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> Protein (NX_Q969F0)
Protein (NX_Q969F0)
Protein
Gene SymbolFATE1 to neXtProt (NX_Q969F0)
DescriptionFetal and adult testis-expressed transcript protein
ChromosomeX
LocationXq28 (150884507 ~ 150891666) to Ensembl
Sequene Features : Isoforms 1, Variants 42, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .integral component of membrane
.endoplasmic reticulum
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 42 0
2014-09-19protein level
1 30 0
2014-05-27transcript level
1 30 0
2014-02-25transcript level
1 29 0
2013-12-09transcript level
1 25 0
2013-11-01transcript level
1 25 0
2013-09-12transcript level
1 25 0
2013-08-17transcript level
1 25 0
2013-07-15transcript level
1 18 0
2013-06-11transcript level
1 18 0
2013-02-12transcript level
1 9 0
2012-12-20transcript level
1 8 0
2012-10-30transcript level
1 9 0
2012-10-07transcript level
1 9 0
2012-08-24transcript level
1 8 0
2012-07-28transcript level
1 8 0
2012-06-08transcript level
1 7 0
2012-05-07transcript level
1 7 0
2012-04-10transcript level
1 7 0
2012-01-13transcript level
1 3 0
2011-12-20transcript level
1 3 0
2011-11-11transcript level
1 3 0
2011-08-23transcript level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q969F0-1
10 0 0 20698.356
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-743099,EBI-6269521 SYNGR1  
  .regulation of short-term neuronal synaptic plasticity
.regulation of long-term neuronal synaptic plasticity
.protein targeting
.N/A .melanosome
.neuromuscular junction
.synaptic vesicle membrane
  + 2 more...
2 EBI-743099,EBI-849893 BNIP3L  
  .mitochondrial outer membrane permeabilization
.defense response to virus
.negative regulation of apoptotic process
  + 3 more...
.protein heterodimerization activity
.protein homodimerization activity
.identical protein binding
.lamin binding
.intrinsic component of membrane
.integral component of membrane
.endoplasmic reticulum
  + 3 more...
3 EBI-743099,EBI-10186753 LY75  
  .immune response
.inflammatory response
.endocytosis
.carbohydrate binding
.receptor activity
.extracellular exosome
.integral component of plasma membrane
4 EBI-743099,EBI-7797864 CD79A  
  .B cell receptor signaling pathway
.B cell activation
.B cell proliferation
.B cell differentiation
.transmembrane signaling receptor activity .membrane raft
.B cell receptor complex
.integral component of membrane
  + 3 more...
5 EBI-743099,EBI-1763264 CSF2RA  
  .response to ethanol .cytokine receptor activity
.receptor activity
.integral component of plasma membrane
.plasma membrane
.extracellular region
6 EBI-743099,EBI-4289564 SLC7A1  
  .L-lysine transmembrane transport
.L-ornithine transmembrane transport
.L-arginine import across plasma membrane
  + 4 more...
.antiporter activity
.L-lysine transmembrane transporter activity
.arginine transmembrane transporter activity
.L-ornithine transmembrane transporter activity
.membrane
.integral component of plasma membrane
.plasma membrane
7 EBI-743099,EBI-8650934 TM4SF4  
  .tissue regeneration .N/A .integral component of membrane
8 EBI-743099,EBI-489887 EMD  
  .cellular response to growth factor stimulus
.regulation of canonical Wnt signaling pathway
.negative regulation of fibroblast proliferation
  + 8 more...
.beta-tubulin binding
.actin binding
.nuclear membrane
.integral component of membrane
.membrane
  + 5 more...
9 EBI-743099,EBI-752094 BNIP2  
  .positive regulation of muscle cell differentiation
.positive regulation of GTPase activity
.negative regulation of apoptotic process
  + 2 more...
.identical protein binding
.calcium ion binding
.GTPase activator activity
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.cytosol
  + 2 more...
10 EBI-743099,EBI-749464 BNIP3  
  .intrinsic apoptotic signaling pathway in response to hypoxia
.toxin transport
.mitochondrial outer membrane permeabilization
  + 28 more...
.GTPase binding
.protein heterodimerization activity
.protein homodimerization activity
.identical protein binding
.mitochondrial membrane
.integral component of mitochondrial outer membrane
.dendrite
  + 7 more...
11 EBI-743099,EBI-700794 BIK  
  .positive regulation of release of cytochrome c from mitochondria
.positive regulation of protein homooligomerization
.apoptotic mitochondrial changes
  + 3 more...
.N/A .mitochondrial membrane
.integral component of membrane
.endomembrane system
12 EBI-743099,EBI-742673 SEC23B  
  .vesicle-mediated transport
.ER to Golgi vesicle-mediated transport
.intracellular protein transport
.zinc ion binding .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.endoplasmic reticulum-Golgi intermediate compartment membrane
  + 5 more...
13 EBI-743099,EBI-10244848 SNAP47  
  .long-term synaptic potentiation
.synaptic vesicle fusion to presynaptic membrane
.synaptic vesicle priming
.syntaxin binding
.SNAP receptor activity
.perinuclear region of cytoplasm
.neuronal cell body
.SNARE complex
  + 3 more...
14 EBI-743099,EBI-6873045 CCDC70  
  .N/A .N/A .plasma membrane
.extracellular region
15 EBI-743099,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
16 EBI-743099,EBI-10264528 NRSN1  
  .nervous system development .N/A .neuronal cell body
.neuron projection
.growth cone
  + 3 more...
17 EBI-743099,EBI-7131783 SYNE4  
  .establishment of epithelial cell apical/basal polarity .N/A .LINC complex
.integral component of nuclear outer membrane
18 EBI-743099,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
19 EBI-743099,EBI-10273251 SYNPR  
  .N/A .transporter activity .neuron projection
.synaptic vesicle membrane
.integral component of synaptic vesicle membrane
.cell junction
20 EBI-743099,EBI-8648738 BTN2A2  
  .negative regulation of cytokine secretion
.negative regulation of activated T cell proliferation
.negative regulation of cellular metabolic process
.N/A .extracellular exosome
.integral component of membrane
21 EBI-743099,EBI-8637292 NRG4  
  .organ development
.phosphatidylinositol-mediated signaling
.neurotrophin TRK receptor signaling pathway
  + 5 more...
.receptor binding .integral component of membrane
.plasma membrane
.extracellular space
.extracellular region
22 EBI-743099,EBI-707714 BCL2L2  
  .negative regulation of intrinsic apoptotic signaling pathway
.extrinsic apoptotic signaling pathway in absence of ligand
.Sertoli cell proliferation
  + 3 more...
.protein heterodimerization activity
.protein homodimerization activity
.extracellular exosome
.cytosol
.mitochondrial outer membrane
23 EBI-743099,EBI-10280401 MR1  
  .defense response to Gram-negative bacterium
.innate immune response
.interleukin-17 production
  + 7 more...
.peptide antigen binding
.MHC class I receptor activity
.antigen binding
.MHC class I protein complex
.integral component of membrane
.plasma membrane
  + 3 more...
24 EBI-743099,EBI-8652744 SEC22A  
  .vesicle fusion with Golgi apparatus
.protein transport
.ER to Golgi vesicle-mediated transport
.SNAP receptor activity
.transporter activity
.SNARE binding
.SNARE complex
.integral component of membrane
.endoplasmic reticulum membrane
25 EBI-743099,EBI-10292091 TMEM74  
  .autophagy .N/A .cytoplasmic vesicle
.integral component of membrane
.lysosomal membrane
.autophagic vacuole membrane
26 EBI-743099,EBI-10297029 SEC22C  
  .vesicle fusion with Golgi apparatus
.protein transport
.ER to Golgi vesicle-mediated transport
.SNAP receptor activity
.SNARE binding
.SNARE complex
.integral component of membrane
.endoplasmic reticulum membrane
.endoplasmic reticulum
27 EBI-743099,EBI-751253 YIPF4  
  .N/A .N/A .intracellular membrane-bounded organelle
.integral component of membrane
.plasma membrane
  + 2 more...
28 EBI-743099,EBI-749162 INPP5K  
  .positive regulation of renal water transport
.negative regulation of glycogen (starch) synthase activity
.ruffle assembly
  + 35 more...
.inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
.inositol-1,4,5-trisphosphate 5-phosphatase activity
.inositol trisphosphate phosphatase activity
  + 7 more...
.perinuclear region of cytoplasm
.neuron projection
.ruffle membrane
  + 8 more...
29 EBI-743099,EBI-747324 DCTN5  
  .antigen processing and presentation of exogenous peptide antigen via MHC class II .N/A .cytosol
.centrosome
.condensed chromosome kinetochore
30 EBI-743099,EBI-9978441 SLC38A1  
  .organic acid transmembrane transport
.transmembrane transport
.neutral amino acid transport
  + 5 more...
.neutral amino acid transmembrane transporter activity
.sodium:amino acid symporter activity
.extracellular exosome
.integral component of membrane
.integral component of plasma membrane
.plasma membrane
31 EBI-743099,EBI-726331 SYNDIG1  
  .synaptic vesicle clustering
.positive regulation of synapse assembly
.response to biotic stimulus
.intracellular protein transport
.protein homodimerization activity
.glutamate receptor binding
.excitatory synapse
.postsynaptic membrane
.cell body
  + 6 more...
32 EBI-743099,EBI-6268651 TIMMDC1  
  .N/A .N/A .mitochondrial membrane
.integral component of membrane
.mitochondrion
.nucleoplasm
33 EBI-743099,EBI-1052363 RPRM  
  .regulation of mitotic cell cycle
.cell cycle arrest
.N/A .integral component of membrane
.cytoplasm
34 EBI-743099,EBI-1246182 NDUFB11  
  .small molecule metabolic process
.cellular metabolic process
.respiratory electron transport chain
.N/A .integral component of membrane
.mitochondrial respiratory chain complex I
.mitochondrial inner membrane
.mitochondrion
35 EBI-743099,EBI-2341610 MARCH5  
  .negative regulation of cell aging
.positive regulation of mitochondrial fission
.regulation of mitochondrial fission
  + 3 more...
.GTPase binding
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.integral component of membrane
.membrane
.endoplasmic reticulum membrane
  + 2 more...
36 EBI-743099,EBI-10317612 MARCH2  
  .protein ubiquitination
.endocytosis
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasmic vesicle
.integral component of membrane
.endosome membrane
  + 3 more...
37 EBI-743099,EBI-2805360 LNPEP  
  .membrane organization
.SMAD protein signal transduction
.antigen processing and presentation of exogenous peptide antigen via MHC class I
  + 7 more...
.zinc ion binding
.metallopeptidase activity
.aminopeptidase activity
.perinuclear region of cytoplasm
.early endosome lumen
.cytoplasmic vesicle membrane
  + 7 more...
38 EBI-743099,EBI-10323864 KCNS2  
  .potassium ion transmembrane transport
.protein homooligomerization
.synaptic transmission
.delayed rectifier potassium channel activity .integral component of membrane
.voltage-gated potassium channel complex
.plasma membrane
39 EBI-743099,EBI-765817 TRAF3IP3  
  .N/A .N/A .integral component of membrane
40 EBI-743099,EBI-714599 PIN4  
  .rRNA processing .poly(A) RNA binding
.peptidyl-prolyl cis-trans isomerase activity
.double-stranded DNA binding
  + 2 more...
.extracellular exosome
.preribosome
.spindle
  + 4 more...
41 EBI-743099,EBI-2511991 USP20  
  .protein K48-linked deubiquitination
.protein K63-linked deubiquitination
.regulation of proteasomal protein catabolic process
  + 4 more...
.zinc ion binding
.ubiquitin-specific protease activity
.cysteine-type endopeptidase activity
.G-protein coupled receptor binding
.perinuclear region of cytoplasm
.centrosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
brain11
placenta7
testis149
Health State
TissuesTPM*
normal11
adrenal tumor158
germ cell tumor3
Developmental Stage
TissuesTPM*
adult10
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis178.2
Tissues
TissuesExpression level
colonLow
duodenumMedium
rectumLow
small intestineMedium
testisMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300450, gene) Fetal and adult testis-expressed gene 1; FATE1OMIM


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