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| Protein |
|
| Gene Symbol | SGK3 to neXtProt (NX_Q96BR1) |
| Description | Serine/threonine-protein kinase Sgk3 |
| Chromosome | 8 |
| Location | 8q13.1 (67624653 ~ 67774257) to Ensembl |
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Sequene Features : Isoforms 2, Variants 39, PTMs 4 to neXtProt Sequence Features
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|
Gene
Ontologies |
| GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
.transmembrane transport
.regulation of sequence-specific DNA binding transcription factor activity
.regulation of cell proliferation
+ 5 more... |
.phosphatidylinositol binding
.chloride channel regulator activity
.sodium channel regulator activity
+ 5 more... |
.recycling endosome
.cytoplasmic membrane-bounded vesicle
.cytosol
.early endosome |
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| |
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| Proteomic Evidences |
|
| |
|
| Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
|
| 2015-01-01 | | protein level | | | | | | | 2 |
| 39 |
| 4 |
|
| 2014-09-19 | | protein level | | | | | | | 2 |
| 31 |
| 4 |
|
| 2014-05-27 | | protein level | | | | | | | 2 |
| 31 |
| 4 |
|
| 2014-02-25 | | protein level | | | | | | | 2 |
| 31 |
| 4 |
|
| 2013-12-09 | | protein level | | | | | | | 2 |
| 27 |
| 4 |
|
| 2013-11-01 | | protein level | | | | | | | 2 |
| 27 |
| 4 |
|
| 2013-09-12 | | protein level | | | | | | | 2 |
| 27 |
| 4 |
|
| 2013-08-17 | | protein level | | | | | | | 2 |
| 27 |
| 4 |
|
| 2013-07-15 | | protein level | | | | | | | 2 |
| 19 |
| 4 |
|
| 2013-06-11 | | protein level | | | | | | | 2 |
| 19 |
| 4 |
|
| 2013-02-12 | | protein level | | | | | | | 2 |
| 8 |
| 8 |
|
| 2012-12-20 | | protein level | | | | | | | 2 |
| 9 |
| 8 |
|
| 2012-10-30 | | protein level | | | | | | | 2 |
| 10 |
| 8 |
|
| 2012-10-07 | | protein level | | | | | | | 2 |
| 10 |
| 4 |
|
| 2012-08-24 | | protein level | | | | | | | 2 |
| 10 |
| 4 |
|
| 2012-07-28 | | protein level | | | | | | | 2 |
| 10 |
| 4 |
|
| 2012-06-08 | | protein level | | | | | | | 2 |
| 18 |
| 4 |
|
| 2012-05-07 | | protein level | | | | | | | 2 |
| 15 |
| 4 |
|
| 2012-04-10 | | protein level | | | | | | | 2 |
| 15 |
| 4 |
|
| 2012-01-13 | | protein level | | | | | | | 2 |
| 14 |
| 4 |
|
| 2011-12-20 | | protein level | | | | | | | 2 |
| 14 |
| 4 |
|
| 2011-11-11 | | protein level | | | | | | | 2 |
| 14 |
| 4 |
|
| 2011-08-23 | | protein level | | | | | | | 1 |
| 14 |
| 4 |
|
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| |
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| Protein Isoforms |
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| |
| |
|
| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
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| Interacting Partners |
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|
| No. |
Exp. ref. |
Symbol |
|
PE |
Pr |
Ab |
Di |
|
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
| 1 |
EBI-2801236,EBI-1564678 |
ITCH |
|
| | | | |
.regulation of protein deubiquitination
.protein K48-linked ubiquitination
.protein K63-linked ubiquitination
+ 21 more... |
.ubiquitin protein ligase activity
.CXCR chemokine receptor binding
.ribonucleoprotein complex binding
+ 2 more... |
.extracellular exosome
.cytoplasmic vesicle
.membrane
+ 5 more... |
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|
| |
|
| EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
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| |
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| Body Sites | |
| Tissues | TPM* | |
|
| blood | 32 | |
| bone | 27 | |
| bone marrow | 20 | |
| brain | 32 | |
| connective tissue | 20 | |
| ear | 62 | |
| embryonic tissue | 4 | |
| eye | 19 | |
| intestine | 12 | |
| kidney | 28 | |
| liver | 48 | |
| lung | 5 | |
| lymph | 22 | |
| mammary gland | 46 | |
| mouth | 45 | |
| pancreas | 23 | |
| parathyroid | 48 | |
| pharynx | 24 | |
| pituitary gland | 60 | |
| placenta | 21 | |
| prostate | 26 | |
| salivary gland | 49 | |
| skin | 18 | |
| spleen | 56 | |
| stomach | 20 | |
| testis | 22 | |
| thymus | 37 | |
| thyroid | 42 | |
| trachea | 57 | |
| uterus | 12 | |
| vascular | 19 | |
|
| Health State | |
| Tissues | TPM* | |
|
| normal | 20 | |
| breast (mammary gland) tumor | 53 | |
| chondrosarcoma | 24 | |
| colorectal tumor | 8 | |
| gastrointestinal tumor | 16 | |
| head and neck tumor | 37 | |
| kidney tumor | 14 | |
| liver tumor | 83 | |
| lymphoma | 41 | |
| non-neoplasia | 72 | |
| pancreatic tumor | 19 | |
| prostate cancer | 38 | |
| uterine tumor | 11 | |
|
| Developmental Stage | |
| Tissues | TPM* | |
|
| adult | 26 | |
| embryoid body | 14 | |
| neonate | 96 | |
| fetus | 12 | |
| juvenile | 17 | |
|
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
| |
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| Expression level of Protein (ref. Human Protein Atlas) |
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| RNA-Seq. | |
| Tissues | FPKM | |
|
| adipose tissue | 5.2 | |
| adrenal gland | 6.5 | |
| appendix | 11.4 | |
| bone marrow | 5.9 | |
| cerebral cortex | 8.6 | |
| colon | 11.6 | |
| duodenum | 10 | |
| esophagus | 8.4 | |
| gallbladder | 10 | |
| heart muscle | 4.5 | |
| kidney | 13.9 | |
| liver | 7.5 | |
| lung | 9.3 | |
| lymph node | 9.4 | |
| ovary | 9.7 | |
| pancreas | 7.9 | |
| placenta | 5.9 | |
| prostate | 7.4 | |
| salivary gland | 5.7 | |
| skin | 16 | |
| small intestine | 11.4 | |
| spleen | 9.3 | |
| stomach | 8.7 | |
| testis | 11.6 | |
| thyroid gland | 20.1 | |
| urinary bladder | 7.7 | |
|
| Cancer | |
| Tumor | Number of patients and Staining levels | |
| breast cancer | |
| carcinoid | |
| cervical cancer | |
| colorectal cancer | |
| endometrial cancer | |
| glioma | |
| head and neck cancer | |
| liver cancer | |
| lung cancer | |
| lymphoma | |
| melanoma | |
| ovarian cancer | |
| pancreatic cancer | |
| prostate cancer | |
| renal cancer | |
| skin cancer | |
| stomach cancer | |
| testis cancer | |
| thyroid cancer | |
| urothelial cancer | |
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| RNA-seq colour codes |
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Highly expressed RNAs (FPKM >50) | |
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Moderately expressed RNAs (50> FPKM >10) | |
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Lower expressed RNAs (10> FPKM >1) | |
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The lowest expressed RNAs (FPKM value of 0 or 1) |
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| Staining level colour codes |
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Highly expressed protein | |
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Moderately expressed protein | |
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Lower expressed protein | |
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Not Detected |
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| Disease |
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| No. | Disease Description | Ref. |
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| 1 | (*607591, gene) Serum/glucocorticoid-regulated kinase-like protein; SGKL | OMIM |
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> Protein (NX_Q96BR1)