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> Protein (NX_Q969Z0)
Protein (NX_Q969Z0)
Protein
Gene SymbolTBRG4 to neXtProt (NX_Q969Z0)
DescriptionProtein TBRG4
Chromosome7
Location7p13 (45139699 ~ 45151646) to Ensembl
Sequene Features : Isoforms 2, Variants 70, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular respiration
.positive regulation of cell proliferation
.cell cycle arrest
.poly(A) RNA binding
.protein kinase activity
.mitochondrion
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 70 2
2014-09-19protein level
2 55 2
2014-05-27protein level
2 55 2
2014-02-25protein level
2 55 2
2013-12-09protein level
2 45 2
2013-11-01protein level
2 39 1
2013-09-12protein level
2 39 1
2013-08-17protein level
2 39 1
2013-07-15protein level
2 23 1
2013-06-11protein level
2 23 1
2013-02-12protein level
2 12 4
2012-12-20protein level
2 12 4
2012-10-30protein level
2 13 4
2012-10-07protein level
2 13 2
2012-08-24protein level
2 11 2
2012-07-28protein level
2 11 2
2012-06-08protein level
2 14 2
2012-05-07protein level
2 14 2
2012-04-10protein level
2 14 2
2012-01-13protein level
2 17 2
2011-12-20protein level
2 17 2
2011-11-11protein level
2 17 2
2011-08-23protein level
2 17 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q969Z0-1
7 22 0 70693.2075
NX_Q969Z0-2
0 22 0 58405.636
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-702328,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
2 EBI-702328,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
3 EBI-702328,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
4 EBI-702328,EBI-944295 MAL2  
  .N/A .N/A .extracellular exosome
.perinuclear region of cytoplasm
.membrane raft
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland303
ascites25
bladder33
blood204
bone69
bone marrow225
brain160
cervix329
connective tissue140
embryonic tissue126
esophagus49
eye90
heart122
intestine155
kidney128
liver87
lung110
lymph293
lymph node133
mammary gland79
mouth90
muscle47
nerve128
ovary147
pancreas70
parathyroid97
pituitary gland121
placenta81
prostate163
skin213
spleen224
stomach73
testis142
thymus250
thyroid64
trachea96
uterus129
vascular232
Health State
TissuesTPM*
normal19
adrenal tumor237
bladder carcinoma56
breast (mammary gland) tumor32
cervical tumor86
chondrosarcoma60
colorectal tumor151
esophageal tumor57
gastrointestinal tumor16
germ cell tumor60
glioma55
head and neck tumor7
kidney tumor29
leukemia42
liver tumor31
lung tumor9
lymphoma235
non-neoplasia51
ovarian tumor131
pancreatic tumor123
primitive neuroectodermal tumor of the CNS86
prostate cancer19
retinoblastoma21
skin tumor79
soft tissue/muscle tissue tumor15
uterine tumor99
Developmental Stage
TissuesTPM*
adult16
embryoid body14
blastocyst211
neonate64
fetus3
infant85
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue21.5
adrenal gland22.6
appendix42.1
bone marrow17.3
cerebral cortex19.8
colon39.6
duodenum38.6
esophagus32.4
gallbladder21.5
heart muscle33.9
kidney26.5
liver19.5
lung20.7
lymph node39.8
ovary27.3
pancreas14.1
placenta26.6
prostate21.2
salivary gland18.2
skin28
small intestine34.5
spleen35.7
stomach29.5
testis32.8
thyroid gland19.3
urinary bladder27.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611325, gene) Transforming growth factor-beta regulator 4; TBRG4OMIM


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