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> Protein (NX_Q96HA1)
Protein (NX_Q96HA1)
Protein
Gene SymbolPOM121 to neXtProt (NX_Q96HA1)
DescriptionNuclear envelope pore membrane protein POM 121
Chromosome7
Location7q11.23 (72349936 ~ 72421979) to Ensembl
Sequene Features : Isoforms 3, Variants 130, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of cellular response to heat
.transmembrane transport
.mRNA transport
  + 17 more...
.N/A .nuclear membrane
.endoplasmic reticulum membrane
.nuclear pore
.nuclear envelope
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 130 7
2014-09-19protein level
3 93 7
2014-05-27protein level
3 93 22
2014-02-25protein level
3 93 20
2013-12-09protein level
3 86 20
2013-11-01protein level
3 85 19
2013-09-12protein level
3 85 19
2013-08-17protein level
3 85 19
2013-07-15protein level
3 55 16
2013-06-11protein level
3 55 16
2013-02-12protein level
3 37 44
2012-12-20protein level
3 35 44
2012-10-30protein level
3 34 44
2012-10-07protein level
3 34 16
2012-08-24protein level
3 32 16
2012-07-28protein level
3 32 16
2012-06-08protein level
3 6 16
2012-05-07protein level
3 6 16
2012-04-10protein level
3 6 16
2012-01-13protein level
3 6 16
2011-12-20protein level
3 6 16
2011-11-11protein level
3 6 16
2011-08-23protein level
3 6 16
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96HA1-1
9 9 18 127641.7373
NX_Q96HA1-2
0 9 15 98976.3197
NX_Q96HA1-3
2 8 15 100802.2368
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-739990,EBI-712648 AGR2  
  .mucus secretion
.lung goblet cell differentiation
.dystroglycan binding .endoplasmic reticulum
.mitochondrion
.extracellular region
2 EBI-739990,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
3 EBI-739990,EBI-10236271 PAXIP1  
  .chorion development
.adipose tissue development
.positive regulation of transcription initiation from RNA polymerase II promoter
  + 13 more...
.N/A .histone methyltransferase complex
.nuclear matrix
.nucleus
4 EBI-739990,EBI-742397 TEX11  
  .chiasma assembly
.negative regulation of apoptotic process
.fertilization
  + 6 more...
.N/A .central element
5 EBI-739990,EBI-742887 CEP76  
  .regulation of centriole replication
.organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .protein complex
.cytosol
.centriole
.centrosome
6 EBI-739990,EBI-740322 RBPMS  
  .positive regulation of SMAD protein import into nucleus
.positive regulation of pathway-restricted SMAD protein phosphorylation
.RNA processing
  + 2 more...
.poly(A) RNA binding
.poly(A) binding
.transcription coactivator activity
.nucleotide binding
.cytoplasm
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland121
ascites251
bladder33
blood8
bone13
bone marrow20
brain2
cervix20
connective tissue33
embryonic tissue14
esophagus49
eye9
heart89
intestine21
kidney14
larynx85
liver53
lung2
lymph45
lymph node55
mammary gland85
mouth211
muscle56
ovary19
pancreas4
parathyroid48
pharynx73
placenta10
prostate147
skin223
spleen18
stomach41
testis2
thymus125
thyroid64
trachea19
uterus4
vascular38
Health State
TissuesTPM*
normal6
adrenal tumor316
breast (mammary gland) tumor85
cervical tumor144
chondrosarcoma12
colorectal tumor44
esophageal tumor57
gastrointestinal tumor126
germ cell tumor3
glioma111
head and neck tumor127
kidney tumor14
leukemia21
liver tumor52
lung tumor77
lymphoma41
non-neoplasia41
ovarian tumor26
pancreatic tumor9
primitive neuroectodermal tumor of the CNS118
prostate cancer192
retinoblastoma150
skin tumor295
soft tissue/muscle tissue tumor103
uterine tumor11
Developmental Stage
TissuesTPM*
adult8
embryoid body14
blastocyst32
fetus3
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue17.2
adrenal gland13.5
appendix17.3
bone marrow23.5
cerebral cortex15.1
colon12.8
duodenum17.9
esophagus12.9
gallbladder14
heart muscle9.3
kidney12
liver9.1
lung15
lymph node21.4
ovary16.2
pancreas11.9
placenta15.9
prostate14.3
salivary gland12.6
skin16.4
small intestine16.6
spleen19.8
stomach14.2
testis18
thyroid gland15.8
urinary bladder14
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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