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> Protein (NX_Q96C03)
Protein (NX_Q96C03)
Protein
Gene SymbolMIEF2 to neXtProt (NX_Q96C03)
DescriptionMitochondrial dynamics protein MID49
Chromosome17
Location17p11.2 (18163848 ~ 18169866) to Ensembl
Sequene Features : Isoforms 3, Variants 36, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of protein targeting to membrane
.positive regulation of mitochondrial fission
.positive regulation of protein homooligomerization
.mitochondrion organization
.N/A .integral component of membrane
.mitochondrial outer membrane
.mitochondrion
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 36 3
2014-09-19protein level
3 49 3
2014-05-27protein level
3 48 3
2014-02-25protein level
3 48 3
2013-12-09protein level
3 32 3
2013-11-01protein level
3 31 2
2013-09-12protein level
3 31 2
2013-08-17protein level
3 31 2
2013-07-15protein level
2 28 1
2013-06-11protein level
2 28 1
2013-02-12protein level
2 19 2
2012-12-20protein level
2 17 2
2012-10-30protein level
2 20 2
2012-10-07protein level
2 20 1
2012-08-24protein level
2 20 1
2012-07-28protein level
2 21 1
2012-06-08protein level
2 22 1
2012-05-07protein level
2 21 1
2012-04-10protein level
2 21 1
2012-01-13protein level
2 8 1
2011-12-20protein level
2 8 1
2011-11-11protein level
2 8 1
2011-08-23protein level
2 8 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96C03-1
0 19 0 49237.8498
NX_Q96C03-2
5 2 0 20546.4643
NX_Q96C03-3
2 19 0 50450.4384
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-750153,EBI-724571 DNM1L  
  .positive regulation of intrinsic apoptotic signaling pathway
.regulation of mitochondrion degradation
.regulation of peroxisome organization
  + 22 more...
.protein homodimerization activity
.identical protein binding
.ubiquitin protein ligase binding
  + 3 more...
.perinuclear region of cytoplasm
.protein complex
.intracellular membrane-bounded organelle
  + 11 more...
2 EBI-750153,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
3 EBI-750153,EBI-712367 RABAC1  
  .N/A .identical protein binding .cell junction
.integral component of membrane
.membrane
  + 3 more...
4 EBI-750153,EBI-741480 UBQLN1  
  .regulation of autophagic vacuole assembly
.positive regulation of ER-associated ubiquitin-dependent protein catabolic process
.regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
  + 8 more...
.identical protein binding
.polyubiquitin binding
.kinase binding
.perinuclear region of cytoplasm
.protein complex
.aggresome
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder33
blood49
bone13
brain44
embryonic tissue23
eye23
heart11
intestine12
kidney28
liver4
lung14
mammary gland13
mouth45
muscle28
nerve64
ovary49
pancreas4
placenta10
prostate42
salivary gland49
skin18
spleen18
stomach10
testis9
thymus100
trachea19
uterus21
vascular38
Health State
TissuesTPM*
normal27
breast (mammary gland) tumor21
chondrosarcoma12
gastrointestinal tumor16
germ cell tumor56
glioma18
head and neck tumor7
kidney tumor14
leukemia31
liver tumor10
lung tumor19
non-neoplasia41
primitive neuroectodermal tumor of the CNS31
prostate cancer19
skin tumor15
soft tissue/muscle tissue tumor31
uterine tumor22
Developmental Stage
TissuesTPM*
adult18
embryoid body28
blastocyst16
fetus30
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.4
adrenal gland5
appendix2.8
bone marrow1.7
cerebral cortex6.2
colon4.3
duodenum4.2
esophagus4.5
gallbladder3.9
heart muscle9.7
kidney8.2
liver2.9
lung6
lymph node3.7
ovary9.4
pancreas3.3
placenta4.6
prostate7.4
salivary gland7
skin6.7
small intestine5
spleen5.2
stomach4.6
testis3.5
thyroid gland6.8
urinary bladder3.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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