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> Protein (NX_Q969G2)
Protein (NX_Q969G2)
Protein
Gene SymbolLHX4 to neXtProt (NX_Q969G2)
DescriptionLIM/homeobox protein Lhx4
Chromosome1
Location1q25.2 (180199421 ~ 180249380) to Ensembl
Sequene Features : Isoforms 1, Variants 56, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of apoptotic process
.medial motor column neuron differentiation
.organ morphogenesis
  + 4 more...
.sequence-specific DNA binding
.zinc ion binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 56 0
2014-09-19protein level
1 39 0
2014-05-27protein level
1 39 0
2014-02-25protein level
1 38 0
2013-12-09protein level
1 32 0
2013-11-01protein level
1 32 0
2013-09-12protein level
1 32 0
2013-08-17protein level
1 32 0
2013-07-15protein level
1 18 0
2013-06-11protein level
1 18 0
2013-02-12protein level
1 11 0
2012-12-20protein level
1 11 0
2012-10-30protein level
1 12 0
2012-10-07protein level
1 12 0
2012-08-24protein level
1 11 0
2012-07-28protein level
1 11 0
2012-06-08protein level
1 12 0
2012-05-07protein level
1 12 0
2012-04-10protein level
1 12 0
2012-01-13protein level
1 7 0
2011-12-20protein level
1 7 0
2011-11-11protein level
1 7 0
2011-08-23protein level
1 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q969G2-1
13 0 2 43095.8002
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2865388,EBI-6983382 SH2D1A  
  .positive regulation of natural killer cell mediated cytotoxicity
.positive regulation of signal transduction
.cell-cell signaling
  + 2 more...
.SH3/SH2 adaptor activity .cytoplasm
2 EBI-2865388,EBI-743272 USP2  
  .regulation of proteasomal protein catabolic process
.protein stabilization
.positive regulation of skeletal muscle tissue development
  + 11 more...
.metal ion binding
.ubiquitin protein ligase binding
.cyclin binding
  + 2 more...
.perinuclear region of cytoplasm
.cell cortex
.centrosome
  + 2 more...
3 EBI-2865388,EBI-2341787 LONRF1  
  .N/A .zinc ion binding
.ATP-dependent peptidase activity
.N/A
4 EBI-2865388,EBI-10252800 FDX1L  
  .oxidation-reduction process
.small molecule metabolic process
.sterol metabolic process
  + 3 more...
.2 iron, 2 sulfur cluster binding
.metal ion binding
.electron carrier activity
.mitochondrial matrix
5 EBI-2865388,EBI-9675976 SNRNP25  
  .RNA splicing
.mRNA processing
.N/A .intercellular bridge
.cytoplasm
.U12-type spliceosomal complex
  + 2 more...
6 EBI-2865388,EBI-374840 ORC6  
  .DNA-dependent DNA replication
.DNA replication
.mitotic cell cycle
.G1/S transition of mitotic cell cycle
.DNA binding .membrane
.plasma membrane
.nuclear origin of replication recognition complex
  + 3 more...
7 EBI-2865388,EBI-2321769 CHCHD2  
  .regulation of cellular response to hypoxia
.positive regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.sequence-specific DNA binding
.transcription factor binding
.mitochondrion
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
muscle37
uterus8
Health State
TissuesTPM*
normal1
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
placenta1.1
testis2.2
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(#262700, phenotype) Pituitary hormone deficiency, combined, 4; CPHD4OMIM
2(*602146, gene) Lim homeobox gene 4; LHX4OMIM


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