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> Protein (NX_Q96GY3)
Protein (NX_Q96GY3)
Protein
Gene SymbolLIN37 to neXtProt (NX_Q96GY3)
DescriptionProtein lin-37 homolog
Chromosome19
Location19q13.12 (36239262 ~ 36245420) to Ensembl
Sequene Features : Isoforms 1, Variants 23, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of cell cycle
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .transcriptional repressor complex
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 23 6
2014-09-19protein level
1 17 6
2014-05-27protein level
1 17 6
2014-02-25protein level
1 9 6
2013-12-09protein level
1 2 6
2013-11-01protein level
1 2 5
2013-09-12protein level
1 2 4
2013-08-17protein level
1 2 4
2013-07-15protein level
1 2 4
2013-06-11protein level
1 2 4
2013-02-12protein level
1 2 6
2012-12-20protein level
1 4 6
2012-10-30protein level
1 5 6
2012-10-07protein level
1 5 6
2012-08-24protein level
1 5 6
2012-07-28protein level
1 5 6
2012-06-08protein level
1 5 6
2012-05-07protein level
1 4 6
2012-04-10protein level
1 4 6
2012-01-13protein level
1 2 6
2011-12-20protein level
1 4 6
2011-11-11protein level
1 4 6
2011-08-23protein level
1 4 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96GY3-1
8 0 0 28365.0499
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-748884,EBI-1045155 MAGEA6  
  .N/A .N/A .N/A
2 EBI-748884,EBI-1181367 CDR2  
  .N/A .N/A .cytoplasm
3 EBI-748884,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
4 EBI-748884,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
5 EBI-748884,EBI-742397 TEX11  
  .chiasma assembly
.negative regulation of apoptotic process
.fertilization
  + 6 more...
.N/A .central element
6 EBI-748884,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
7 EBI-748884,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
8 EBI-748884,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
9 EBI-748884,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
10 EBI-748884,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
11 EBI-748884,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bone41
brain10
cervix20
connective tissue6
embryonic tissue23
eye38
heart89
intestine12
kidney14
lung32
lymph node11
mammary gland6
mouth15
nerve64
ovary29
pancreas18
placenta45
prostate21
skin14
spleen37
stomach10
testis20
tonsil58
uterus12
Health State
TissuesTPM*
normal25
breast (mammary gland) tumor10
chondrosarcoma24
colorectal tumor8
germ cell tumor15
glioma18
head and neck tumor7
leukemia21
non-neoplasia10
ovarian tumor26
pancreatic tumor9
primitive neuroectodermal tumor of the CNS7
retinoblastoma43
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult24
embryoid body28
fetus30
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.7
adrenal gland7.7
appendix8.1
bone marrow5.2
cerebral cortex7.2
colon5.7
duodenum8.3
esophagus9
gallbladder9
heart muscle9.9
kidney6.9
liver4.2
lung10.4
lymph node12
ovary12.5
pancreas4.5
placenta12.2
prostate8.3
salivary gland5.7
skin11.2
small intestine6.7
spleen8.5
stomach7.4
testis10.1
thyroid gland8.8
urinary bladder8.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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