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> Protein (NX_Q96DN0)
Protein (NX_Q96DN0)
Protein
Gene SymbolERP27 to neXtProt (NX_Q96DN0)
DescriptionEndoplasmic reticulum resident protein 27
Chromosome12
Location12p12.3 (15066969 ~ 15092016) to Ensembl
Sequene Features : Isoforms 1, Variants 44, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .endoplasmic reticulum lumen
.endoplasmic reticulum
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 44 0
2014-09-19protein level
1 34 0
2014-05-27protein level
1 34 0
2014-02-25protein level
1 34 0
2013-12-09protein level
1 28 0
2013-11-01protein level
1 23 0
2013-09-12protein level
1 23 0
2013-08-17protein level
1 23 0
2013-07-15protein level
1 18 0
2013-06-11protein level
1 18 0
2013-02-12protein level
1 11 0
2012-12-20protein level
1 11 0
2012-10-30protein level
1 12 0
2012-10-07protein level
1 12 0
2012-08-24protein level
1 8 0
2012-07-28protein level
1 8 0
2012-06-08protein level
1 14 0
2012-05-07protein level
1 14 0
2012-04-10protein level
1 14 0
2012-01-13protein level
1 10 0
2011-12-20protein level
1 10 0
2011-11-11protein level
1 10 0
2011-08-23protein level
1 10 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96DN0-1
8 0 0 30460.3975
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-953772,EBI-347996 SGTA  
  .viral process .N/A .cytoplasm
2 EBI-953772,EBI-358607 EEF1D  
  .cellular response to ionizing radiation
.cellular protein metabolic process
.positive regulation of I-kappaB kinase/NF-kappaB signaling
  + 8 more...
.activating transcription factor binding
.heat shock protein binding
.translation factor activity, RNA binding
  + 3 more...
.eukaryotic translation elongation factor 1 complex
.cytosol
.cytoplasm
  + 2 more...
3 EBI-953772,EBI-741480 UBQLN1  
  .regulation of autophagic vacuole assembly
.positive regulation of ER-associated ubiquitin-dependent protein catabolic process
.regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
  + 8 more...
.identical protein binding
.polyubiquitin binding
.kinase binding
.perinuclear region of cytoplasm
.protein complex
.aggresome
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
blood32
bone13
bone marrow41
cervix20
embryonic tissue18
intestine17
kidney18
lung5
lymph node22
mammary gland26
ovary39
pancreas23
parathyroid145
placenta14
thyroid21
uterus17
Health State
TissuesTPM*
normal9
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor8
gastrointestinal tumor16
head and neck tumor7
leukemia52
ovarian tumor39
pancreatic tumor9
soft tissue/muscle tissue tumor7
uterine tumor44
Developmental Stage
TissuesTPM*
adult11
blastocyst16
fetus16
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix3.3
bone marrow2.3
duodenum1
gallbladder1
kidney18.2
lung9
lymph node3.6
ovary1.2
pancreas570.8
placenta2.7
prostate1.3
salivary gland1.5
spleen2.4
stomach3.5
thyroid gland5.7
urinary bladder21.2
Tissues
TissuesExpression level
pancreasHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610642, gene) Endoplasmic reticulum protein, 27-kd; ERP27OMIM


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