Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q96CM8)
Protein (NX_Q96CM8)
Protein
Gene SymbolACSF2 to neXtProt (NX_Q96CM8)
DescriptionAcyl-CoA synthetase family member 2, mitochondrial
Chromosome17
Location17q21.33 (48503519 ~ 48552206) to Ensembl
Sequene Features : Isoforms 4, Variants 79, PTMs 15 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.fatty acid metabolic process .ligase activity
.ATP binding
.mitochondrion
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 79 15
2014-09-19protein level
4 52 15
2014-05-27protein level
1 51 15
2014-02-25protein level
1 51 10
2013-12-09protein level
1 36 10
2013-11-01protein level
1 34 10
2013-09-12protein level
1 34 3
2013-08-17protein level
1 34 3
2013-07-15protein level
1 24 3
2013-06-11protein level
1 24 3
2013-02-12protein level
1 13 1
2012-12-20protein level
1 12 1
2012-10-30protein level
1 16 1
2012-10-07protein level
1 16 1
2012-08-24protein level
1 16 1
2012-07-28protein level
1 16 1
2012-06-08protein level
1 16 1
2012-05-07protein level
1 15 1
2012-04-10protein level
1 15 1
2012-01-13protein level
1 7 1
2011-12-20protein level
1 7 1
2011-11-11protein level
1 7 1
2011-08-23protein level
1 7 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96CM8-1
0 26 0 68080.5738
NX_Q96CM8-2
1 26 0 70576.8068
NX_Q96CM8-3
1 25 0 66754.8433
NX_Q96CM8-4
1 19 0 50846.6197
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2876502,EBI-714543 ARL6IP1  
  .cotranslational protein targeting to membrane .N/A .integral component of membrane
.membrane
.cytosol
.Sec61 translocon complex
2 EBI-2876502,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
3 EBI-2876502,EBI-2548702 CMTM5  
  .negative regulation of myoblast differentiation
.chemotaxis
.N/A .integral component of membrane
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland971
ascites75
bladder234
blood106
bone41
bone marrow143
brain79
cervix144
connective tissue80
embryonic tissue51
eye19
heart134
intestine103
kidney612
liver102
lung65
lymph node55
mammary gland79
mouth75
muscle65
ovary39
pancreas9
pituitary gland60
placenta84
prostate68
skin47
spleen149
stomach62
testis50
thymus301
thyroid193
trachea193
uterus68
vascular38
Health State
TissuesTPM*
normal116
bladder carcinoma284
breast (mammary gland) tumor128
cervical tumor86
chondrosarcoma48
colorectal tumor44
gastrointestinal tumor42
germ cell tumor53
glioma139
head and neck tumor59
kidney tumor159
leukemia211
liver tumor156
lung tumor38
lymphoma69
non-neoplasia134
pancreatic tumor19
primitive neuroectodermal tumor of the CNS94
prostate cancer9
skin tumor63
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult74
embryoid body42
blastocyst32
neonate96
fetus44
juvenile251
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue27.7
adrenal gland67.2
appendix12.4
bone marrow5.2
cerebral cortex6.2
colon39.3
duodenum42.3
esophagus10
gallbladder17.4
heart muscle20.1
kidney174.7
liver35.5
lung41.2
lymph node15.9
ovary30.4
pancreas11.2
placenta25.8
prostate19.7
salivary gland21.6
skin43.2
small intestine44.3
spleen18.2
stomach30.2
testis9.8
thyroid gland69
urinary bladder28.4
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bronchusLow
cerebral cortexLow
cervix, uterineLow
colonHigh
duodenumHigh
endometrium 2Medium
epididymisMedium
esophagusLow
gallbladderHigh
heart muscleMedium
hippocampusLow
kidneyHigh
liverLow
lungLow
lymph nodeMedium
nasopharynxHigh
oral mucosaLow
pancreasLow
parathyroid glandMedium
placentaHigh
prostateLow
rectumHigh
salivary glandMedium
seminal vesicleHigh
skin 1Low
skin 2Low
small intestineHigh
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandHigh
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610465, gene) Acyl-coa synthetase family, member 2; ACSF2OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center