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> Protein (NX_Q96HB5)
Protein (NX_Q96HB5)
Protein
Gene SymbolCCDC120 to neXtProt (NX_Q96HB5)
DescriptionCoiled-coil domain-containing protein 120
ChromosomeX
LocationXp11.23 (48911101 ~ 48927509) to Ensembl
Sequene Features : Isoforms 4, Variants 58, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 58 7
2014-09-19protein level
4 45 7
2014-05-27protein level
4 44 7
2014-02-25protein level
3 45 7
2013-12-09protein level
3 37 7
2013-11-01protein level
3 36 7
2013-09-12protein level
3 36 7
2013-08-17protein level
3 36 7
2013-07-15protein level
2 22 7
2013-06-11protein level
2 22 7
2013-02-12protein level
2 13 6
2012-12-20protein level
2 12 6
2012-10-30protein level
2 14 6
2012-10-07protein level
2 14 3
2012-08-24protein level
2 12 3
2012-07-28protein level
2 12 3
2012-06-08protein level
2 7 3
2012-05-07protein level
2 7 3
2012-04-10protein level
2 7 3
2012-01-13protein level
1 1 3
2011-12-20protein level
1 1 3
2011-11-11protein level
1 1 3
2011-08-23protein level
1 1 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96HB5-1
0 31 0 67525.599
NX_Q96HB5-2
1 30 0 66312.9885
NX_Q96HB5-3
0 33 0 70867.2589
NX_Q96HB5-4
2 33 0 74923.2566
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10185348,EBI-741648 CYTH3  
  .establishment of epithelial cell polarity
.Golgi vesicle transport
.positive regulation of cell adhesion
  + 2 more...
.phosphatidylinositol-3,4,5-trisphosphate binding
.ARF guanyl-nucleotide exchange factor activity
.extrinsic component of cytoplasmic side of plasma membrane
.plasma membrane
.cytosol
.ruffle
2 EBI-10185348,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
3 EBI-10185348,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
4 EBI-10185348,EBI-2808286 CCDC57  
  .N/A .N/A .N/A
5 EBI-10185348,EBI-2349927 EFHC2  
  .N/A .calcium ion binding .N/A
6 EBI-10185348,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
7 EBI-10185348,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
8 EBI-10185348,EBI-743488 CEP170P1  
  .N/A .identical protein binding .N/A
9 EBI-10185348,EBI-448974 CYTH2  
  .positive regulation of GTPase activity
.regulation of cell adhesion
.actin cytoskeleton organization
.endocytosis
.inositol 1,4,5 trisphosphate binding
.lipid binding
.ARF guanyl-nucleotide exchange factor activity
.membrane
.plasma membrane
.cytoplasm
10 EBI-10185348,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder66
bone27
bone marrow20
brain25
embryonic tissue18
intestine34
kidney4
lung14
mammary gland19
mouth120
ovary9
pancreas9
pharynx49
placenta42
prostate15
stomach10
testis2
trachea96
uterus12
Health State
TissuesTPM*
normal16
adrenal tumor79
bladder carcinoma113
breast (mammary gland) tumor21
colorectal tumor35
gastrointestinal tumor8
germ cell tumor7
head and neck tumor67
ovarian tumor13
pancreatic tumor19
prostate cancer19
uterine tumor11
Developmental Stage
TissuesTPM*
adult15
embryoid body14
blastocyst16
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.4
adrenal gland1.9
appendix2
bone marrow1.4
cerebral cortex2.2
colon3.4
duodenum9.5
esophagus10.9
gallbladder3.7
kidney3.5
liver1.7
lung4.3
lymph node2.3
ovary4.3
pancreas2.8
placenta5.6
prostate5.1
salivary gland5.4
skin16.9
small intestine7.8
spleen3.1
stomach7.2
testis3
thyroid gland3.4
urinary bladder3.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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