Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q96BR1)
Protein (NX_Q96BR1)
Protein
Gene SymbolSGK3 to neXtProt (NX_Q96BR1)
DescriptionSerine/threonine-protein kinase Sgk3
Chromosome8
Location8q13.1 (67624653 ~ 67774257) to Ensembl
Sequene Features : Isoforms 2, Variants 39, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transmembrane transport
.regulation of sequence-specific DNA binding transcription factor activity
.regulation of cell proliferation
  + 5 more...
.phosphatidylinositol binding
.chloride channel regulator activity
.sodium channel regulator activity
  + 5 more...
.recycling endosome
.cytoplasmic membrane-bounded vesicle
.cytosol
.early endosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 39 4
2014-09-19protein level
2 31 4
2014-05-27protein level
2 31 4
2014-02-25protein level
2 31 4
2013-12-09protein level
2 27 4
2013-11-01protein level
2 27 4
2013-09-12protein level
2 27 4
2013-08-17protein level
2 27 4
2013-07-15protein level
2 19 4
2013-06-11protein level
2 19 4
2013-02-12protein level
2 8 8
2012-12-20protein level
2 9 8
2012-10-30protein level
2 10 8
2012-10-07protein level
2 10 4
2012-08-24protein level
2 10 4
2012-07-28protein level
2 10 4
2012-06-08protein level
2 18 4
2012-05-07protein level
2 15 4
2012-04-10protein level
2 15 4
2012-01-13protein level
2 14 4
2011-12-20protein level
2 14 4
2011-11-11protein level
2 14 4
2011-08-23protein level
1 14 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96BR1-1
2 16 0 57071.9902
NX_Q96BR1-2
1 16 0 53272.1221
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2801236,EBI-1564678 ITCH  
  .regulation of protein deubiquitination
.protein K48-linked ubiquitination
.protein K63-linked ubiquitination
  + 21 more...
.ubiquitin protein ligase activity
.CXCR chemokine receptor binding
.ribonucleoprotein complex binding
  + 2 more...
.extracellular exosome
.cytoplasmic vesicle
.membrane
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood32
bone27
bone marrow20
brain32
connective tissue20
ear62
embryonic tissue4
eye19
intestine12
kidney28
liver48
lung5
lymph22
mammary gland46
mouth45
pancreas23
parathyroid48
pharynx24
pituitary gland60
placenta21
prostate26
salivary gland49
skin18
spleen56
stomach20
testis22
thymus37
thyroid42
trachea57
uterus12
vascular19
Health State
TissuesTPM*
normal20
breast (mammary gland) tumor53
chondrosarcoma24
colorectal tumor8
gastrointestinal tumor16
head and neck tumor37
kidney tumor14
liver tumor83
lymphoma41
non-neoplasia72
pancreatic tumor19
prostate cancer38
uterine tumor11
Developmental Stage
TissuesTPM*
adult26
embryoid body14
neonate96
fetus12
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.2
adrenal gland6.5
appendix11.4
bone marrow5.9
cerebral cortex8.6
colon11.6
duodenum10
esophagus8.4
gallbladder10
heart muscle4.5
kidney13.9
liver7.5
lung9.3
lymph node9.4
ovary9.7
pancreas7.9
placenta5.9
prostate7.4
salivary gland5.7
skin16
small intestine11.4
spleen9.3
stomach8.7
testis11.6
thyroid gland20.1
urinary bladder7.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607591, gene) Serum/glucocorticoid-regulated kinase-like protein; SGKLOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center