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> Protein (NX_Q96II8)
Protein (NX_Q96II8)
Protein
Gene SymbolLRCH3 to neXtProt (NX_Q96II8)
DescriptionLeucine-rich repeat and calponin homology domain-containing protein 3
Chromosome3
Location3q29 (197518097 ~ 197615307) to Ensembl
Sequene Features : Isoforms 4, Variants 94, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .cytoplasm
.extracellular region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 94 4
2014-09-19protein level
3 78 4
2014-05-27protein level
3 78 4
2014-02-25protein level
3 77 4
2013-12-09protein level
3 52 4
2013-11-01protein level
3 50 4
2013-09-12protein level
3 50 4
2013-08-17protein level
3 50 4
2013-07-15protein level
3 31 4
2013-06-11protein level
3 31 4
2013-02-12protein level
3 13 9
2012-12-20protein level
3 14 9
2012-10-30protein level
3 23 9
2012-10-07protein level
3 23 3
2012-08-24protein level
3 23 3
2012-07-28protein level
3 23 3
2012-06-08protein level
3 25 3
2012-05-07protein level
3 19 3
2012-04-10protein level
3 19 3
2012-01-13protein level
3 8 3
2011-12-20protein level
3 8 3
2011-11-11protein level
3 8 3
2011-08-23protein level
3 8 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96II8-1
0 33 2 86029.7151
NX_Q96II8-2
2 30 2 89060.0792
NX_Q96II8-3
1 29 1 78752.8025
NX_Q96II8-4
2 28 2 80396.9005
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-8795942,EBI-10174653 DOCK8  
  .negative regulation of T cell apoptotic process
.memory T cell proliferation
.dendritic cell migration
  + 3 more...
.guanyl-nucleotide exchange factor activity .cell leading edge
.membrane
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
blood40
bone marrow41
brain5
connective tissue33
embryonic tissue9
esophagus49
eye4
heart33
intestine17
kidney47
larynx170
liver4
lung29
lymph node189
mammary gland39
mouth105
muscle84
ovary39
pancreas23
placenta38
skin23
spleen37
stomach20
testis75
thymus50
thyroid21
trachea57
uterus43
vascular38
Health State
TissuesTPM*
normal8
breast (mammary gland) tumor32
chondrosarcoma24
colorectal tumor26
esophageal tumor57
gastrointestinal tumor8
germ cell tumor30
glioma46
head and neck tumor89
kidney tumor14
leukemia52
liver tumor10
lung tumor9
non-neoplasia10
ovarian tumor39
pancreatic tumor9
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor79
Developmental Stage
TissuesTPM*
adult4
embryoid body28
neonate32
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.9
adrenal gland12
appendix14.9
bone marrow5.8
cerebral cortex12.5
colon12.5
duodenum8.3
esophagus12.6
gallbladder13.2
heart muscle12.6
kidney8.7
liver7.6
lung12.4
lymph node21
ovary20.2
pancreas5.2
placenta10.9
prostate17.3
salivary gland9
skin11
small intestine9.3
spleen14.6
stomach12.1
testis16.6
thyroid gland10.9
urinary bladder14.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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