Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q96AQ6)
Protein (NX_Q96AQ6)
Protein
Gene SymbolPBXIP1 to neXtProt (NX_Q96AQ6)
DescriptionPre-B-cell leukemia transcription factor-interacting protein 1
Chromosome1
Location1q21.3 (154916552 ~ 154928599) to Ensembl
Sequene Features : Isoforms 3, Variants 88, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of transcription, DNA-templated
.cell differentiation
.multicellular organismal development
.transcription corepressor activity .microtubule
.cytosol
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 88 7
2014-09-19protein level
3 68 7
2014-05-27protein level
3 68 7
2014-02-25protein level
3 67 7
2013-12-09protein level
3 60 7
2013-11-01protein level
3 58 7
2013-09-12protein level
3 58 7
2013-08-17protein level
3 58 7
2013-07-15protein level
3 44 7
2013-06-11protein level
3 44 7
2013-02-12protein level
3 23 18
2012-12-20protein level
3 22 18
2012-10-30protein level
3 19 18
2012-10-07protein level
3 19 6
2012-08-24protein level
3 17 6
2012-07-28protein level
3 17 6
2012-06-08protein level
3 22 6
2012-05-07protein level
3 22 6
2012-04-10protein level
3 22 6
2012-01-13protein level
3 13 6
2011-12-20protein level
3 13 6
2011-11-11protein level
3 13 6
2011-08-23protein level
3 13 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96AQ6-1
0 30 0 80593.8412
NX_Q96AQ6-2
0 29 0 77636.4957
NX_Q96AQ6-3
0 25 0 72875.9166
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-740845,EBI-347996 SGTA  
  .viral process .N/A .cytoplasm
2 EBI-740845,EBI-78473 ESR1  
  .cellular response to estradiol stimulus
.epithelial cell proliferation involved in mammary gland duct elongation
.mammary gland alveolus development
  + 33 more...
.ATPase binding
.identical protein binding
.estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
  + 14 more...
.transcriptionally active chromatin
.integral component of membrane
.membrane
  + 5 more...
3 EBI-740845,EBI-395261 CCNC  
  .positive regulation of transcription from RNA polymerase II promoter
.gene expression
.Notch signaling pathway
  + 4 more...
.N/A .mediator complex
.nucleoplasm
4 EBI-740845,EBI-745369 DEF6  
  .N/A .N/A .membrane
.cell-cell junction
.plasma membrane
  + 2 more...
5 EBI-740845,EBI-399246 MORF4L1  
  .histone H2A acetylation
.histone H4 acetylation
.regulation of growth
  + 6 more...
.protein N-terminus binding
.chromatin binding
.NuA4 histone acetyltransferase complex
.Sin3 complex
.nucleoplasm
6 EBI-740845,EBI-77321 DAXX  
  .positive regulation of apoptotic signaling pathway
.positive regulation of neuron death
.negative regulation of transcription, DNA-templated
  + 13 more...
.androgen receptor binding
.protein N-terminus binding
.protein homodimerization activity
  + 10 more...
.SWI/SNF superfamily-type complex
.PML body
.cytosol
  + 5 more...
7 EBI-740845,EBI-10173939 UBQLN1  
  .regulation of autophagic vacuole assembly
.positive regulation of ER-associated ubiquitin-dependent protein catabolic process
.regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
  + 8 more...
.identical protein binding
.polyubiquitin binding
.kinase binding
.perinuclear region of cytoplasm
.protein complex
.aggresome
  + 6 more...
8 EBI-740845,EBI-712969 CCDC53  
  .protein transport .N/A .WASH complex
.intracellular membrane-bounded organelle
.actin cytoskeleton
.early endosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland182
ascites50
bladder33
blood212
bone111
bone marrow61
brain254
cervix61
connective tissue201
ear124
embryonic tissue37
esophagus99
eye105
heart122
intestine112
kidney99
liver73
lung110
lymph45
lymph node222
mammary gland66
mouth559
muscle65
nerve193
ovary78
pancreas192
parathyroid339
pituitary gland181
placenta158
prostate116
skin33
spleen468
stomach156
testis215
thymus1279
thyroid236
trachea482
uterus129
vascular116
Health State
TissuesTPM*
normal161
breast (mammary gland) tumor85
cervical tumor57
chondrosarcoma72
colorectal tumor44
esophageal tumor115
gastrointestinal tumor50
germ cell tumor273
glioma102
head and neck tumor291
kidney tumor116
leukemia264
liver tumor93
lung tumor38
lymphoma55
non-neoplasia320
ovarian tumor65
pancreatic tumor361
primitive neuroectodermal tumor of the CNS31
prostate cancer105
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor23
uterine tumor88
Developmental Stage
TissuesTPM*
adult133
embryoid body28
blastocyst65
neonate96
fetus64
infant127
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue56.5
adrenal gland92
appendix58
bone marrow23.6
cerebral cortex46.4
colon36.3
duodenum50.2
esophagus51.9
gallbladder70.4
heart muscle40.2
kidney46.9
liver21.3
lung58.1
lymph node67.4
ovary103.9
pancreas17.2
placenta35.8
prostate64.2
salivary gland35.3
skin26.7
small intestine53
spleen63.2
stomach59.2
testis43.7
thyroid gland83.6
urinary bladder72.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center