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> Protein (NX_Q96ES7)
Protein (NX_Q96ES7)
Protein
Gene SymbolCCDC101 to neXtProt (NX_Q96ES7)
DescriptionSAGA-associated factor 29 homolog
Chromosome16
Location16p11.2 (28565236 ~ 28603111) to Ensembl
Sequene Features : Isoforms 1, Variants 29, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.establishment of protein localization to chromatin
.histone H3 acetylation
.regulation of transcription, DNA-templated
  + 2 more...
.methylated histone binding .SAGA-type complex
.Ada2/Gcn5/Ada3 transcription activator complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 29 2
2014-09-19protein level
1 23 2
2014-05-27protein level
1 23 2
2014-02-25protein level
1 23 2
2013-12-09protein level
1 20 2
2013-11-01protein level
1 18 1
2013-09-12protein level
1 18 1
2013-08-17protein level
1 18 1
2013-07-15protein level
1 11 1
2013-06-11protein level
1 11 1
2013-02-12protein level
1 6 2
2012-12-20protein level
1 6 2
2012-10-30protein level
1 6 2
2012-10-07protein level
1 6 2
2012-08-24protein level
1 6 2
2012-07-28protein level
1 6 2
2012-06-08protein level
1 21 2
2012-05-07protein level
1 18 2
2012-04-10protein level
1 18 2
2012-01-13protein level
1 14 2
2011-12-20protein level
1 14 2
2011-11-11protein level
1 14 2
2011-08-23protein level
1 14 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96ES7-1
12 0 0 33217.1456
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-743117,EBI-715849 NDC80  
  .attachment of mitotic spindle microtubules to kinetochore
.cell division
.attachment of spindle microtubules to kinetochore
  + 7 more...
.identical protein binding
.structural constituent of cytoskeleton
.Ndc80 complex
.membrane
.cytosol
  + 5 more...
2 EBI-743117,EBI-473249 TADA3  
  .regulation of tubulin deacetylation
.positive regulation of transcription, DNA-templated
.histone H3 acetylation
  + 9 more...
.ligand-dependent nuclear receptor transcription coactivator activity
.protein domain specific binding
.ligand-dependent nuclear receptor binding
  + 2 more...
.mitotic spindle
.transcription factor TFTC complex
.STAGA complex
  + 4 more...
3 EBI-743117,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
4 EBI-743117,EBI-739566 KRT15  
  .activation of mitophagy in response to mitochondrial depolarization
.epidermis development
.scaffold protein binding
.structural constituent of cytoskeleton
.extracellular exosome
.intermediate filament
.nucleus
5 EBI-743117,EBI-79722 HIST1H3A  
  .regulation of gene silencing
.protein heterotetramerization
.negative regulation of gene expression, epigenetic
  + 10 more...
.histone binding
.DNA binding
.extracellular exosome
.protein complex
.membrane
  + 6 more...
6 EBI-743117,EBI-726876 RINT1  
  .regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
.regulation of ER to Golgi vesicle-mediated transport
.Golgi vesicle transport
  + 2 more...
.N/A .endoplasmic reticulum membrane
.endoplasmic reticulum
7 EBI-743117,EBI-10203156 CLHC1  
  .N/A .N/A .N/A
8 EBI-743117,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
9 EBI-743117,EBI-394607 MED4  
  .positive regulation of transcription, DNA-templated
.androgen receptor signaling pathway
.intracellular steroid hormone receptor signaling pathway
  + 3 more...
.thyroid hormone receptor binding
.vitamin D receptor binding
.ligand-dependent nuclear receptor transcription coactivator activity
  + 3 more...
.mediator complex
.membrane
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
blood16
bone13
bone marrow20
brain21
cervix41
connective tissue6
embryonic tissue9
eye62
heart67
intestine38
kidney23
larynx42
liver4
lung17
lymph node11
mammary gland13
muscle56
ovary19
pancreas14
placenta10
prostate10
skin42
spleen74
stomach10
testis27
uterus8
vascular19
Health State
TissuesTPM*
normal23
breast (mammary gland) tumor21
cervical tumor28
chondrosarcoma24
colorectal tumor62
gastrointestinal tumor25
germ cell tumor7
glioma46
head and neck tumor7
kidney tumor14
leukemia10
liver tumor10
lung tumor29
lymphoma55
non-neoplasia20
ovarian tumor26
pancreatic tumor28
primitive neuroectodermal tumor of the CNS15
prostate cancer9
retinoblastoma64
skin tumor71
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult33
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.8
adrenal gland13.7
appendix14.3
bone marrow10.3
cerebral cortex9.2
colon10.8
duodenum12.3
esophagus10.2
gallbladder11
heart muscle10.3
kidney10
liver7.7
lung17.1
lymph node19.1
ovary33.1
pancreas9
placenta8.3
prostate11
salivary gland12.9
skin12.9
small intestine13.4
spleen16.3
stomach11.4
testis31.6
thyroid gland18.3
urinary bladder15.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613374, gene) Coiled-coil domain-containing protein 101; CCDC101OMIM


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