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> Protein (NX_Q96HR3)
Protein (NX_Q96HR3)
Protein
Gene SymbolMED30 to neXtProt (NX_Q96HR3)
DescriptionMediator of RNA polymerase II transcription subunit 30
Chromosome8
Location8q24.11 (118532952 ~ 118552501) to Ensembl
Sequene Features : Isoforms 2, Variants 23, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of transcription, DNA-templated
.androgen receptor signaling pathway
.intracellular steroid hormone receptor signaling pathway
  + 4 more...
.thyroid hormone receptor binding
.vitamin D receptor binding
.ligand-dependent nuclear receptor transcription coactivator activity
  + 3 more...
.mediator complex
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 23 2
2014-09-19protein level
2 20 2
2014-05-27protein level
2 20 2
2014-02-25protein level
1 20 2
2013-12-09protein level
1 15 2
2013-11-01protein level
1 15 1
2013-09-12protein level
1 15 1
2013-08-17protein level
1 15 1
2013-07-15protein level
1 10 1
2013-06-11protein level
1 10 1
2013-02-12protein level
1 7 2
2012-12-20protein level
1 7 2
2012-10-30protein level
1 7 2
2012-10-07protein level
1 7 2
2012-08-24protein level
1 5 2
2012-07-28protein level
1 5 2
2012-06-08protein level
1 5 2
2012-05-07protein level
1 5 2
2012-04-10protein level
1 5 2
2012-01-13protein level
1 3 2
2011-12-20protein level
1 3 2
2011-11-11protein level
1 3 2
2011-08-23protein level
1 3 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96HR3-1
1 6 0 20264.2291
NX_Q96HR3-2
1 6 0 16268.268
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-394659,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
2 EBI-394659,EBI-10174653 DOCK8  
  .negative regulation of T cell apoptotic process
.memory T cell proliferation
.dendritic cell migration
  + 3 more...
.guanyl-nucleotide exchange factor activity .cell leading edge
.membrane
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bone27
brain14
connective tissue13
eye23
heart11
lung11
lymph45
lymph node77
mammary gland19
ovary49
pancreas9
placenta17
prostate15
testis25
uterus12
Health State
TissuesTPM*
normal15
breast (mammary gland) tumor10
chondrosarcoma12
germ cell tumor22
glioma18
lymphoma27
ovarian tumor65
retinoblastoma86
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult14
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.2
adrenal gland9.5
appendix11.7
bone marrow29
cerebral cortex5.5
colon13.6
duodenum8.5
esophagus9.9
gallbladder7.6
heart muscle6.3
kidney7.4
liver8.9
lung11.6
lymph node17.7
ovary14.4
pancreas3.2
placenta9.3
prostate10.8
salivary gland5.9
skin7.7
small intestine10
spleen12.7
stomach7.6
testis10.2
thyroid gland8.5
urinary bladder8.9
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*610237, gene) Mediator complex subunit 30; MED30OMIM


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