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> Protein (NX_Q969Q6)
Protein (NX_Q969Q6)
Protein
Gene SymbolPPP2R3C to neXtProt (NX_Q969Q6)
DescriptionSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
Chromosome14
Location14q13.2 (35554673 ~ 35591723) to Ensembl
Sequene Features : Isoforms 2, Variants 45, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of mitochondrial depolarization
.spleen development
.positive regulation of B cell differentiation
  + 6 more...
.metal ion binding .spindle
.centrosome
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 45 1
2014-09-19protein level
2 36 1
2014-05-27protein level
2 36 1
2014-02-25protein level
2 36 1
2013-12-09protein level
2 30 1
2013-11-01protein level
2 30 0
2013-09-12protein level
2 30 0
2013-08-17protein level
2 30 0
2013-07-15protein level
2 19 0
2013-06-11protein level
2 19 0
2013-02-12protein level
2 9 0
2012-12-20protein level
2 9 0
2012-10-30protein level
2 11 0
2012-10-07protein level
2 11 0
2012-08-24protein level
2 7 0
2012-07-28protein level
2 7 0
2012-06-08protein level
2 10 0
2012-05-07protein level
2 10 0
2012-04-10protein level
2 10 0
2012-01-13protein level
2 5 0
2011-12-20protein level
2 5 0
2011-11-11protein level
2 5 0
2011-08-23protein level
2 5 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q969Q6-1
5 19 0 53281.7609
NX_Q969Q6-2
1 19 0 39780.8594
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2561661,EBI-1055079 POLR1C  
  .negative regulation of gene expression, epigenetic
.innate immune response
.regulation of gene expression, epigenetic
  + 9 more...
.DNA-directed RNA polymerase activity
.DNA binding
.cytosol
.DNA-directed RNA polymerase I complex
.DNA-directed RNA polymerase III complex
.nucleoplasm
2 EBI-2561661,EBI-740467 RTN3  
  .endoplasmic reticulum tubular network organization
.vesicle-mediated transport
.viral process
.apoptotic process
.N/A .extracellular exosome
.integral component of membrane
.endoplasmic reticulum membrane
  + 3 more...
3 EBI-2561661,EBI-2548702 CMTM5  
  .negative regulation of myoblast differentiation
.chemotaxis
.N/A .integral component of membrane
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites50
bladder33
blood32
bone marrow61
brain54
cervix41
connective tissue194
ear62
embryonic tissue56
esophagus148
eye57
heart67
intestine34
kidney47
liver24
lung47
lymph22
lymph node77
mammary gland13
muscle28
nerve128
ovary9
pancreas51
pharynx171
pituitary gland60
placenta49
prostate47
salivary gland49
skin52
spleen18
stomach31
testis156
thymus25
tonsil58
trachea19
uterus51
vascular58
Health State
TissuesTPM*
normal59
bladder carcinoma56
breast (mammary gland) tumor21
cervical tumor57
chondrosarcoma24
colorectal tumor17
esophageal tumor173
gastrointestinal tumor33
germ cell tumor49
glioma18
kidney tumor29
leukemia42
liver tumor20
lung tumor29
lymphoma69
non-neoplasia10
ovarian tumor26
primitive neuroectodermal tumor of the CNS228
prostate cancer28
retinoblastoma86
skin tumor15
soft tissue/muscle tissue tumor247
uterine tumor55
Developmental Stage
TissuesTPM*
adult49
embryoid body28
blastocyst16
fetus46
infant340
juvenile125
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.3
adrenal gland17.2
appendix26.8
bone marrow27.6
cerebral cortex22
colon18.5
duodenum21.7
esophagus14.2
gallbladder21.3
heart muscle18.1
kidney12.7
liver7.6
lung16.4
lymph node30.2
ovary18.3
pancreas4.5
placenta16
prostate17.6
salivary gland11.7
skin6
small intestine21.8
spleen20.8
stomach15.8
testis56.6
thyroid gland13.7
urinary bladder27.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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