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> Protein (NX_Q969L2)
Protein (NX_Q969L2)
Protein
Gene SymbolMAL2 to neXtProt (NX_Q969L2)
DescriptionProtein MAL2
Chromosome8
Location8q24.12 (120177273 ~ 120257913) to Ensembl
Sequene Features : Isoforms 1, Variants 1, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .extracellular exosome
.perinuclear region of cytoplasm
.membrane raft
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 1 1
2014-09-19protein level
1 1 1
2014-05-27protein level
1 1 1
2014-02-25protein level
1 1 1
2013-12-09protein level
1 1 1
2013-11-01protein level
1 1 1
2013-09-12protein level
1 1 1
2013-08-17protein level
1 1 1
2013-07-15protein level
1 1 1
2013-06-11protein level
1 1 1
2013-02-12protein level
1 1 1
2012-12-20protein level
1 1 1
2012-10-30protein level
1 1 1
2012-10-07protein level
1 1 1
2012-08-24protein level
1 1 1
2012-07-28protein level
1 1 1
2012-06-08protein level
1 1 1
2012-05-07protein level
1 1 1
2012-04-10protein level
1 1 1
2012-01-13protein level
1 1 1
2011-12-20protein level
1 1 1
2011-11-11protein level
1 1 1
2011-08-23protein level
1 1 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q969L2-1
3 0 0 19112.6384
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-944295,EBI-742898 PTPN9  
  .peptidyl-tyrosine dephosphorylation
.protein dephosphorylation
.non-membrane spanning protein tyrosine phosphatase activity
.protein tyrosine phosphatase activity
.cytoplasm
2 EBI-944295,EBI-638194 ARFIP2  
  .regulation of Arp2/3 complex-mediated actin nucleation
.ruffle organization
.actin cytoskeleton organization
  + 3 more...
.phosphatidylinositol-4-phosphate binding
.Rac GTPase binding
.GTP-dependent protein binding
.GTP binding
.trans-Golgi network membrane
.cell cortex
.plasma membrane
  + 2 more...
3 EBI-944295,EBI-9304251 GAD2  
  .response to drug
.neurotransmitter biosynthetic process
.neurotransmitter secretion
  + 2 more...
.pyridoxal phosphate binding
.glutamate binding
.glutamate decarboxylase activity
.clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
.perinuclear region of cytoplasm
.presynaptic membrane
  + 7 more...
4 EBI-944295,EBI-10244969 VARS2  
  .gene expression
.valyl-tRNA aminoacylation
.tRNA aminoacylation for protein translation
.ATP binding
.valine-tRNA ligase activity
.aminoacyl-tRNA editing activity
.mitochondrion
5 EBI-944295,EBI-702328 TBRG4  
  .cellular respiration
.positive regulation of cell proliferation
.cell cycle arrest
.poly(A) RNA binding
.protein kinase activity
.mitochondrion
6 EBI-944295,EBI-748121 RAB37  
  .protein localization to plasma membrane
.Rab protein signal transduction
.regulation of exocytosis
  + 4 more...
.GTP binding
.GTPase activity
.secretory granule membrane
.plasma membrane
.endoplasmic reticulum-Golgi intermediate compartment
.endosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites225
bladder468
bone marrow102
brain32
cervix103
connective tissue13
embryonic tissue37
esophagus148
eye43
heart44
intestine444
kidney56
larynx85
liver97
lung77
lymph22
lymph node122
mammary gland105
mouth75
ovary147
pancreas74
parathyroid388
pharynx98
pituitary gland60
placenta81
prostate174
skin9
stomach324
testis18
thyroid214
trachea19
uterus77
vascular38
Health State
TissuesTPM*
normal48
bladder carcinoma454
breast (mammary gland) tumor161
cervical tumor115
chondrosarcoma24
colorectal tumor728
esophageal tumor173
gastrointestinal tumor320
germ cell tumor79
head and neck tumor127
leukemia52
liver tumor187
lung tumor38
lymphoma13
non-neoplasia93
ovarian tumor170
pancreatic tumor114
prostate cancer260
uterine tumor155
Developmental Stage
TissuesTPM*
adult121
embryoid body57
fetus55
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue11.8
adrenal gland2
appendix11.7
cerebral cortex34.9
colon96
duodenum60.7
esophagus234.9
gallbladder36.7
heart muscle1.7
kidney74.3
liver22.4
lung81.8
lymph node1.2
pancreas17.9
placenta12.6
prostate27.3
salivary gland23
skin122.4
small intestine50.3
stomach118
testis13.2
thyroid gland142
urinary bladder63.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609684, gene) Mal proteolipid protein 2; MAL2OMIM


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