITX1  
  .cartilage development
.myoblast fate commitment
.embryonic hindlimb morphogenesis
  + 4 more...
.RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.cytoplasm
.nucleolus
.transcription factor complex
.nucleus
30 EBI-740322,EBI-10172814 PRR20C  
  .N/A .N/A .N/A
31 EBI-740322,EBI-10192698 CREB5  
  .adipose tissue development
.positive regulation of transcription, DNA-templated
.fat cell differentiation
.transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.extracellular exosome
.nucleus
32 EBI-740322,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
33 EBI-740322,EBI-10226430 RIPPLY1  
  .bone morphogenesis
.negative regulation of transcription, DNA-templated
.somite rostral/caudal axis specification
  + 4 more...
.N/A .nucleus
34 EBI-740322,EBI-6509505 INCA1  
  .positive regulation of apoptotic signaling pathway
.negative regulation of cyclin-dependent protein serine/threonine kinase activity
.negative regulation of cell proliferation
.cyclin binding
.cyclin-dependent protein serine/threonine kinase inhibitor activity
.cytoplasm
.nucleus
35 EBI-740322,EBI-1181405 PRKAA1  
  .negative regulation of glucose import in response to insulin stimulus
.regulation of energy homeostasis
.response to camptothecin
  + 42 more...
.[acetyl-CoA carboxylase] kinase activity
.tau-protein kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
  + 7 more...
.AMP-activated protein kinase complex
.apical plasma membrane
.cytosol
  + 4 more...
36 EBI-740322,EBI-713355 GPS2  
  .negative regulation of JNK cascade
.negative regulation of GTPase activity
.JNK cascade
  + 4 more...
.GTPase inhibitor activity
.transcription corepressor activity
.transcriptional repressor complex
.nucleoplasm
37 EBI-740322,EBI-77818 ADAM15  
  .negative regulation of receptor binding
.protein kinase C signaling
.cardiac epithelial to mesenchymal transition
  + 11 more...
.SH3 domain binding
.zinc ion binding
.metallopeptidase activity
  + 2 more...
.extracellular exosome
.cell projection
.integral component of membrane
  + 4 more...
38 EBI-740322,EBI-714158 PIN1  
  .negative regulation of cell motility
.negative regulation of ERK1 and ERK2 cascade
.regulation of pathway-restricted SMAD protein phosphorylation
  + 11 more...
.phosphothreonine binding
.phosphoserine binding
.GTPase activating protein binding
  + 2 more...
.midbody
.nuclear speck
.cytoplasm
  + 2 more...
39 EBI-740322,EBI-1058722 CAMK2B  
  .positive regulation of apoptotic signaling pathway
.regulation of cellular response to heat
.positive regulation of synapse maturation
  + 22 more...
.protein homodimerization activity
.ATP binding
.calmodulin-dependent protein kinase activity
.spindle midzone
.sarcoplasmic reticulum membrane
.endocytic vesicle membrane
  + 4 more...
40 EBI-740322,EBI-2847510 GRAP  
  .positive regulation of signal transduction
.cell-cell signaling
.Ras protein signal transduction
.SH3/SH2 adaptor activity .cytosol
.cytoplasm
41 EBI-740322,EBI-2108053 NEDD9  
  .cell division
.actin filament bundle assembly
.regulation of growth
  + 5 more...
.N/A .lamellipodium
.cell cortex
.focal adhesion
  + 5 more...
42 EBI-740322,EBI-10217913 RTP5  
  .N/A .N/A .integral component of membrane
43 EBI-740322,EBI-724310 DAZAP2  
  .N/A .WW domain binding .cytoplasm
.nucleus
44 EBI-740322,EBI-2341787 LONRF1  
  .N/A .zinc ion binding
.ATP-dependent peptidase activity
.N/A
45 EBI-740322,EBI-1048945 KRTAP19-5  
  .N/A .N/A .intermediate filament
46 EBI-740322,EBI-10241353 KRTAP19-7  
  .N/A .N/A .intermediate filament
47 EBI-740322,EBI-749970 SMUG1  
  .depyrimidination
.base-excision repair, AP site formation
.base-excision repair
  + 2 more...
.DNA N-glycosylase activity
.single-strand selective uracil DNA N-glycosylase activity
.uracil DNA N-glycosylase activity
  + 2 more...
.intracellular membrane-bounded organelle
.nucleolus
.nucleoplasm
48 EBI-740322,EBI-750105 C1orf111  
  .N/A .N/A .N/A
49 EBI-740322,EBI-740686 DCAF8  
  .protein ubiquitination .N/A .Cul4-RING E3 ubiquitin ligase complex
.cytoplasm
.nucleus
50 EBI-740322,EBI-10219231 ZNF385C  
  .N/A .zinc ion binding
.nucleic acid binding
.nucleus
51 EBI-740322,EBI-9088829 LGALS9C  
  .N/A .carbohydrate binding .N/A
52 EBI-740322,EBI-6660291 C11orf87  
  .N/A .N/A .integral component of membrane
53 EBI-740322,EBI-946029 C1orf94  
  .N/A .N/A .N/A
54 EBI-740322,EBI-7317823 C22orf39  
  .N/A .N/A .N/A
55 EBI-740322,EBI-2802204 PAPD4  
  .histone mRNA catabolic process
.RNA polyadenylation
.mRNA processing
.hematopoietic progenitor cell differentiation
.metal ion binding
.ATP binding
.polynucleotide adenylyltransferase activity
.nuclear RNA-directed RNA polymerase complex
.cytoplasm
56 EBI-740322,EBI-2880244 DOK6  
  .N/A .N/A .N/A
57 EBI-740322,EBI-10254232 VHLL  
  .cellular response to hypoxia
.protein ubiquitination
.N/A .nucleus
58 EBI-740322,EBI-8635958 SPATA8  
  .N/A .N/A .N/A
59 EBI-740322,EBI-10254872 NAPRT  
  .small molecule metabolic process
.NAD metabolic process
.nicotinate nucleotide salvage
  + 5 more...
.ligase activity
.nicotinate phosphoribosyltransferase activity
.nicotinate-nucleotide diphosphorylase (carboxylating) activity
.extracellular exosome
.cytosol
.Golgi apparatus
  + 3 more...
60 EBI-740322,EBI-7844656 TTLL10  
  .cellular protein modification process .N/A .N/A
61 EBI-740322,EBI-4397613 KCTD9  
  .protein homooligomerization .N/A .N/A
62 EBI-740322,EBI-2834978 DOK3  
  .Ras protein signal transduction .N/A .plasma membrane
.cytoplasm
63 EBI-740322,EBI-1389308 POGZ  
  .kinetochore assembly
.cell division
.mitotic sister chromatid cohesion
.metal ion binding
.DNA binding
.cytoplasm
.nucleoplasm
.nucleus
.nuclear chromatin
64 EBI-740322,EBI-740376 DTX2  
  .protein ubiquitination
.Notch signaling pathway
.ligase activity
.zinc ion binding
.nuclear membrane
.cytoplasm
.nucleoplasm
65 EBI-740322,EBI-2683289 SBF2  
  .protein tetramerization
.positive regulation of GTPase activity
.myelination
.phosphatidylinositol binding
.phosphatase regulator activity
.Rab guanyl-nucleotide exchange factor activity
.membrane
.vacuolar membrane
66 EBI-740322,EBI-10261141 KRTAP8-1  
  .N/A .N/A .intermediate filament
67 EBI-740322,EBI-748515 GLYCTK  
  .protein phosphorylation .glycerate kinase activity
.ATP binding
.mitochondrion
.cytoplasm
68 EBI-740322,EBI-2872544 LRRC75A-AS1  
  .N/A .N/A .mitochondrion
69 EBI-740322,EBI-10267998 LINC00482  
  .N/A .N/A .N/A
70 EBI-740322,EBI-744695 BANP  
  .negative regulation of protein catabolic process
.protein localization to nucleus
.chromatin modification
  + 4 more...
.DNA binding .nucleoplasm
71 EBI-740322,EBI-998198 BOLL  
  .positive regulation of translational initiation
.cell differentiation
.spermatogenesis
  + 2 more...
.translation activator activity
.RNA binding
.nucleotide binding
.cytoplasm
72 EBI-740322,EBI-10269322 SMRP1  
  .cellular protein complex assembly
.cell differentiation
.spermatogenesis
.N/A .perinuclear region of cytoplasm
.nucleus
.manchette
73 EBI-740322,EBI-10244131 FBF1  
  .establishment of epithelial cell polarity
.apical junction assembly
.cilium assembly
.organelle organization
.N/A .ciliary transition fiber
.cell junction
.cytosol
  + 3 more...
74 EBI-740322,EBI-535849 HNRNPLL  
  .positive regulation of RNA splicing
.mRNA processing
.poly(A) RNA binding
.mRNA binding
.nucleotide binding
.ribonucleoprotein complex
.membrane
.nucleus
75 EBI-740322,EBI-7957930 FAM168A  
  .N/A .N/A .N/A
76 EBI-740322,EBI-357061 TFG  
  .positive regulation of I-kappaB kinase/NF-kappaB signaling
.signal transduction
.signal transducer activity .extracellular exosome
.cytoplasm
77 EBI-740322,EBI-739990 POM121  
  .regulation of cellular response to heat
.transmembrane transport
.mRNA transport
  + 17 more...
.N/A .nuclear membrane
.endoplasmic reticulum membrane
.nuclear pore
.nuclear envelope
78 EBI-740322,EBI-741158 WDYHV1  
  .cellular protein modification process .protein-N-terminal glutamine amidohydrolase activity .cytosol
.nucleus
79 EBI-740322,EBI-742550 ZC3H10  
  .N/A .metal ion binding
.poly(A) RNA binding
.N/A
80 EBI-740322,EBI-9478492 WDR90  
  .N/A .N/A .N/A
81 EBI-740322,EBI-743976 TEX37  
  .N/A .N/A .nucleus
82 EBI-740322,EBI-948288 ZNF488  
  .positive regulation of oligodendrocyte differentiation
.negative regulation of transcription, DNA-templated
.oligodendrocyte development
  + 2 more...
.metal ion binding
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
83 EBI-740322,EBI-3916363 RDH12  
  .photoreceptor cell maintenance
.retinol metabolic process
.phototransduction, visible light
  + 2 more...
.retinol dehydrogenase activity .photoreceptor inner segment membrane
.intracellular
84 EBI-740322,EBI-945792 QKI  
  .3'-UTR-mediated mRNA destabilization
.mRNA transport
.long-chain fatty acid biosynthetic process
  + 8 more...
.poly(A) RNA binding
.mRNA binding
.cytoplasm
.nucleus
85 EBI-740322,EBI-740355 STRBP  
  .mechanosensory behavior
.spermatid development
.multicellular organismal development
.poly(A) RNA binding
.single-stranded RNA binding
.double-stranded RNA binding
.DNA binding
.microtubule cytoskeleton
.cytoplasm
.nucleus
86 EBI-740322,EBI-2510250 CRBN  
  .positive regulation of protein homodimerization activity
.proteasome-mediated ubiquitin-dependent protein catabolic process
.negative regulation of ion transmembrane transport
  + 2 more...
.metal ion binding
.ATP-dependent peptidase activity
.Cul4A-RING E3 ubiquitin ligase complex
.membrane
.cytoplasm
  + 2 more...
87 EBI-740322,EBI-10294579 KIR2DL4  
  .regulation of immune response
.signal transduction
.cellular defense response
.transmembrane signaling receptor activity .membrane
.integral component of plasma membrane
.plasma membrane
88 EBI-740322,EBI-3956892 FOXC2  
  .negative regulation of apoptotic process involved in outflow tract morphogenesis
.positive regulation of cell migration involved in sprouting angiogenesis
.glomerular mesangial cell development
  + 34 more...
.transcription regulatory region DNA binding
.sequence-specific DNA binding
.chromatin DNA binding
  + 3 more...
.nucleus
89 EBI-740322,EBI-372094 RHOXF2  
  .regulation of transcription, DNA-templated .sequence-specific DNA binding .nucleus
90 EBI-740322,EBI-747324 DCTN5  
  .antigen processing and presentation of exogenous peptide antigen via MHC class II .N/A .cytosol
.centrosome
.condensed chromosome kinetochore
91 EBI-740322,EBI-6257312 RUSC1  
  .positive regulation of signal transduction
.protein polyubiquitination
.SH3/SH2 adaptor activity
.actin binding
.postsynaptic membrane
.cytoplasmic vesicle
.cell junction
  + 8 more...
92 EBI-740322,EBI-744935 C20orf195  
  .N/A .N/A .extracellular exosome
93 EBI-740322,EBI-748297 BBS2  
  .protein localization to ciliary membrane
.regulation of cilium beat frequency involved in ciliary motility
.cilium morphogenesis
  + 23 more...
.RNA polymerase II repressing transcription factor binding .ciliary membrane
.ciliary basal body
.BBSome
  + 3 more...
94 EBI-740322,EBI-983719 FOXP3  
  .negative regulation of T-helper 17 cell differentiation
.T cell receptor signaling pathway
.negative regulation of immune response
  + 48 more...
.NFAT protein binding
.NF-kappaB binding
.metal ion binding
  + 9 more...
.protein complex
.cytoplasm
.nucleus
95 EBI-740322,EBI-10303636 TINAGL1  
  .endosomal transport
.cell adhesion
.immune response
.polysaccharide binding
.cysteine-type peptidase activity
.extracellular matrix structural constituent
.scavenger receptor activity
.extracellular exosome
.cytoplasm
.extracellular space
.extracellular region
96 EBI-740322,EBI-74615 TOLLIP  
  .leukocyte activation
.innate immune response
.protein localization to endosome
  + 8 more...
.Toll-like receptor binding
.kinase binding
.signal transducer activity
.extracellular exosome
.perinuclear region of cytoplasm
.interleukin-1 receptor complex
  + 4 more...
97 EBI-740322,EBI-2510146 TOR1AIP2  
  .N/A .N/A .N/A
98 EBI-740322,EBI-741626 FAM124B  
  .N/A .N/A .N/A
99 EBI-740322,EBI-746712 MYOZ2  
  .N/A .telethonin binding
.protein phosphatase 2B binding
.Z disc
.sarcomere
.actin cytoskeleton
100 EBI-740322,EBI-751092 HEYL  
  .negative regulation of androgen receptor activity
.proximal tubule development
.cellular response to BMP stimulus
  + 16 more...
.AF-1 domain binding
.protein heterodimerization activity
.microsatellite binding
  + 8 more...
.cytoplasm
.nucleoplasm
.nucleus
101 EBI-740322,EBI-9679045 DMRT3  
  .male sex differentiation
.regulation of odontogenesis of dentin-containing tooth
.ventral spinal cord interneuron specification
  + 4 more...
.protein heterodimerization activity
.metal ion binding
.protein homodimerization activity
  + 2 more...
.nucleus
102 EBI-740322,EBI-2881520 INIP  
  .response to ionizing radiation
.cellular response to DNA damage stimulus
.DNA repair
.N/A .SOSS complex
.nucleoplasm
.nucleus
103 EBI-740322,EBI-9089805 SEMA4G  
  .cell differentiation
.nervous system development
.receptor activity .integral component of membrane
.plasma membrane
104 EBI-740322,EBI-945906 RBFOX1  
  .neuromuscular process controlling balance
.RNA transport
.regulation of RNA splicing
  + 2 more...
.protein C-terminus binding
.RNA binding
.nucleotide binding
.trans-Golgi network
.cytoplasm
.nucleus
105 EBI-740322,EBI-5666657 GPATCH2L  
  .N/A .N/A .N/A
106 EBI-740322,EBI-357318 PIH1D1  
  .epithelial cell differentiation
.box C/D snoRNP assembly
.N/A .pre-snoRNP complex
107 EBI-740322,EBI-745520 ZNF581  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
108 EBI-740322,EBI-750630 HEY2  
  .regulation of vasculogenesis
.negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
.negative regulation of cardiac vascular smooth muscle cell differentiation
  + 47 more...
.sequence-specific DNA binding
.histone deacetylase binding
.microsatellite binding
  + 5 more...
.transcriptional repressor complex
.cytoplasm
.nucleoplasm
.nucleus
109 EBI-740322,EBI-747509 IP6K2  
  .type I interferon signaling pathway
.phosphatidylinositol phosphorylation
.small molecule metabolic process
  + 5 more...
.inositol hexakisphosphate 3-kinase activity
.inositol hexakisphosphate 1-kinase activity
.inositol-1,4,5-trisphosphate 3-kinase activity
  + 2 more...
.intermediate filament cytoskeleton
.nucleoplasm
.nucleus
110 EBI-740322,EBI-396137 CDC23  
  .protein K11-linked ubiquitination
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
.positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
  + 11 more...
.ubiquitin-protein transferase activity .cytosol
.anaphase-promoting complex
.nucleoplasm
.intracellular
111 EBI-740322,EBI-717201 SPG7  
  .anterograde axon cargo transport
.nervous system development
.mitochondrion organization
.proteolysis
.unfolded protein binding
.zinc ion binding
.peptidase activity
  + 2 more...
.mitochondrial membrane
.integral component of membrane
.mitochondrion
112 EBI-740322,EBI-10326419 R3HDM2  
  .N/A .poly(A) RNA binding .nucleus
113 EBI-740322,EBI-10039207 LINC00588  
  .N/A .N/A .N/A
114 EBI-740322,EBI-8583355 AMMECR1  
  .N/A .N/A .N/A
115 EBI-740322,EBI-716006 MAGED1  
  .positive regulation of apoptotic signaling pathway
.extrinsic apoptotic signaling pathway in absence of ligand
.extrinsic apoptotic signaling pathway
  + 15 more...
.transcription coactivator activity .protein complex
.plasma membrane
.cytoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
bladder33
bone13
brain14
cervix20
connective tissue33
embryonic tissue98
eye110
heart78
intestine133
kidney80
liver29
lung44
lymph22
mammary gland85
mouth15
muscle28
nerve321
ovary197
pancreas89
placenta98
prostate84
skin28
stomach167
testis55
thymus50
thyroid85
trachea38
uterus90
vascular19
Health State
TissuesTPM*
normal59
breast (mammary gland) tumor32
chondrosarcoma48
colorectal tumor186
gastrointestinal tumor92
germ cell tumor49
glioma18
head and neck tumor29
kidney tumor130
liver tumor62
lymphoma13
non-neoplasia20
ovarian tumor223
pancreatic tumor76
prostate cancer9
skin tumor23
soft tissue/muscle tissue tumor7
uterine tumor77
Developmental Stage
TissuesTPM*
adult82
embryoid body128
blastocyst81
fetus23
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue141.6
adrenal gland87.5
appendix69.7
bone marrow1.5
cerebral cortex7
colon77.8
duodenum38.6
esophagus230.1
gallbladder235.3
heart muscle275.5
kidney85.4
liver32
lung117.5
lymph node49.2
ovary228.9
pancreas48.8
placenta142
prostate136.1
salivary gland63.5
skin15.4
small intestine41.2
spleen44.8
stomach39.2
testis55.8
thyroid gland208
urinary bladder348.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*601558, gene) Rna-binding protein gene with multiple splicing; RBPMSOMIM


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