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> Protein (NX_Q96EN8)
Protein (NX_Q96EN8)
Protein
Gene SymbolMOCOS to neXtProt (NX_Q96EN8)
DescriptionMolybdenum cofactor sulfurase
Chromosome18
Location18q12.2 (33767482 ~ 33852120) to Ensembl
Sequene Features : Isoforms 1, Variants 133, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.small molecule metabolic process
.molybdopterin cofactor metabolic process
.molybdopterin cofactor biosynthetic process
  + 3 more...
.pyridoxal phosphate binding
.molybdenum ion binding
.lyase activity
  + 2 more...
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 133 3
2014-09-19protein level
1 113 3
2014-05-27protein level
1 113 3
2014-02-25protein level
1 113 3
2013-12-09protein level
1 91 3
2013-11-01protein level
1 88 3
2013-09-12protein level
1 88 3
2013-08-17protein level
1 88 3
2013-07-15protein level
1 72 3
2013-06-11protein level
1 72 3
2013-02-12protein level
1 43 3
2012-12-20protein level
1 42 3
2012-10-30protein level
1 51 3
2012-10-07protein level
1 51 3
2012-08-24protein level
1 49 3
2012-07-28protein level
1 49 3
2012-06-08protein level
1 51 3
2012-05-07protein level
1 46 3
2012-04-10protein level
1 46 3
2012-01-13protein level
1 27 3
2011-12-20protein level
1 27 3
2011-11-11protein level
1 27 3
2011-08-23protein level
1 27 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96EN8-1
46 0 0 98057.6459
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1220583,EBI-747655 PARVA  
  .smooth muscle cell chemotaxis
.actin-mediated cell contraction
.cilium morphogenesis
  + 8 more...
.N/A .Z disc
.actin cytoskeleton
.focal adhesion
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
bone13
brain2
cervix144
connective tissue20
esophagus49
intestine30
larynx42
liver14
lung20
mammary gland6
placenta10
prostate15
salivary gland49
skin4
Health State
TissuesTPM*
normal3
breast (mammary gland) tumor10
cervical tumor202
chondrosarcoma24
colorectal tumor62
esophageal tumor57
gastrointestinal tumor8
glioma27
head and neck tumor7
liver tumor10
lung tumor68
skin tumor7
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult9
fetus1
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2
adrenal gland9.3
appendix2.1
colon2.1
duodenum5.6
esophagus2.5
gallbladder2.2
kidney1.1
liver11.6
lung2.2
ovary4
placenta1.2
prostate1.1
skin1.4
small intestine6.2
stomach1.7
testis1.5
thyroid gland1.5
urinary bladder2.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(-603592, phenotype) Xanthinuria, type iiOMIM
2(*613274, gene) Molybdenum cofactor sulfurase; MOCOSOMIM


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