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> Protein (NX_Q96GP6)
Protein (NX_Q96GP6)
Protein
Gene SymbolSCARF2 to neXtProt (NX_Q96GP6)
DescriptionScavenger receptor class F member 2
Chromosome22
Location22q11.21 (20778874 ~ 20792146) to Ensembl
Sequene Features : Isoforms 2, Variants 54, PTMs 32 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules .scavenger receptor activity .integral component of membrane
.focal adhesion
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 54 32
2014-09-19protein level
2 40 32
2014-05-27protein level
2 40 32
2014-02-25protein level
2 40 32
2013-12-09protein level
2 32 32
2013-11-01protein level
2 31 32
2013-09-12protein level
2 31 31
2013-08-17protein level
2 31 31
2013-07-15protein level
2 26 31
2013-06-11protein level
2 26 31
2013-02-12protein level
2 18 62
2012-12-20protein level
2 19 62
2012-10-30protein level
2 19 62
2012-10-07protein level
2 19 31
2012-08-24protein level
2 15 31
2012-07-28protein level
2 15 31
2012-06-08protein level
2 17 31
2012-05-07protein level
2 17 31
2012-04-10protein level
2 17 31
2012-01-13protein level
1 12 31
2011-12-20protein level
1 12 31
2011-11-11protein level
1 12 31
2011-08-23protein level
1 12 31
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96GP6-1
0 39 0 92417.7604
NX_Q96GP6-2
0 39 0 91755.3539
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1752088,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
bone55
brain13
connective tissue6
embryonic tissue28
eye38
heart33
intestine17
kidney18
lung32
lymph node11
mammary gland19
muscle28
ovary49
pancreas4
prostate5
skin14
stomach20
thymus12
uterus8
Health State
TissuesTPM*
normal17
breast (mammary gland) tumor32
chondrosarcoma156
gastrointestinal tumor8
germ cell tumor15
glioma37
kidney tumor14
leukemia21
lung tumor9
non-neoplasia20
ovarian tumor52
pancreatic tumor9
primitive neuroectodermal tumor of the CNS47
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult13
embryoid body14
blastocyst48
fetus39
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.6
adrenal gland1.7
appendix2.3
cerebral cortex1.3
colon1.9
duodenum1.3
gallbladder6
heart muscle1.4
kidney3.3
lung5.8
lymph node1.3
ovary4.9
placenta4.4
prostate5.2
skin2.1
small intestine1.9
spleen4.5
stomach1.1
testis1.2
thyroid gland1.2
urinary bladder3.4
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexMedium
cervix, uterineHigh
colonMedium
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusMedium
fallopian tubeMedium
gallbladderMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
pancreasHigh
parathyroid glandLow
placentaHigh
prostateHigh
rectumHigh
salivary glandMedium
seminal vesicleLow
skeletal muscleLow
skin 1High
skin 2High
small intestineHigh
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#600920, phenotype) Van den ende-gupta syndrome; VDEGSOMIM
2(*613619, gene) Scavenger receptor class f, member 2; SCARF2OMIM


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