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> Protein (NX_Q96F15)
Protein (NX_Q96F15)
Protein
Gene SymbolGIMAP5 to neXtProt (NX_Q96F15)
DescriptionGTPase IMAP family member 5
Chromosome7
Location7q36.1 (150419341 ~ 150447121) to Ensembl
Sequene Features : Isoforms 2, Variants 72, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of lipid catabolic process
.negative regulation of T cell activation
.regulation of mitochondrial membrane permeability
  + 14 more...
.GTP binding .integral component of membrane
.lysosome
.mitochondrial outer membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 72 3
2014-09-19protein level
2 47 3
2014-05-27protein level
2 47 3
2014-02-25protein level
2 47 3
2013-12-09protein level
2 35 3
2013-11-01protein level
2 33 3
2013-09-12protein level
2 33 3
2013-08-17protein level
2 33 3
2013-07-15protein level
2 26 0
2013-06-11protein level
2 26 0
2013-02-12protein level
2 15 0
2012-12-20protein level
2 14 0
2012-10-30protein level
2 18 0
2012-10-07protein level
2 18 0
2012-08-24transcript level
2 17 0
2012-07-28transcript level
2 17 0
2012-06-08transcript level
2 1 0
2012-05-07transcript level
2 1 0
2012-04-10transcript level
2 1 0
2012-01-13transcript level
2 1 0
2011-12-20transcript level
2 1 0
2011-11-11transcript level
2 1 0
2011-08-23transcript level
2 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96F15-1
1 14 0 34823.7822
NX_Q96F15-2
2 14 0 39559.1831
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6166686,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
2 EBI-6166686,EBI-10173166 LDLRAD1  
  .N/A .N/A .integral component of membrane
3 EBI-6166686,EBI-10264855 LSMEM2  
  .N/A .N/A .integral component of membrane
4 EBI-6166686,EBI-529425 EDA  
  .positive regulation of canonical Wnt signaling pathway
.trachea gland development
.hair follicle placode formation
  + 11 more...
.receptor binding .apical part of cell
.intracellular membrane-bounded organelle
.integral component of membrane
  + 7 more...
5 EBI-6166686,EBI-2832937 GRAMD3  
  .N/A .N/A .cytoplasmic microtubule
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
blood130
bone marrow41
brain23
cervix41
connective tissue33
eye23
heart22
intestine17
kidney33
liver9
lung53
lymph node22
mammary gland6
muscle18
ovary9
placenta10
prostate10
spleen18
stomach10
testis4
thymus12
trachea19
uterus30
Health State
TissuesTPM*
normal7
breast (mammary gland) tumor10
cervical tumor57
chondrosarcoma36
colorectal tumor8
gastrointestinal tumor50
glioma37
head and neck tumor14
kidney tumor29
leukemia52
lung tumor9
non-neoplasia20
Developmental Stage
TissuesTPM*
adult41
fetus32
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue41.1
adrenal gland17.7
appendix69.3
bone marrow5.9
cerebral cortex5.9
colon21
duodenum19.6
esophagus13.3
gallbladder21.6
heart muscle23.3
kidney18.9
liver10.5
lung50.8
lymph node126.1
ovary7.1
pancreas6.4
placenta27.8
prostate10.7
salivary gland9.3
skin7.6
small intestine27.5
spleen80.6
stomach21.6
testis7.6
thyroid gland21
urinary bladder32.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608086, gene) Gtpase, imap family, member 5; GIMAP5OMIM


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