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> Protein (NX_Q96GG9)
Protein (NX_Q96GG9)
Protein
Gene SymbolDCUN1D1 to neXtProt (NX_Q96GG9)
DescriptionDCN1-like protein 1
Chromosome3
Location3q26.33 (182655862 ~ 182703741) to Ensembl
Sequene Features : Isoforms 1, Variants 32, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .nucleus
.ubiquitin ligase complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 32 6
2014-09-19protein level
1 23 6
2014-05-27protein level
1 23 6
2014-02-25protein level
1 23 6
2013-12-09protein level
1 14 6
2013-11-01protein level
1 14 5
2013-09-12protein level
1 14 4
2013-08-17protein level
1 14 4
2013-07-15protein level
1 8 3
2013-06-11protein level
1 8 3
2013-02-12protein level
1 1 3
2012-12-20protein level
1 1 3
2012-10-30protein level
1 1 3
2012-10-07protein level
1 1 3
2012-08-24protein level
1 0 3
2012-07-28protein level
1 0 3
2012-06-08protein level
1 4 3
2012-05-07protein level
1 7 3
2012-04-10protein level
1 7 3
2012-01-13protein level
1 4 3
2011-12-20protein level
1 4 3
2011-11-11protein level
1 4 3
2011-08-23protein level
1 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96GG9-1
9 0 0 30104.967
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-740086,EBI-10175039 TP53BP2  
  .positive regulation of execution phase of apoptosis
.intrinsic apoptotic signaling pathway by p53 class mediator
.negative regulation of cell cycle
  + 7 more...
.NF-kappaB binding
.identical protein binding
.SH3/SH2 adaptor activity
.p53 binding
.perinuclear region of cytoplasm
.cytoplasm
.nucleus
2 EBI-740086,EBI-724310 DAZAP2  
  .N/A .WW domain binding .cytoplasm
.nucleus
3 EBI-740086,EBI-2875665 ARRDC3  
  .negative regulation of locomotion involved in locomotory behavior
.positive regulation of adrenergic receptor signaling pathway
.fat pad development
  + 5 more...
.beta-3 adrenergic receptor binding .plasma membrane
.endosome
4 EBI-740086,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
5 EBI-740086,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
6 EBI-740086,EBI-4400866 VPS37B  
  .positive regulation of viral budding via host ESCRT complex
.positive regulation of viral release from host cell
.intracellular transport of virus
  + 7 more...
.calcium-dependent protein binding .extracellular exosome
.late endosome membrane
.midbody
  + 5 more...
7 EBI-740086,EBI-739510 TRIM39  
  .positive regulation of apoptotic signaling pathway
.negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.protein ubiquitination
.apoptotic process
.identical protein binding
.ligase activity
.zinc ion binding
.cytosol
.mitochondrion
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
ascites25
blood24
bone41
bone marrow20
brain25
cervix20
connective tissue6
embryonic tissue28
eye9
heart33
intestine21
kidney42
lung20
lymph22
lymph node100
mammary gland6
mouth30
muscle37
nerve64
ovary9
pharynx49
placenta14
prostate26
salivary gland49
skin18
testis199
thymus12
uterus38
vascular38
Health State
TissuesTPM*
normal28
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma36
colorectal tumor17
gastrointestinal tumor16
germ cell tumor53
glioma18
kidney tumor29
leukemia42
lung tumor9
lymphoma41
non-neoplasia10
primitive neuroectodermal tumor of the CNS7
prostate cancer28
retinoblastoma43
skin tumor23
soft tissue/muscle tissue tumor39
uterine tumor11
Developmental Stage
TissuesTPM*
adult24
embryoid body14
blastocyst65
fetus34
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.5
adrenal gland12
appendix14.3
bone marrow14.7
cerebral cortex18.4
colon13.8
duodenum11.4
esophagus13.5
gallbladder12.6
heart muscle10.3
kidney13.9
liver16.2
lung8.8
lymph node10.3
ovary10.4
pancreas5.1
placenta11.2
prostate13.2
salivary gland6.2
skin7.9
small intestine12
spleen10.4
stomach11.9
testis140.1
thyroid gland12.4
urinary bladder14.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605905, gene) Dcn1 domain-containing protein 1; DCUN1D1OMIM


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