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> Protein (NX_Q969U7)
Protein (NX_Q969U7)
Protein
Gene SymbolPSMG2 to neXtProt (NX_Q969U7)
DescriptionProteasome assembly chaperone 2
Chromosome18
Location18p11.21 (12658737 ~ 12725739) to Ensembl
Sequene Features : Isoforms 2, Variants 28, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.proteasome assembly
.negative regulation of apoptotic process
.mitotic spindle assembly checkpoint
.N/A .nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 28 5
2014-09-19protein level
2 24 5
2014-05-27protein level
1 24 5
2014-02-25protein level
1 24 5
2013-12-09protein level
1 19 5
2013-11-01protein level
1 19 3
2013-09-12protein level
1 19 3
2013-08-17protein level
1 19 3
2013-07-15protein level
1 12 0
2013-06-11protein level
1 12 0
2013-02-12protein level
1 10 0
2012-12-20protein level
1 9 0
2012-10-30protein level
1 10 0
2012-10-07protein level
1 10 0
2012-08-24protein level
1 9 0
2012-07-28protein level
1 9 0
2012-06-08protein level
1 9 0
2012-05-07protein level
1 9 0
2012-04-10protein level
1 9 0
2012-01-13protein level
1 5 0
2011-12-20protein level
1 5 0
2011-11-11protein level
1 5 0
2011-08-23protein level
1 5 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q969U7-1
1 10 0 29376.9439
NX_Q969U7-2
1 10 0 26304.44
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-723276,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
2 EBI-723276,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
3 EBI-723276,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder334
blood49
bone41
bone marrow41
brain24
cervix61
connective tissue6
embryonic tissue32
eye23
heart33
intestine21
kidney56
liver48
lung29
lymph67
lymph node66
mammary gland26
mouth15
muscle47
nerve64
ovary29
pancreas46
pharynx49
pituitary gland60
placenta38
prostate68
skin33
stomach73
testis75
thyroid85
uterus38
Health State
TissuesTPM*
normal32
bladder carcinoma625
breast (mammary gland) tumor42
cervical tumor86
chondrosarcoma12
colorectal tumor17
gastrointestinal tumor50
germ cell tumor18
glioma46
head and neck tumor22
kidney tumor29
leukemia63
liver tumor31
lung tumor29
lymphoma69
non-neoplasia10
ovarian tumor26
pancreatic tumor38
primitive neuroectodermal tumor of the CNS62
prostate cancer86
retinoblastoma43
skin tumor55
soft tissue/muscle tissue tumor23
uterine tumor44
Developmental Stage
TissuesTPM*
adult23
embryoid body28
blastocyst48
fetus16
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue48.9
adrenal gland48
appendix49.9
bone marrow65.1
cerebral cortex29.8
colon57.9
duodenum49.4
esophagus61.2
gallbladder61
heart muscle39.7
kidney46.6
liver30.4
lung43.7
lymph node67.8
ovary62.8
pancreas26.8
placenta51.3
prostate42.1
salivary gland33.9
skin48.3
small intestine47.9
spleen42.6
stomach44.1
testis87
thyroid gland54.9
urinary bladder73.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609702, gene) Proteasome-assembling chaperone 2; PSMG2OMIM


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