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> Protein (NX_Q96DT7)
Protein (NX_Q96DT7)
Protein
Gene SymbolZBTB10 to neXtProt (NX_Q96DT7)
DescriptionZinc finger and BTB domain-containing protein 10
Chromosome8
Location8q21.13 (81397854 ~ 81438500) to Ensembl
Sequene Features : Isoforms 4, Variants 64, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 64 4
2014-09-19protein level
4 50 4
2014-05-27protein level
4 50 4
2014-02-25protein level
4 49 3
2013-12-09protein level
4 39 3
2013-11-01protein level
4 39 2
2013-09-12protein level
4 39 2
2013-08-17protein level
4 39 2
2013-07-15protein level
4 24 2
2013-06-11protein level
4 24 2
2013-02-12protein level
4 10 15
2012-12-20protein level
4 9 15
2012-10-30protein level
4 14 15
2012-10-07protein level
4 14 4
2012-08-24protein level
4 14 4
2012-07-28protein level
4 13 4
2012-06-08protein level
4 18 4
2012-05-07protein level
4 14 4
2012-04-10protein level
4 14 4
2012-01-13protein level
4 10 4
2011-12-20protein level
4 10 4
2011-11-11protein level
4 10 4
2011-08-23protein level
4 10 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96DT7-1
0 41 0 94834.5265
NX_Q96DT7-2
1 38 0 92253.2482
NX_Q96DT7-3
1 32 0 77374.9
NX_Q96DT7-4
2 26 0 64899.3164
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10235384,EBI-399257 MORF4L2  
  .positive regulation of striated muscle cell differentiation
.positive regulation of transcription from RNA polymerase II promoter
.regulation of growth
  + 4 more...
.N/A .nucleolus
.nucleoplasm
2 EBI-10235384,EBI-9679267 MOB3C  
  .N/A .metal ion binding .N/A
3 EBI-10235384,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
4 EBI-10235384,EBI-399246 MORF4L1  
  .histone H2A acetylation
.histone H4 acetylation
.regulation of growth
  + 6 more...
.protein N-terminus binding
.chromatin binding
.NuA4 histone acetyltransferase complex
.Sin3 complex
.nucleoplasm
5 EBI-10235384,EBI-372521 LSM4  
  .activation of mitophagy in response to mitochondrial depolarization
.exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
  + 4 more...
.poly(A) RNA binding .small nuclear ribonucleoprotein complex
.cytosol
.U6 snRNP
.spliceosomal complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
blood16
bone13
brain19
connective tissue6
embryonic tissue61
eye33
intestine25
kidney28
liver4
lung8
lymph22
lymph node44
mammary gland13
muscle65
nerve128
ovary19
pancreas9
placenta38
prostate63
skin28
testis34
thymus37
uterus12
vascular38
Health State
TissuesTPM*
normal29
adrenal tumor79
chondrosarcoma24
colorectal tumor26
germ cell tumor37
glioma18
kidney tumor43
leukemia21
lung tumor19
lymphoma27
non-neoplasia10
ovarian tumor52
prostate cancer67
retinoblastoma21
uterine tumor11
Developmental Stage
TissuesTPM*
adult22
embryoid body85
blastocyst32
fetus44
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.7
adrenal gland8
appendix4.8
bone marrow14.5
cerebral cortex6.7
colon8
duodenum1.7
esophagus3.5
gallbladder7.8
heart muscle5.3
kidney9.1
liver12.5
lung5.8
lymph node4.7
ovary11.9
pancreas6.5
placenta15.8
prostate13.4
salivary gland5.2
skin1.2
small intestine1.4
spleen6.5
stomach4.2
testis11.7
thyroid gland9.2
urinary bladder6.2
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverMedium
lungHigh
lymph nodeHigh
nasopharynxHigh
oral mucosaHigh
ovaryHigh
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleMedium
skeletal muscleHigh
skin 1High
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1High
soft tissue 2High
spleenMedium
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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