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> Protein (NX_Q96FJ0)
Protein (NX_Q96FJ0)
Protein
Gene SymbolSTAMBPL1 to neXtProt (NX_Q96FJ0)
DescriptionAMSH-like protease
Chromosome10
Location10q23.31 (90639491 ~ 90734910) to Ensembl
Sequene Features : Isoforms 2, Variants 44, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .metal ion binding
.metallopeptidase activity
.membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 44 4
2014-09-19protein level
2 33 4
2014-05-27protein level
2 33 4
2014-02-25protein level
2 33 4
2013-12-09protein level
2 25 4
2013-11-01protein level
2 24 4
2013-09-12protein level
2 24 3
2013-08-17protein level
2 24 3
2013-07-15protein level
2 15 3
2013-06-11protein level
2 15 3
2013-02-12protein level
2 10 4
2012-12-20protein level
2 10 4
2012-10-30protein level
2 10 4
2012-10-07protein level
2 10 2
2012-08-24protein level
2 9 2
2012-07-28protein level
2 9 2
2012-06-08protein level
2 21 2
2012-05-07protein level
2 17 2
2012-04-10protein level
2 17 2
2012-01-13protein level
2 14 2
2011-12-20protein level
2 14 2
2011-11-11protein level
2 14 2
2011-08-23protein level
2 14 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96FJ0-1
0 17 0 49751.2756
NX_Q96FJ0-2
3 17 0 52165.3607
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-745021,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
2 EBI-745021,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
3 EBI-745021,EBI-1045155 MAGEA6  
  .N/A .N/A .N/A
4 EBI-745021,EBI-752037 RAB2A  
  .Rab protein signal transduction
.metabolic process
.Golgi organization
  + 3 more...
.GDP binding
.GTP binding
.GTPase activity
.extracellular exosome
.melanosome
.endoplasmic reticulum-Golgi intermediate compartment membrane
  + 4 more...
5 EBI-745021,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
6 EBI-745021,EBI-6509505 INCA1  
  .positive regulation of apoptotic signaling pathway
.negative regulation of cyclin-dependent protein serine/threonine kinase activity
.negative regulation of cell proliferation
.cyclin binding
.cyclin-dependent protein serine/threonine kinase inhibitor activity
.cytoplasm
.nucleus
7 EBI-745021,EBI-1104907 GNPTAB  
  .carbohydrate phosphorylation
.cell differentiation
.N-glycan processing to lysosome
  + 2 more...
.calcium ion binding
.UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity
.integral component of membrane
.Golgi apparatus
.nucleus
.Golgi membrane
8 EBI-745021,EBI-10232942 LAX1  
  .negative regulation of T cell activation
.antigen receptor-mediated signaling pathway
.immunoglobulin secretion
  + 4 more...
.SH2 domain binding
.protein kinase binding
.integral component of membrane
.membrane
.plasma membrane
  + 2 more...
9 EBI-745021,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
10 EBI-745021,EBI-724829 RNF32  
  .N/A .zinc ion binding .aggresome
.endosome
11 EBI-745021,EBI-739498 CEP72  
  .gamma-tubulin complex localization
.spindle organization
.organelle organization
  + 2 more...
.N/A .cytosol
.centrosome
12 EBI-745021,EBI-747204 IKZF3  
  .regulation of lymphocyte differentiation
.regulation of B cell differentiation
.regulation of apoptotic process
  + 5 more...
.protein heterodimerization activity
.metal ion binding
.sequence-specific DNA binding
  + 2 more...
.plasma membrane
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
blood40
bone41
brain6
cervix61
connective tissue40
embryonic tissue9
esophagus99
eye19
heart44
intestine34
kidney4
liver4
lung23
lymph node22
mammary gland6
muscle28
ovary9
pituitary gland60
placenta7
skin9
spleen168
stomach52
testis48
thymus25
trachea38
uterus4
Health State
TissuesTPM*
normal26
adrenal tumor79
breast (mammary gland) tumor10
cervical tumor57
chondrosarcoma84
colorectal tumor53
esophageal tumor115
gastrointestinal tumor8
germ cell tumor7
kidney tumor14
leukemia52
liver tumor10
lymphoma69
non-neoplasia41
primitive neuroectodermal tumor of the CNS39
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult2
embryoid body14
neonate32
fetus5
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3
adrenal gland22
appendix10.2
bone marrow4
cerebral cortex6.4
colon8.3
duodenum6.6
esophagus4.2
gallbladder4.9
heart muscle5.8
kidney1.5
lung3.3
lymph node16
ovary10.7
placenta1.2
prostate2.1
salivary gland1.2
skin3.6
small intestine7.2
spleen6.6
stomach4.7
testis14.6
thyroid gland1.2
urinary bladder6.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612352, gene) Stam-binding protein-like 1; STAMBPL1OMIM


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