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> Protein (NX_Q96IZ5)
Protein (NX_Q96IZ5)
Protein
Gene SymbolRBM41 to neXtProt (NX_Q96IZ5)
DescriptionRNA-binding protein 41
ChromosomeX
LocationXq22.3 (106307650 ~ 106362057) to Ensembl
Sequene Features : Isoforms 3, Variants 48, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .RNA binding
.nucleotide binding
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 48 1
2014-09-19protein level
3 40 1
2014-05-27protein level
3 40 1
2014-02-25protein level
3 39 1
2013-12-09protein level
3 30 1
2013-11-01protein level
3 29 1
2013-09-12protein level
3 29 1
2013-08-17protein level
3 29 1
2013-07-15protein level
3 23 1
2013-06-11protein level
3 23 1
2013-02-12protein level
3 14 2
2012-12-20protein level
3 12 2
2012-10-30protein level
3 15 2
2012-10-07protein level
3 15 1
2012-08-24protein level
3 11 1
2012-07-28protein level
3 11 1
2012-06-08protein level
3 12 1
2012-05-07protein level
3 12 1
2012-04-10protein level
3 12 1
2012-01-13protein level
3 5 1
2011-12-20protein level
3 5 1
2011-11-11protein level
3 5 1
2011-08-23protein level
3 5 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96IZ5-1
1 19 0 47069.9754
NX_Q96IZ5-2
1 19 0 46307.6379
NX_Q96IZ5-3
3 10 0 35939.3888
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-740773,EBI-357966 HNRNPC  
  .3'-UTR-mediated mRNA stabilization
.ATP-dependent chromatin remodeling
.gene expression
  + 3 more...
.N6-methyladenosine-containing RNA binding
.poly(A) RNA binding
.identical protein binding
  + 7 more...
.catalytic step 2 spliceosome
.extracellular exosome
.protein complex
  + 6 more...
2 EBI-740773,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
3 EBI-740773,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
4 EBI-740773,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
5 EBI-740773,EBI-2340269 MKRN3  
  .protein ubiquitination .ligase activity
.zinc ion binding
.ribonucleoprotein complex
6 EBI-740773,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
7 EBI-740773,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
8 EBI-740773,EBI-726876 RINT1  
  .regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
.regulation of ER to Golgi vesicle-mediated transport
.Golgi vesicle transport
  + 2 more...
.N/A .endoplasmic reticulum membrane
.endoplasmic reticulum
9 EBI-740773,EBI-741520 RALYL  
  .N/A .poly(A) RNA binding
.identical protein binding
.nucleotide binding
.N/A
10 EBI-740773,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
11 EBI-740773,EBI-2548751 MIPOL1  
  .N/A .N/A .nucleus
12 EBI-740773,EBI-413317 SPAG5  
  .regulation of attachment of spindle microtubules to kinetochore
.cell division
.chromosome segregation
  + 2 more...
.N/A .mitotic spindle
.microtubule plus-end
.midbody
  + 7 more...
13 EBI-740773,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
14 EBI-740773,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
15 EBI-740773,EBI-719716 NINL  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.calcium ion binding .microtubule
.cytosol
.microtubule organizing center
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder234
bone13
bone marrow20
brain9
cervix20
embryonic tissue37
esophagus49
eye19
intestine30
kidney18
liver19
lung11
lymph node44
mammary gland26
mouth45
muscle18
ovary9
pancreas4
pituitary gland60
placenta31
prostate21
skin14
stomach20
testis6
thymus12
thyroid64
trachea38
uterus43
vascular19
Health State
TissuesTPM*
normal19
bladder carcinoma284
breast (mammary gland) tumor21
cervical tumor28
chondrosarcoma12
colorectal tumor62
esophageal tumor57
gastrointestinal tumor16
germ cell tumor26
glioma9
head and neck tumor37
kidney tumor29
leukemia10
non-neoplasia10
ovarian tumor13
prostate cancer19
skin tumor7
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult23
embryoid body85
blastocyst16
fetus17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.3
adrenal gland8
appendix7.3
bone marrow3.5
cerebral cortex5.5
colon7.9
duodenum10
esophagus7.4
gallbladder7.4
heart muscle6.3
kidney8
liver5.8
lung6.7
lymph node7
ovary7.9
pancreas1.9
placenta6.5
prostate7
salivary gland4.8
skin7.5
small intestine8.8
spleen6.3
stomach6.6
testis8.3
thyroid gland9.1
urinary bladder8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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