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> Protein (NX_Q96C00)
Protein (NX_Q96C00)
Protein
Gene SymbolZBTB9 to neXtProt (NX_Q96C00)
DescriptionZinc finger and BTB domain-containing protein 9
Chromosome6
Location6p21.32 (33422356 ~ 33425325) to Ensembl
Sequene Features : Isoforms 1, Variants 49, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 49 2
2014-09-19protein level
1 33 2
2014-05-27protein level
1 33 2
2014-02-25protein level
1 17 2
2013-12-09protein level
1 7 2
2013-11-01protein level
1 7 2
2013-09-12protein level
1 7 2
2013-08-17protein level
1 7 2
2013-07-15protein level
1 7 2
2013-06-11protein level
1 7 2
2013-02-12protein level
1 7 2
2012-12-20protein level
1 6 2
2012-10-30protein level
1 8 2
2012-10-07protein level
1 8 2
2012-08-24protein level
1 8 2
2012-07-28protein level
1 8 2
2012-06-08protein level
1 9 2
2012-05-07protein level
1 9 2
2012-04-10protein level
1 9 2
2012-01-13protein level
1 3 2
2011-12-20protein level
1 3 2
2011-11-11protein level
1 3 1
2011-08-23protein level
1 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96C00-1
18 0 1 50570.2975
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-395708,EBI-398610 EIF4E2  
  .cytokine-mediated signaling pathway
.negative regulation of translation
.in utero embryonic development
.poly(A) RNA binding
.ubiquitin protein ligase binding
.translation factor activity, RNA binding
  + 2 more...
.mRNA cap binding complex
.cytosol
2 EBI-395708,EBI-740402 DTNB  
  .N/A .zinc ion binding .synapse
.cytoplasm
3 EBI-395708,EBI-10176379 KRTAP12-2  
  .N/A .N/A .keratin filament
4 EBI-395708,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
5 EBI-395708,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
6 EBI-395708,EBI-2339219 EHHADH  
  .fatty acid beta-oxidation
.internal protein amino acid acetylation
.coenzyme binding
.enzyme binding
.receptor binding
  + 3 more...
.cytosol
.peroxisome
.mitochondrion
7 EBI-395708,EBI-714158 PIN1  
  .negative regulation of cell motility
.negative regulation of ERK1 and ERK2 cascade
.regulation of pathway-restricted SMAD protein phosphorylation
  + 11 more...
.phosphothreonine binding
.phosphoserine binding
.GTPase activating protein binding
  + 2 more...
.midbody
.nuclear speck
.cytoplasm
  + 2 more...
8 EBI-395708,EBI-374900 MCM6  
  .DNA strand elongation involved in DNA replication
.DNA replication initiation
.DNA unwinding involved in DNA replication
  + 3 more...
.identical protein binding
.ATP binding
.single-stranded DNA binding
.DNA helicase activity
.MCM complex
.nucleoplasm
.nucleus
9 EBI-395708,EBI-742828 LASP1  
  .positive regulation of signal transduction
.ion transport
.ion transmembrane transporter activity
.zinc ion binding
.SH3/SH2 adaptor activity
.extracellular exosome
.cortical actin cytoskeleton
.focal adhesion
10 EBI-395708,EBI-749432 DYRK2  
  .negative regulation of NFAT protein import into nucleus
.positive regulation of glycogen biosynthetic process
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
  + 4 more...
.ubiquitin binding
.manganese ion binding
.ATP binding
  + 4 more...
.ribonucleoprotein complex
.cytoplasm
.nucleoplasm
  + 2 more...
11 EBI-395708,EBI-746981 TSR2  
  .maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) .N/A .nucleus
12 EBI-395708,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
13 EBI-395708,EBI-399246 MORF4L1  
  .histone H2A acetylation
.histone H4 acetylation
.regulation of growth
  + 6 more...
.protein N-terminus binding
.chromatin binding
.NuA4 histone acetyltransferase complex
.Sin3 complex
.nucleoplasm
14 EBI-395708,EBI-714599 PIN4  
  .rRNA processing .poly(A) RNA binding
.peptidyl-prolyl cis-trans isomerase activity
.double-stranded DNA binding
  + 2 more...
.extracellular exosome
.preribosome
.spindle
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
blood32
bone41
brain18
connective tissue6
embryonic tissue32
eye47
heart11
intestine12
kidney14
larynx85
liver9
lung26
lymph node11
mammary gland26
mouth45
muscle37
ovary9
pancreas4
prostate5
skin14
spleen18
stomach10
testis18
thymus12
trachea19
uterus17
Health State
TissuesTPM*
normal18
breast (mammary gland) tumor10
chondrosarcoma24
colorectal tumor8
gastrointestinal tumor8
germ cell tumor30
glioma18
head and neck tumor37
kidney tumor14
leukemia42
liver tumor10
lung tumor48
lymphoma13
non-neoplasia20
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS62
retinoblastoma21
skin tumor15
soft tissue/muscle tissue tumor31
Developmental Stage
TissuesTPM*
adult15
embryoid body14
blastocyst32
fetus25
infant85
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.8
adrenal gland3.8
appendix4.4
bone marrow1.4
cerebral cortex4.1
colon3.3
duodenum3.4
esophagus3.2
gallbladder3.4
heart muscle2.7
kidney4.4
liver1.4
lung3.7
lymph node4.9
ovary7.6
pancreas1.5
placenta3.7
prostate3.3
salivary gland3.1
skin4.9
small intestine2.7
spleen3.4
stomach3.1
testis7.3
thyroid gland4.5
urinary bladder4.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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