Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q96B96)
Protein (NX_Q96B96)
Protein
Gene SymbolTMEM159 to neXtProt (NX_Q96B96)
DescriptionPromethin
Chromosome16
Location16p12.3 (21169698 ~ 21191937) to Ensembl
Sequene Features : Isoforms 2, Variants 20, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .integral component of membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 20 2
2014-09-19protein level
1 14 2
2014-05-27protein level
1 14 2
2014-02-25protein level
1 14 2
2013-12-09protein level
1 10 2
2013-11-01protein level
1 10 2
2013-09-12protein level
1 10 2
2013-08-17protein level
1 10 2
2013-07-15protein level
1 7 2
2013-06-11protein level
1 7 2
2013-02-12protein level
1 6 2
2012-12-20protein level
1 7 2
2012-10-30protein level
1 7 2
2012-10-07protein level
1 7 2
2012-08-24protein level
1 7 2
2012-07-28protein level
1 7 2
2012-06-08protein level
1 7 2
2012-05-07protein level
1 6 2
2012-04-10protein level
1 6 2
2012-01-13protein level
1 5 2
2011-12-20protein level
1 5 2
2011-11-11protein level
1 5 2
2011-08-23transcript level
1 5 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96B96-1
0 4 0 17510.1293
NX_Q96B96-2
1 4 0 19973.3686
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-7055862,EBI-9304251 GAD2  
  .response to drug
.neurotransmitter biosynthetic process
.neurotransmitter secretion
  + 2 more...
.pyridoxal phosphate binding
.glutamate binding
.glutamate decarboxylase activity
.clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
.perinuclear region of cytoplasm
.presynaptic membrane
  + 7 more...
2 EBI-7055862,EBI-745535 ADCK3  
  .phosphorylation
.ubiquinone biosynthetic process
.ADP binding
.kinase activity
.ATP binding
.integral component of membrane
.mitochondrion
3 EBI-7055862,EBI-8652492 CACFD1  
  .calcium ion transmembrane transport
.membrane depolarization
.synaptic vesicle endocytosis
.synaptic transmission
.calcium channel activity .integral component of synaptic vesicle membrane
.plasma membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood16
bone13
bone marrow61
brain14
cervix20
connective tissue20
embryonic tissue28
esophagus49
eye23
heart78
intestine21
kidney23
larynx85
liver14
lung14
lymph node89
mammary gland59
muscle112
ovary29
pancreas93
placenta10
prostate63
skin56
spleen37
testis4
thyroid21
uterus30
vascular38
Health State
TissuesTPM*
normal34
breast (mammary gland) tumor64
chondrosarcoma24
colorectal tumor17
esophageal tumor57
germ cell tumor15
glioma27
head and neck tumor7
leukemia31
liver tumor10
lung tumor9
non-neoplasia10
ovarian tumor39
pancreatic tumor152
skin tumor39
uterine tumor22
Developmental Stage
TissuesTPM*
adult21
embryoid body28
blastocyst16
fetus25
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.6
adrenal gland25.8
appendix11.7
bone marrow4.4
cerebral cortex4.5
colon24.6
duodenum9.2
esophagus57.7
gallbladder40.1
heart muscle87.5
kidney20.4
liver2.5
lung17.8
lymph node23.3
ovary65.6
pancreas7
placenta7.2
prostate24.1
salivary gland24.5
skin67
small intestine9.8
spleen8.6
stomach18.3
testis15.2
thyroid gland17.8
urinary bladder57.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611304, gene) Transmembrane protein 159; TMEM159OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center