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> Protein (NX_Q96EQ8)
Protein (NX_Q96EQ8)
Protein
Gene SymbolRNF125 to neXtProt (NX_Q96EQ8)
DescriptionE3 ubiquitin-protein ligase RNF125
Chromosome18
Location18q12.1 (29598335 ~ 29653176) to Ensembl
Sequene Features : Isoforms 1, Variants 34, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.innate immune response
.negative regulation of type I interferon production
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 34 3
2014-09-19protein level
1 28 3
2014-05-27protein level
1 28 3
2014-02-25protein level
1 28 3
2013-12-09protein level
1 22 3
2013-11-01protein level
1 21 3
2013-09-12protein level
1 21 3
2013-08-17protein level
1 21 3
2013-07-15protein level
1 10 1
2013-06-11protein level
1 10 1
2013-02-12protein level
1 7 1
2012-12-20protein level
1 8 1
2012-10-30protein level
1 8 1
2012-10-07protein level
1 8 1
2012-08-24protein level
1 8 1
2012-07-28protein level
1 8 1
2012-06-08protein level
1 18 1
2012-05-07protein level
1 17 1
2012-04-10protein level
1 17 1
2012-01-13protein level
1 14 1
2011-12-20protein level
1 14 1
2011-11-11protein level
1 14 1
2011-08-23protein level
1 14 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96EQ8-1
13 0 0 26436.8391
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone marrow20
brain7
cervix20
connective tissue26
intestine8
kidney4
liver4
lung14
mammary gland6
placenta10
prostate5
skin37
stomach10
testis6
uterus8
Health State
TissuesTPM*
normal3
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma12
gastrointestinal tumor8
germ cell tumor26
liver tumor10
non-neoplasia41
skin tumor63
Developmental Stage
TissuesTPM*
adult6
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.8
adrenal gland1.5
appendix6.2
bone marrow11.8
cerebral cortex2.3
colon6.2
duodenum10.5
esophagus2.9
gallbladder4.3
heart muscle1.7
kidney1.1
liver5.9
lung5.5
lymph node7.5
ovary1.6
pancreas1.6
placenta3.4
prostate2.3
salivary gland1.4
skin4.3
small intestine12.2
spleen6.7
stomach3.9
testis2.6
thyroid gland1.8
urinary bladder4.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610432, gene) Ring finger protein 125; RNF125OMIM


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