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> Protein (NX_Q96BD8)
Protein (NX_Q96BD8)
Protein
Gene SymbolSKA1 to neXtProt (NX_Q96BD8)
DescriptionSpindle and kinetochore-associated protein 1
Chromosome18
Location18q21.1 (47901365 ~ 47920543) to Ensembl
Sequene Features : Isoforms 2, Variants 27, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.regulation of microtubule polymerization or depolymerization
.small GTPase mediated signal transduction
  + 3 more...
.microtubule binding .microtubule cytoskeleton
.spindle microtubule
.cytosol
.condensed chromosome outer kinetochore
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 27 1
2014-09-19protein level
2 22 1
2014-05-27protein level
2 22 1
2014-02-25protein level
2 21 1
2013-12-09protein level
2 19 1
2013-11-01protein level
2 17 1
2013-09-12protein level
2 17 1
2013-08-17protein level
2 17 1
2013-07-15protein level
2 12 0
2013-06-11protein level
2 12 0
2013-02-12protein level
2 8 2
2012-12-20protein level
2 8 2
2012-10-30protein level
2 9 2
2012-10-07protein level
2 9 1
2012-08-24protein level
2 9 1
2012-07-28protein level
2 9 1
2012-06-08protein level
2 9 1
2012-05-07protein level
2 7 1
2012-04-10protein level
2 7 1
2012-01-13protein level
2 3 1
2011-12-20protein level
2 3 1
2011-11-11protein level
2 3 1
2011-08-23protein level
2 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96BD8-1
4 8 0 29465.2643
NX_Q96BD8-2
1 8 0 24374.7494
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-741854,EBI-6872807 SYCE1  
  .cell division
.synaptonemal complex assembly
.N/A .central element
2 EBI-741854,EBI-1773994 SKA2  
  .cell division
.regulation of microtubule polymerization or depolymerization
.small GTPase mediated signal transduction
  + 3 more...
.microtubule binding .spindle microtubule
.cytosol
.condensed chromosome outer kinetochore
3 EBI-741854,EBI-465781 BLOC1S6  
  .membrane fusion
.membrane organization
.positive regulation of pigment cell differentiation
  + 12 more...
.actin filament binding
.protein homodimerization activity
.identical protein binding
.syntaxin binding
.BLOC-1 complex
.transport vesicle
.extrinsic component of membrane
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
blood49
bone marrow61
brain5
cervix82
embryonic tissue4
eye9
intestine12
kidney14
liver53
lung17
lymph67
lymph node44
mammary gland26
ovary19
pancreas9
pharynx49
placenta35
prostate31
salivary gland98
skin9
testis20
thymus25
tonsil117
uterus12
vascular19
Health State
TissuesTPM*
normal12
adrenal tumor237
cervical tumor57
colorectal tumor8
germ cell tumor53
glioma18
kidney tumor29
leukemia74
liver tumor114
lung tumor29
lymphoma41
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS23
prostate cancer9
retinoblastoma21
skin tumor15
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult16
blastocyst16
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix3.3
bone marrow9.4
colon2.6
duodenum2.1
esophagus2
lymph node6.6
placenta1.8
skin1.2
small intestine1.6
spleen1
stomach1.2
testis6.5
urinary bladder1.4
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastHigh
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusMedium
fallopian tubeHigh
gallbladderMedium
heart muscleMedium
hippocampusLow
kidneyHigh
lateral ventricleLow
liverHigh
lungMedium
lymph nodeHigh
nasopharynxHigh
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineHigh
smooth muscleMedium
soft tissue 1High
soft tissue 2High
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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